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Daniela Vecchio

As seen in: Nature, MDPI, JAMA Psychiatry, Thy Magazine
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Articles by Daniela Vecchio

Brain Morphology Mediators of the Association of Childhood Trauma With Bipolar Disorder : An International ENIGMA Bipolar Disorder Working Group Study

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By Leonardo Tozzi, Maria R. Dauvermann, Emma Corley, Andréa Fernandes, Melody J. Y. Kang, Yanghee Im, Leila Nabulsi, Roberto Goya-Maldonado, Klaus Berger, Marco Hermesdorf, Hilary P. Blumberg, Lejla Colic, Tamsyn Van Rheenen, Elysha Ringin, Susan L Rossell, James A. Karantonis, Lisa Furlong, Tilo Kircher, Frederike Stein, Udo Dannlowski, Dominik Grotegerd, Jair C. Soares, Mon-Ju Wu, Giovana Zunta-Soares, Benson Mwangi, Joaquim Radua, Enric Vilajosana, Eduard Vieta, Melissa Green, Emilie Olié, Guillaume Clain, Francesco Benedetti, Elisa MT Melloni, Beatrice Bravi, Delfina Janiri, Daniela Vecchio, Fabrizio Piras, Nerisa Banaj, Gabriele Sani, Gloria Roberts, Janice M. Fullerton, Bronwyn Overs, Philip Mitchell, Jonathan Savitz, Lakshmi N Yatham, Josselin Houenou, Marion Leboyer, Amanda L. Rodrigue, Amanda Bautista Rodrígue, David Glahn, Sophia I. Thomopoulos, Neda Jahanshad, Paul Thompson, Ole A. Andreassen, Christopher R. K. Ching, Dara M. Cannon, Yann Quidé
| JAMA Psychiatry Verified
Brain Morphology Mediators of the Association of Childhood Trauma With Bipolar Disorder: An International ENIGMA Bipolar Disorder Working Group Study Key Points Question Is the association of childhood trauma and bipolar disorder mediated by brain structure?
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Cerebral cortical alterations in adolescent early-onset psychosis: a surface-based morphometry mega-analysis

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By Stener Nerland, Claudia Barth, Kjetil Nordbø Jørgensen, Laura A. Wortinger, Josefina Castro-Fornieles, Covadonga M Díaz-Caneja, Joost Janssen, Celso Arango, Gisela Sugranyes, Inmaculada Baeza, Fabrizio Piras, Nerisa Banaj, Federica Piras, Simone Elia, Daniela Vecchio, Mathias Lundberg, Bjørn Rishovd Rund, Adriana Fortea, Christian K. Tamnes, Lars T. Westlye, Dimitrios Andreou, Erik Jönsson, Matthew J Kempton, Shuqing Si, Marinos Kyriakopoulos, Carrie E. Bearden, Saül Pascual-Diaz, Anne-Kathrin J. Fett, Katherine H. Karlsgodt, Lydia Krabbendam, Peter Kochunov, Sophia I. Thomopoulos, Neda Jahanshad, Anthony James, Sophia Frangou, Nils Eiel Steen, Ole A. Andreassen, Paul Thompson Verified, Ingrid Agartz, Hannes Bohman, Elena de la Serna, Runar E. Smelror, Kristen Laulette, Anne M. Myhre
| Nature Verified
Abstract Cortical brain morphology in early-onset psychosis (EOP; age of onset <19 years) is poorly understood, partly due to recruitment constraints linked to its low incidence. We pooled T1-weighted magnetic resonance imaging (MRI) data from 387 adolescents with EOP (mean age=16.1 ± 1.5; 49.6% female) and 338 healthy controls (CTR; mean age=15.8 ± 1.9, 54.4% female) from nine research sites worldwide.
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Structural brain abnormalities and aggression in schizophrenia: mega-analysis of data from 2095 patients and 2861 healthy controls via the ENIGMA consortium | Molecular Psychiatry

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By Seyed M. Kia, Wiepke Cahn, Nerisa Banaj, Katharina Brosch, Rachel M. Brouwer, Vince Calhoun, Sunah Choi, Young-Chul Chung, Derin Cobia, Sirio Cocozza, Andrea de Bartolomeis, Marta Di Forti, Alexandre Dumais, Ulrika Evermann, Kira Flinkenflügel, Foivos Georgiadis, David Glahn, Janik Goltermann, Melissa Green, Dominik Grotegerd, Hilleke Hulshoff Pol, Felice Iasevoli, Andriana Karuk, Minah Kim, Tilo Kircher, Matthias Kirschner, Jun Soo Kwon, Rebekka Lencer, Tiago R Marques, Susanne Meinert, Robin Murray, Igor Nenadic, Godfrey Pearlson, Fabrizio Piras, Giuseppe Pontillo, Yann Quidé, Amanda L. Rodrigue, Amanda Bautista Rodrígue, Kang Hee Sim, Antonin Skoch, Gianfranco Spalletta, Filip Spaniel, Florian Thomas-Odenthal, David Tomecek, Mario Tranfa, Jessica Turner, Daniela Vecchio, Adrian Wroblewski, Arturo Brunetti
| Nature Verified
Abstract It is hypothesised that structural brain abnormalities in individuals with schizophrenia are associated with aggressive behaviour, but this has not been tested directly. We pooled magnetic resonance imaging and clinical data from 2095 patients and 2861 healthy control subjects across 20 sites of the ENIGMA-Schizophrenia Working Group.
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Contribution of Cerebellar Glutamatergic and GABAergic Systems in Premotor and Early Stages of Parkinson’s Disease

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By Clelia Pellicano, Daniela Vecchio, Federico Giove, Lucia Macchiusi
| Preprints.org
Submitted: 15 October 2025 You are already at the latest version Parkinson’s disease (PD) is a multisystem disorder, with early changes extending beyond basal ganglia circuitries and involving non-dopaminergic pathways, including cerebellar networks. Whether cerebellar dysfunction reflects a compensatory mechanism or an intrinsic hallmark of disease progression remains unresolved.
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A' Design Awards & Competition 2026 – Call for Submissions — Thy Magazine

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By Daniela Vecchio
| Thy Magazine Verified
L’A’ Design Award & Competition è tra i riconoscimenti internazionali più autorevoli dedicati al mondo del design. Nato per valorizzare la creatività e l’innovazione, il premio riunisce ogni anno designer, architetti, artisti e brand provenienti da ogni parte del globo, con la missione di promuovere progetti capaci di migliorare la società.
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Illustrazioni fresche, colorate e ironiche in una parola: Istriceillustra — Thy Magazine

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By Daniela Vecchio
| Thy Magazine Verified
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Mapping gray and white matter volume abnormalities in early-onset psychosis: an ENIGMA multicenter voxel-based morphometry study - Molecular Psychiatry

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By Shuqing Si, Cheryl See, Sonia Ambrogi, Celso Arango, Nerisa Banaj, Josefina Castro-Fornieles, Jacob J. Crouse, Covadonga M Díaz-Caneja, Anne-Kathrin J. Fett, Adriana Fortea, Ian B Hickie, Joost Janssen, Kody G. Kennedy, Bradley J. MacIntosh, Pedro Morgado, Stener Nerland, Saül Pascual-Diaz, Maria Picó-Pérez, Fabrizio Piras, Gisela Sugranyes, Chao Suo, Daniela Vecchio, Philip K. McGuire, Claudia Barth, Anthony James
| Nature Verified
Abstract Regional gray matter (GM) alterations have been reported in early-onset psychosis (EOP, onset before age 18), but previous studies have yielded conflicting results, likely due to small sample sizes and the different brain regions examined. In this study, we conducted a whole brain voxel-based morphometry (VBM) analysis in a large sample of individuals with EOP, using the newly developed ENIGMA-VBM tool. 15 independent cohorts from the ENIGMA-EOP working group participated in the study.
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Game Transfer Phenomena in a Clinical Case with Psychosis and Gaming Disorder

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By Daniela Vecchio, Huu Kim Le, Annabel Callan, Daragh Poynton
| MDPI
1. Introduction This case report describes a 24-year-old male diagnosed with paranoid schizophrenia with a history of intensive video game playing, diagnosed with Gaming Disorder (GD).
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Cortical morphology in patients with the deficit and non-deficit syndrome of schizophrenia: a worldwide meta- and mega-analyses - Molecular Psychiatry

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By Nerisa Banaj, Daniela Vecchio, Fabrizio Piras, Juan R. Bustillo, Erin W. Dickie, Judith M. Ford, Bernd Kraemer, Stephen M Lawrie, Daniel H. Mathalon, Robin Murray, Akira Sawa, Freda Scheffler, Kang Hee Sim, Filip Spaniel, Dan Stein, David Tomecek, Aristotle N. Voineskos, Neda Jahanshad
| Nature Verified
Abstract Converging evidence suggests that schizophrenia (SZ) with primary, enduring negative symptoms (i.e., Deficit SZ (DSZ)) represents a distinct entity within the SZ spectrum while the neurobiological underpinnings remain undetermined.
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Partecipa all'A' Design Awards – Call for Entries — Thy Magazine

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By Daniela Vecchio
| Thy Magazine Verified
Tra i milioni di prodotti e design che ogni anno vengono lanciati nel mondo, spiccano quelli vincitori dell’A’ Design Award. Il premio, infatti, nasce dal desiderio di sottolineare i migliori design e i prodotti ben progettati. Cos’è l’A’ Design Award? Si tratta di uno dei più prestigiosi concorsi internazionali incentrati sul design in tutte le sue forme.
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Brain Network Topology in Deficit and Non-Deficit Schizophrenia: Application of Graph Theory to Local and Global Indices

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By Daniela Vecchio, Fabrizio Piras, Valentina Ciullo, Federica Piras
| MDPI
Altmetric share Share announcement Help format_quote Cite thumb_up ... Endorse textsms ... Comment Need Help? Support Find support for a specific problem in the support section of our website. Get Support Feedback Please let us know what you think of our products and services. Give Feedback Information Visit our dedicated information section to learn more about MDPI.
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In vivo white matter microstructure in adolescents with early-onset psychosis: a multi-site mega-analysis - Molecular Psychiatry

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By Claudia Barth, Sonia Ambrogi, Ole A. Andreassen, Celso Arango, Carrie E. Bearden, Covadonga M Díaz-Caneja, Tiril P. Gurholt, Anthony James, Fabrizio Piras, Gianfranco Spalletta, Gisela Sugranyes, Chao Suo, Diana Tordesillas-Gutiérrez, Daniela Vecchio, Josefina Castro-Fornieles, Joost Janssen, Laura A. Wortinger
| Nature Verified
Study sample The ENIGMA-EOP Working Group obtained case-control data from nine cohorts across seven countries (for information on each cohort, please see Supplementary Table S1, S2, and S3), yielding imaging and clinical data on a combined total of 321 adolescents with early-onset psychosis (EOP) and 265 age-matched healthy controls. Participants were aged 12 to 18 years at MRI image acquisition.
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Brain ageing in schizophrenia: evidence from 26 international cohorts via the ENIGMA Schizophrenia consortium - Molecular Psychiatry

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By Clara Alloza, Celso Arango, Rosa Ayesa-Arriola, Juan R. Bustillo, Oleg Bykhovski, Vince Calhoun, Vaughan J. Carr, Covadonga M Díaz-Caneja, Gary Donohoe, Stefan K. Ehrlich, Paola Fuentes-Claramonte, Melissa Green, Tim Hahn Verified, Frans Henskens, Philipp Homan, Ellen Ji, Minah Kim, Matthias Kirschner, Jun Soo Kwon, Jingyu Liu, Patricia Mitchie, Stijn Michielse, Bryan J. Mowry, Christos Pantelis, Giulio Pergola, Fabrizio Piras, Yann Quidé, Salvador Sarró, André Schmidt, Rodney Scott, Antonin Skoch, Gianfranco Spalletta, Filip Spaniel, David Tomecek, Javier Vázquez-Bourgon, Daniela Vecchio, Aristotle N. Voineskos, Thomas Weickert, Lianne Schmaal, Jessica Turner
| Nature Verified
Study samples Twenty-six cohorts from the ENIGMA SZ working group with cross-sectional data from SZ patients (N = 2803) and healthy controls (N = 2598) were included in this study (18–73 years of age). Details of demographics, location, clinical characteristics (including methods for data harmonization), and inclusion/exclusion criteria for each cohort may be found in Supplementary Information (Supplementary Tables S1–3, Supplementary Fig. S1, and Supplementary Material).
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