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David Barras on Muck Rack

David Barras

Indianapolis
As seen in: Nature, Science Magazine, BioRxiv, Cell Press, WISH-TV (Indianapolis, IN), Cancer Discovery, WTHI-TV (Terre Haute, IN), Northumberland Gazette
Retired Anchor/Reporter WISHTV. Grandpa
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Articles

Cancer cells impair monocyte-mediated T cell stimulation to evade immunity - Nature

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By Anais Elewaut, Felix Bayerl, Martin Schönlein, Trung Nguyen, Trung Nguyễn, Francesco Andreatta, Milica Vulin, Felix Holstein, Denarda Dangaj Laniti, David Barras, George Coukos, Camelia Quek, Johannes Zuber, Göran Jonsson, Jan P. Böttcher, Sakari Vanharanta, Guillem Estivill, Jonas Bayerl
| Nature Verified
Abstract The tumour microenvironment is programmed by cancer cells and substantially influences anti-tumour immune responses1,2. Within the tumour microenvironment, CD8+ T cells undergo full effector differentiation and acquire cytotoxic anti-tumour functions in specialized niches3,4,5,6,7. Although interactions with type 1 conventional dendritic cells have been implicated in this process3,4,5,8,9,10, the underlying cellular players and molecular mechanisms remain incompletely understood.
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Tumor-reactive T cell clonotype dynamics underlying clinical response to TIL therapy in melanoma

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By Johanna Chiffelle, Lausanne Branch, David Barras, Angela Orcurto
| Cell Press Verified
Keywords melanoma tumor-infiltrating lymphocytes adoptive cell transfer cancer immunotherapy tumor reactivity expansion tumor engraftment exhaustion cell state clonotype dynamics Get full text access Log in, subscribe or purchase for full access. References 1. Dafni, U. ∙ Michielin, O. ∙ Lluesma, S.M. ... Efficacy of adoptive therapy with tumor-infiltrating lymphocytes and recombinant interleukin-2 in advanced cutaneous melanoma: a systematic review and meta-analysis Ann. Oncol. 2019; 30:1902-1913 2.
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Author Correction: Identification of clinically relevant T cell receptors for personalized T cell therapy using combinatorial algorithms - Nature Biotechnology

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By Remy Petremand, Johanna Chiffelle, Marion Arnaud, David Barras, Maria Lozano-Rabella, Raphael Genolet, Jonathan Moore, Lana E. Kandalaft, Michal Bassani-Sternberg, Giacomo Oliveira, George Coukos, Vincent Zoete
| Nature Verified
Correction to: Nature Biotechnology https://doi.org/10.1038/s41587-024-02232-0, published online 7 May 2024 In the version of the article initially published, there were errors in Extended Data Fig. 5e. One patient was erroneously omitted due to an inaccurate y-axis scale, and in the key “n = 17” has been corrected to “n = 12”. These corrections have been made to the HTML and PDF versions of the article.
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