Derek Wong on Muck Rack

Derek Wong

South Africa
As seen in: Color Research & Application, Nature, Wiley, Wiley Online Library, The American Journal of Human Genetics, The Daily Pennsylvanian, 34th Street Magazine, Hair News
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Articles

A pan-cancer compendium of 1,294 plasma cell-free DNA methylomes and fragmentomes enabling multicancer detection - Nature Cancer

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By Yong Zeng, Dor D Abelman, Althaf Singhawansa, Nicholas Cheng, Yuanchang Fang, Sasha C. Main, Emma J Bell, Wenbin Ye, Ping Luo, Samantha Wilson, Eric Y. Stutheit-Zhao, Derek Wong, Nadia Znassi, Kui Chen, Suluxan Mohanraj, Enrique Sanz-Garcia, Faiyaz Notta, anand Ghanekar, Philip Awadalla, Benjamin H. Lok, Michael Hoffman, Raymond Kim, Gelareh Zadeh, Scott V. Bratman, Mathieu Lupien, Trevor J. Pugh, Housheng Hansen He
| Nature
Abstract Cell-free DNA analysis via methylation and fragmentation profiling has advanced minimally invasive cancer detection; however, broader application has been limited by small cohorts and inconsistent data processing. Here we collated 1,074 cfMeDIP-seq profiles across 9 studies, comprising cancer samples from 11 cancer types, carriers of Li-Fraumeni syndrome and healthy controls. We developed a uniform computational workflow to mitigate technical and biological confounders across cohorts.
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Characterizing and engineering post-translational modifications with high-throughput cell-free expression - Nature Communications

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By Derek Wong, Martin Daniel-Ivad, Regina F Fernandez, Regina Lafuente Fernández, Fernando Tobias, Peter A. Faull, Emily P. Balskus, Ashty Karim
| Nature
Abstract Post-translational modifications (PTMs) are important for the stability and function of many therapeutic proteins and peptides. Current methods for studying and engineering PTMs are often limited by low-throughput experimental techniques. Here we describe a generalizable, in vitro workflow coupling cell-free gene expression (CFE) with AlphaLISA for the rapid expression and testing of PTM installing proteins.
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MIXX Up Your Playlist with NMIXX

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By Derek Wong
| 34th Street Magazine
Trust me when I say this—you need to check out NMIXX. NMIXX, JYP Entertainment’s newest Korean girl group, has had an interesting start to its career. If you’ve read Street’s “Best Albums of 2024,” you might be familiar with a snippet of their biography.
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