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D.R. Mani

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Articles by D.R. Mani

Integrative analysis of lung adenocarcinoma across diverse ethnicities and exposures

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By Shankha Satpathy, Natalie Clark, Yi-Ju Chen, Noshad Hosseini, Ya-Hsuan Chang, Yi Hsiao, Jonathan T. Lei, Francesca Petralia, Jin-Shing Chen, Yifat Geffen, David Heiman, Indranil Paul, Hanbyul Cho, Michelle Hollenberg, Giacomo B Marino, Kuen-Tyng Lin, Rahul Mannan, C. White, Joe Allen, Shayan C. Avanessian, M. Kane, Ashley Wolfe, Wenke Liu, Shankara Anand, Mong-Wei Lin, Moe Haines, Erik Bergström, Grant A. Hussey, Ginny Xiaohe Li, Deepak Mani, Hao Fang, Eric J. Jaehnig, Hasmik Keshishian, Kang-Yi Su, Yi-Jing Hsiao, Hsao-Hsun Hsu, Min-Shu Hsieh, Kuo-Hsuan Hsu, Simone Gohsman, John R. Thorup, Yamei Deng, Yo Akiyama, Eden Z. Deng, Eric Chen, Azra Krek, Rodrigo Espinoza, Weiping Ma, Daniel Charytonowicz, Robert Sebra, Jyun-Hong Lin, Yin-Chen Hsu, Kun-Chieh Chen, Yu-Tai Wang, Alexander J. Lazar, Mehdi Mesri, Xu Zhang, Karl R. Clauser, David Fenyö, Arul M. Chinnaiyan, Bing Zhang, Kelly V. Ruggles, Chelsea Newton, Pei Wang, Galen Hostetter, Gilbert S. Omenn, Chandan Kumar-Sinha, Ramaswamy Govindan, Paul K. Paik, Abhijit Parolia, QING LI, Avi Ma’ayan, Gad Getz, Saravana M. Dhanasekaran, Ana I. Robles, Gee-Chen Chang, Pan-Chyr Yang, Sung-Liang Yu, Hsuan-Yu Chen, Alexey I. Nesvizhskii, Steven Carr, D.R. Mani, Marcin Cieslik, Yu-Ju Chen, Michael Gillette, Chao-Wen Lu, Cheng-Hsiang Chu, Chia-Li Han, Chien-Yu Lin, Ching-Wen Chen, Chung-Hsien Lin, Hsiang-En Hsu, Jia-Jun Wu, Pei-Hsing Chen, Pei-Rong Huang, Wan-Chun Lai, Xu-Heng Chiang, Ya-Ling Chang, Yan-Ming Chen, Yi-Ling Chen, Yi-Wen Wang, Yi-Wei Lin, Yu-Cheng Chang, Yu-Ting Huang, Zhe-Rong Zheng, Akhilesh Pandey, Alexander Pilozzi, Alex Webster, Amanda G. Paulovich, Andrew Godwin, Barbara L Pruetz, Bart O. Williams, Brian Druker, Daniel Rohrer, Daniel Chan, Danail Petrov, Elizabeth Duffy, George Wilson, Grace Zhao, Jan Lubinski, Jasmine Huang, Jason M. Hafron, Jeffrey W. Tyner, John M. Koomen, Maciej Wiznerowicz, Marcin Domagalski, Meenakshi Anurag, Nathan Edwards, Paul D Piehowski, Qin Li, Rafael Fonseca, Rashna Madan, Ross Bremner, Sandra López Cerdá, Shuang Cai, Tao Liu, Thomas A. Bauer, Xiaojun Jing, Yuping Zhang, Zoran Andrić, Miloni Kinarivala, Brecca Miller, Alexi Monovoukas, Yan-Si Chen, Ze-Shiang Lin, Chang-Wei Yeh, Eunkyung An, Mathangi Thiagarajan, Chi-Ya Shen, Chien-Chia Lin, Hsing-Jui Tsai, Jing-Wei Lin, Juani Waniwan, Ki-Hok Liao, Sin-Ming Huang, Tai-Ching Lin, Wei-Tzu Chiu, Yuju Lien, Abdul Samad Hashimi, Adrij Mohan, Aniket Dagar, David Chesla, Diwakar Davaar, Iga Kołodziejczak, Kakhaber Zaalishvili, Karen A. Ketchum, Melissa Borucki, Negin Vatanian, Pamela Grady, Popovici Bogdan, Ratna R. Thangudu, Reese Crispen, Ronald Matteotti, Sandra L. Cottingham, Shirley Tsang, William W. Maggio, Yvonne Shutack
| Cell Press Verified
Keywords proteogenomics lung adenocarcinoma genomics mass spectrometry PTMs biomarkers smokers never-smokers CPTAC ICPC Introduction Lung adenocarcinomas (LUAD), the most prevalent subtype of non-small cell lung cancers (NSCLC), represent a significant global health challenge with marked geographical and epidemiological diversity in incidence and disease progression.1 Despite advances in targeted therapies and improved diagnostic techniques, LUAD continue to exhibit high mortality rates,2...
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An integrated proteomic portrait of prostate cancer progression

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By Jichang Zhang, Keith Rivera, Daniela Bossi, Federico Gianfanti, Simone Nicastri, Diana Gomes, Milos Matkovic, Marco Coazzoli, Simone Mosole, Federico Costanzo, Arianna Vallerga, Valentina Ceserani, Manuela Cavalli, Maya Virshup, Rajan Burt, Marco Bolis, Dorothea Ruthishauser, Anastasios Stathis, Holger Moch, Lukas Bubendorf, Andrea Cavalli, Eva Corey, Yuzhuo Wang, D.R. Mani, Steven Carr, Namrata D. Udeshi, Jean-Philippe Theurillat
| Cell Reports Verified
Keywords prostate cancer disease progression resistance to androgen receptor inhibition lineage plasticity protein phosphorylation ubiquitylation acetylation castration-resistant prostate cancer MAPK pathway Research topic(s) CP: Cancer Introduction Cancer follows a common disease trajectory in which transformed normal cells start to proliferate, form a local tumor, and metastasize to other organs.1 The latter is typically associated with fatal outcomes.
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Proteogenomic analysis of the CALGB 40601 (Alliance) HER2+ breast cancer neoadjuvant trial reveals resistance biomarkers

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By Eric J. Jaehnig, Aranzazu Fernández-Martínez, Matthew Holt, Jonathan T. Lei, Beom-Jun Kim, Yongchao Dou, Haoquan Zhao, Viktoriya Korchina, Richard A Gibbs, Harshavardhan Doddapaneni, Charles M. Perou, Lisa Carey, Ana I. Robles, Terry Hyslop, Yujia Wen, Azra Krek, Francesca Petralia, George Miles, Shyam M. Kavuri, Michael Gillette, D.R. Mani, Steven Carr, Bing Zhang, Matthew Ellis, Shankha Satpathy, Meenakshi Anurag, Tanmayi D. Vashist, LaTerrica Williams, Donna Marie Muzny, Linda McCart
| Cell Reports Medicine Verified
Clinical trial details The study design and pCR (pathological complete response) outcomes of the CALGB 40601 trial (NCT00770809) have been previously published.4 In this study, a total of 305 untreated women newly diagnosed with stage II and III HER2-positive breast cancer were randomly assigned to different treatment groups.
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Improving the Identification of Therapeutic Vulnerabilities in Breast Cancer

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By Steven Carr, Michael Gillette, Lindsay Brownell, D.R. Mani
| Onco’Zine Verified
Researchers at Baylor College of Medicine, the Broad Institute of MIT, and Harvard have applied powerful proteogenomics approaches to better understand the biological complexity of breast cancer. Matthew Ellis MD, BChir, BSc., Ph.D., FRCP, serves as director of the Lester and Sue Smith Breast Center at Baylor. He is a world-renowned clinician and researcher of the molecular profiling of breast cancer. Ellis is a native of the United Kingdom.
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