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Articles by Duc Phan
Umbilical cord blood cell transcriptional and methylation signatures at birth are associated with BPD development and chorioamnionitis: a pilot study
Abstract Bronchopulmonary dysplasia (BPD) is the most common respiratory disease in preterm infants born at less than 28 weeks gestation. Most existing clinical prediction models for BPD show limited accuracy in predicting BPD development when validated using external data, stressing the need for novel biomarkers to identify at-risk infants for early and effective interventions.
Humans with function-disrupting variants in the myostatin gene (MSTN) have increased skeletal muscle mass and strength, and less adiposity
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Abstract Myostatin negatively regulates skeletal muscle size in multiple species, and therefore, myostatin blockade has been therapeutically explored to promote muscle growth in humans, including to counter the muscle loss seen in obese humans using GLP1R agonists.
By Joseph L. Herman, Peter Dornbos, Karl Landheer, Benjamin J. Geraghty, Duc Phan, Jason Mastaitis, Luca A. Lotta, Goncalo Abecasis, Aris Baras, Judith Altarejos, Mark W. Sleeman, Olle Melander, Tea Shavlakadze, George D. Yancopoulos, Jonas Bovijn, Jonathan Marchini, David Glass, Marc A. Egerman, Mary Germino, Johnathon R. Walls, Malmö Diet
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Nature
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Effectiveness of Adalimumab Biosimilars and Originator for Psoriasis
Importance The uncertainties about the real-world effectiveness of adalimumab biosimilars limit their widespread adoption for psoriasis. Objective To compare the effectiveness of adalimumab biosimilars Amjevita and Imraldi with Humira for psoriasis.
Training by Pairing Correlated Samples Improves Deep Network Generalization
1. Introduction In recent years, Deep Neural Networks (DNNs) and Machine Learning (ML) have had a wide range of successes across many application domains [1,2,3,4,5,6,7]. In computer vision, DNNs, especially Convolutional Neural Networks (CNNs), excel at tasks such as image classification, object detection, and semantic segmentation [8,9,10].
Traffic Congestion and Safety: Mixed Effects on Total and Fatal Crashes
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Emergent Macroscopic Bistability Induced by a Single Superconducting Qubit
Popular Summary The recently introduced notion of macroscopic phases in microscopic quantum systems broadened the scope of phase transitions from condensed matter to quantum optics. First-order dissipative phase transitions specifically, have been predicted to be possible to realize in situations where a single qubit strongly interacts with many cavity photons in what has been called the photon blockade breakdown.
Energies | Free Full-Text | Hydrothermal but Not Mechanical Pretreatment of Wastewater Algae Enhanced Anaerobic Digestion Energy Balance due to Improved Biomass Disintegration and Methane Production Kinetics
3. Results and Discussion 3.1. Algae Cultivation in Wastewater Ponds For the project period from 20 June to 25 July, the average algal biomass gross productivity was 66 ±15 g m−2 day−1, and the net productivity was 57 ± 16 g m−2 day−1 (Figure 1A). Over this period, the average 24 h solar insolation and temperature were 313 ± 42 W m−2 and 15.7 ± 1.1 °C, respectively, contributing to the high productivity.
Drug survival and safety of biosimilars and originator adalimumab in the treatment of psoriasis: a multinational cohort study
Data analysis Establishing analytical cohort This study will implement the prevalent new-user cohort design with the following steps in delineating the analysis cohort. Separate pairs of biosimilar and matched originator cohorts will be identified for each biosimilar (ie, Amgevita vs Humira, Hyrimoz vs Humira, Imraldi vs Humira, etc). Primary cohort formation: all eligible participants, including biosimilar and originator users, will be identified and included in the primary cohort.
Biosimilars for the Treatment of Psoriasis
Key Points Question What is the effectiveness and safety of biosimilars compared with originator biologics for the treatment of patients with psoriasis? Findings This systematic review of 14 randomized clinical trials and 3 cohort studies found that there was no clinically or statistically significant difference in efficacy and safety between biosimilars of adalimumab, etanercept, infliximab, ustekinumab, and originators for the treatment of patients with psoriasis.
Impact of nitrogen and phosphorus on the growth and microcystin‐related gene expression of Microcystis aeruginosa PCC 7806
The growth of Microcystis aeruginosa is impacted by nitrogen and phosphorus levels with no clear association with microcystin production. 1 INTRODUCTION In the past decade, harmful algal blooms (HABs) have increased in their frequency and intensity, resulting in a rise in the number of public health concerns being reported (Hallegraeff, 2003). Cyanobacterial blooms are among the most common HABs found in freshwaters such as rivers, lakes, and creeks.
Retail : 3 bonnes raisons de miser sur la réalité virtuelle
Chronique de Duc Phan UCOPIA 11/02/19 11:47 Twitter LinkedIn Facebook Viadeo Email Alors que les points de vente ont subi une perte de vitesse drastique avec l’explosion du e-commerce et la montée en puissance du m-commerce, les nouvelles technologies offrent de belles cartes à jouer à un retail en pleine mutation.
Le Wi-Fi, nouveau canal de communication pour les lieux accueillant du public
Chronique de Duc Phan UCOPIA 11/02/19 10:44 Twitter LinkedIn Facebook Viadeo Email Le Wi-Fi devient un levier de la transformation digitale et le vecteur d’une valeur ajoutée pour les utilisateurs, les marques mais aussi les lieux accueillant du public. Dans un contexte où la digitalisation conquiert toutes les sphères de la société, chaque nouvelle innovation technologique devient créatrice de valeur.
Induction of Mesoderm and Neural Crest-Derived Pericytes from Human Pluripotent Stem Cells to Study Blood-Brain Barrier Interactions
Highlights • Mesoderm and neural crest-derived pericytes (PCs) from hPSCs termed mPCs and ncPCs • mPCs and ncPCs express general and brain-specific pericyte genes • mPCs and ncPCs associate with and promote barrier properties of endothelial cells • WNT is important, but not necessary for neural crest-derived PC specification Summary In the CNS, perivascular cells (“pericytes”) associate with endothelial cells to mediate the formation of tight junctions essential to the function of the...
Real-Time Quantitative PCR Measurements of Fecal Indicator Bacteria and Human-Associated Source Tracking Markers in a Texas River following Hurricane Harvey
Hurricane Harvey has caused unprecedented devastation to huge parts of southeastern Texas, particularly damaging the wastewater infrastructure resulting in release of sewage contamination into environmental waters. The purpose of this study was to conduct a preliminary assessment of fecal indicator bacteria (Escherichia coli and enterococci) and human-associated fecal genetic markers (human-associated Bacteroidales), measured using qPCR assays, across a Texas river impacted by Hurricane Harvey.
Saigon Barbershops: Seven Of The Sharpest
We’ve compiled a list of eight of the sharpest men's barbershops in Ho Chi Minh City. If you're not sure where to go for a fresh fade, give one of these a try. With an average local temperature of 30 degrees, good grooming is essential to beat the tropical Saigon heat. Luckily, a growing number of barbers have got our backs (and sides).
Modelling the Relationships between Train Commuters’ Access Modes and Traffic Safety
Walking, cycling, and feeder bus/tram for first- and last-mile (FLM) train access are often considered to have better health benefits, lower cost, and less environmental impacts than driving. However, little is known about the road safety impacts of these FLM access modes, particularly at a network level. This paper aims to investigate the impacts of train commuters’ access modes on road safety in Victoria, Australia.
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