Skip To Main Content
Franco Izzo on Muck Rack

Franco Izzo

As seen in: Nature, Genome Biology, BioRxiv, Cell Reports, Cell Stem Cell, Cell Press, Texas Medical Center
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Franco

Contact Franco, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Single-cell mapping of regulatory DNA-protein interactions

|
By Wei-Yu Chi, Sang-Ho Yoon, Evrim Goksel, Levan Mekerishvili, Joe Pelt, Yiyun Lin, Tamara Prieto, John Zinno, Saravanan Ganesan, Catherine Potenski, Franco Izzo, Dan A. Landau, Ivan Raimondi
| Cell Press Verified
ResourceOnline nowOpen access Affiliations & Notes 1Sandra and Edward Meyer Cancer Center, Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA 2New York Genome Center, New York, NY, USA 3Physiology, Biophysics and Systems Biology Graduate Program, Weill Cornell Medicine, New York, NY, USA 4Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA 5Tisch Cancer Institute, Icahn School of Medicine at...
Open in Who Shared Issue with article?

T follicular helper cells transiently unlock a plasticity state in germinal centre B cells during the humoral immune response - Nature Cell Biology

|
By Laurianne Scourzic, Franco Izzo, Alexander Polyzos, Christopher R Chin, Coraline Mlynarczyk, Min Xia, Wendy Béguelin, Matthias Stadtfeld, Ari M Melnick, Ioanna Tsialta, Abigail Lidoski
| Nature Verified
Abstract During the germinal centre (GC) reaction, mature B cells undergo rapid and reversible phenotypic shifts that are essential for adaptive immunity. Here we report that GC B cells, unlike other mature B cells, transiently acquire a unique epigenetic plasticity, demonstrated by their enhanced capacity to reprogram to induced pluripotent stem cells. This plasticity depends on T follicular helper (TFH) cells and is not due to increased proliferation or MYC activation.
Open in Who Shared Issue with article?

Mapping Genotypes to Chromatin Accessibility Profiles in Single Cells

|
By Franco Izzo
| Texas Medical Center
Abstract In somatic tissue differentiation, chromatin accessibility changes govern priming and precursor commitment towards cellular fates1-3. Therefore, somatic mutations are likely to alter chromatin accessibility patterns, as they disrupt differentiation topologies leading to abnormal clonal outgrowth. However, defining the impact of somatic mutations on the epigenome in human samples is challenging due to admixed mutated and wild-type cells.
Open in Who Shared Issue with article?
See all 14 articles