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ArticleVolume 6, Issue 12102478Open access 1Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX, USA 2Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA 3Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA 4Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA Publication History: Received October 23, 2023; Revised...
Keywords lung adenocarcinomas EGFR placental-type alkaline phosphatase antibody drug conjugate Introduction Surface proteins expressed in cancer cells, with restricted expression in normal tissues, are highly sought after for treatment modalities including antibody-drug conjugates (ADCs) and cell therapies.1,2,3 Oncogenes including KRAS-, epidermal growth factor receptor (EGFR)-, or human epidermal growth factor receptor 2 (HER2)-transformed cells induce significant alterations of surface...
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