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Lung adenocarcinoma surfaceome remodeling with EGFR inhibitors uncovers placental alkaline phosphatase as a target for combination therapy
Keywords lung adenocarcinomas EGFR placental-type alkaline phosphatase antibody drug conjugate Introduction Surface proteins expressed in cancer cells, with restricted expression in normal tissues, are highly sought after for treatment modalities including antibody-drug conjugates (ADCs) and cell therapies.1,2,3 Oncogenes including KRAS-, epidermal growth factor receptor (EGFR)-, or human epidermal growth factor receptor 2 (HER2)-transformed cells induce significant alterations of surface...
Vesicle-mediated mitochondrial clearance presents an actionable metabolic vulnerability in triple-negative breast cancer
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ArticleVolume 6, Issue 12102478Open access 1Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX, USA 2Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA 3Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA 4Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA Publication History: Received October 23, 2023; Revised...
By Jody V. Vykoukal, Yihui Chen, Mingxin Zuo, Riccardo Ballarò, Monica J. Hong, Hiroyuki Katayama, Ehsan Irajizad, Ranran Wu, Ricardo A. León-Letelier, Jennifer B. Dennison, Angelica Gutierrez, Adriana Paulucci-Holthauzen, Timothy Thompson, Leona Rusling, Yining Cai, Fu Chung Hsiao, Soyoung Park, Banu Arun, Samir Hanash, Johannes F Fahrmann, Hansini Krishna, Daniela B. Rodriquez-Perera
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Cell Reports Medicine
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SHS Web of Conferences 218, 04020 (2025) Study on the Causes and Consequences of Greenwashing at Valin Steel * School of Management, University of Shanghai for Science and Technology, 200093 No. 516, Jun gong Road, Yangpu District, Shanghai, China * Corresponding author: 2213530201@st.usst.edu.cn Abstract Against the backdrop of accelerated global ESG investment and stricter carbon neutrality policies, the steel industry faces dual pressures of green transformation and economic benefits.
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