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ArticleVolume 6, Issue 12102478Open access 1Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX, USA 2Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA 3Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA 4Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA Publication History: Received October 23, 2023; Revised...
Abstract Selective autophagy of mitochondria is known to promote survival and progression of cancer cells in various malignancies including triple-negative breast cancer (TNBC). Here, we aimed to identify the essential metabolic adaptations that support mitochondrial quality control with the goal to uncover actionable metabolic vulnerabilities with therapeutic potential.
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