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Articles

RNA structure programs endogenous ADAR for precise and efficient editing

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By Deli Song, Gexing Liu, Wei Zhang, Jiwu Ren, Xuanxuan Jin, Yanglong Sun, Zexuan Yi, Shiwei Qiu, Huixian Tang, Zongyi Yi, Lu Wang, Zhiwei Lu, Jiangping Xie, haoyue liu, Gangbin Tang, Yongjian Zhang, Ying Yu, Pengfei Yuan, Ying Liu, Wei Xiong, Wensheng Wei
| Cell Press Verified
Keywords ADAR RNA editing LEAPER circular RNA AlphaFold3 engineered ADAR-recruiting RNAs arRNAs AATD Usher syndrome DMD Get full text access Log in, subscribe or purchase for full access. References 1. Song, J. ∙ Zhuang, Y. ∙ Yi, C. Programmable RNA base editing via targeted modifications Nat. Chem. Biol. 2024; 20:277-290 2. Abudayyeh, O.O. ∙ Gootenberg, J.S. ∙ Franklin, B. ... A cytosine deaminase for programmable single-base RNA editing Science. 2019; 365:382-386 3.
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Long-term reversal of Duchenne muscular dystrophy via circular arRNA-guided exon skipping in monkeys and humans

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By Wenting Guo, Huixian Tang, Zongyi Yi, Ting Zhang, Pengfei Yuan, Cuijin Wang, Shuaiwei Ren, Xiwen Chang, Jiwu Ren, Wei Tang, Wenjie Sun, Jie Liu, Ying Yu, Zhiwei Lu, Hongyan Shen, Zexuan Yi, Yanxia Zhao, Gangbin Tang, Junyuan Han, Wenzhi Zhang, haoyue liu, Xueqing Sun, Yongjian Zhang, Cui Zhang, Yuming Wu, Feng Han, Yichao Xu, Liang Qu, Xinyan Sun, Jiwen Wang, Weizhi Ji, Yongchang Chen, Wensheng Wei
| Cell Press Verified
Keywords Duchenne muscular dystrophy DMD circ-arRNA LEAPER ADAR RNA editing exon skipping AAV adeno-associated virus muscle degeneration nonhuman primate model NHP model DMD patient Get full text access Log in, subscribe or purchase for full access. References 1. Crisafulli, S. ∙ Sultana, J. ∙ Fontana, A. ... Global epidemiology of Duchenne muscular dystrophy: an updated systematic review and meta-analysis Orphanet J. Rare Dis. 2020; 15:141 2. Mendell, J.R. ∙ Shilling, C. ∙ Leslie, N.D. ...
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Computer Science > Artificial Intelligence

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By Yiwen Li, haoyue liu, Zhichao Wang
| arxiv.org
arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs.
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