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Articles by Harrison Lee
Lethal permeabilization of host bacteria to small-molecule compounds during phage penetration
Abstract Tailed phages (Caudoviricetes) inject their double-stranded linear genomic DNA across the bacterial envelope to initiate infection. During this DNA entry process, ionic fluxes and membrane depolarization may occur, potentially leading to increased vulnerability to antibiotic molecules. Here, we report that phage DNA translocation combined with certain small molecules triggers rapid and phage-specific cell permeabilization leading to bacterial growth arrest.
Branding In Sportstech: Why Brand Is Now A Strategic Advantage
Potter Clarkson are most popular: with Senior Company Executives, HR and Finance and Tax Executives in United Kingdom with readers working within the Accounting & Consultancy and Law Firm industries Sportstech is moving fast. New platforms, devices, data tools and fan experiences are reshaping how sport is played, watched and commercialised. From wearable performance technology and AI-driven analytics to immersive fan engagement and smart venues, innovation is no longer a differentiator.
Glistening High Notes and High-Stakes Haydn
Kicking off the New Year in Jordan Hall this past Friday, the Handel + Haydn Society’s ambitious “musical feast of Mozart + Haydn” impressed as largely successful. In a humorous introduction, Nancy and Richard Lubin Chair cellist Guy Fishman led us to anticipate Concertmaster Nosky’s jumping off “the edge of her seat” during Haydn’s Symphony No. 44 Trauer, as well as the ensemble’s premiere of Telemann’s unfrequented masterwork, Ino.
Sportstech and the IP frontier: how do you protect sportstech innovation in the digital age?
In 2025, the global sports industry stands at a pivotal crossroads. While traditional revenue streams remain robust, a recent report from Morgan Stanley shows that the industry could unlock an additional 25% in annual revenue simply by closing its digital adoption gap. This adds up to a staggering $130 billion. As Intellectual Property (IP) lawyers who specialise in sportstech, we know unlocking this opportunity this is not just about advising clients on the value of technology.
GHB, Chemsex and Chemical Submission: Investigating the Role of Sexuality on Victim Empathy and Blame Attribution in Drug-Facilitated Sexual Assault against Men
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Paper page - RLAIF: Scaling Reinforcement Learning from Human Feedback with AI Feedback
Papers Published on Sep 1 · Featured in Daily Papers on Sep 4 Abstract Reinforcement learning from human feedback (RLHF) is effective at aligning large language models (LLMs) to human preferences, but gathering high quality human preference labels is a key bottleneck. We conduct a head-to-head comparison of RLHF vs. RL from AI Feedback (RLAIF) - a technique where preferences are labeled by an off-the-shelf LLM in lieu of humans, and we find that they result in similar improvements.
Game Recap: Winnipeg Jets vs. Nashville Predators
The Winnipeg Jets can hear the countdown ticking away. The playoffs are fast approaching, and the Jets are fighting tooth and nail to hang on to a post-season berth. The last few months have been quite rocky, with Hellebuyck looking mortal and the offense forgetting how to score. It all set up a crucial road match-up with the Nashville Predators, the one team Winnipeg is trying to fend off for the second wild card. Could the Jets rally for a massive win?
Game Recap: Winnipeg Jets vs. Arizona Coyotes
The vibes are not with the Winnipeg Jets right now. The team and fanbase seem to be in varying levels of disengaged. A mixture of poor finishing, a lack of high-danger chance creation, and puzzling line-up choices have left Winnipeg with its back to the wall. Against a resurgent Arizona Coyotes team, the Jets were gifted a golden opportunity for a bounce-back effort. What unfolded was quite a lot less reassuring… Winnipeg kicked the game off looking slower than expected.
Game Recap: Winnipeg Jets vs. Anaheim Ducks
Watching the Anaheim Ducks must be excruciating for their fanbase. I know it’s all for the good of Bedard, but sweet mother of mercy are they darn near unwatchable. Not so long ago, the Winnipeg Jets were just as painful to suffer through. They’ve been better this season, though their finishing ability has apparently abandoned them at the worst possible time. Surely a match-up against the beleaguered Ducks would spark the team to glory…right?
Game Recap: Winnipeg Jets vs. LA Kings
Despite 2 recent wins, one would hardly be inclined to say the Winnipeg Jets are doing well right now. The team is barely holding on by a thread, with the season and fanbase on life support. With 8 or 9 games left in the season, every single point is going to be critical. A road match-up against the LA Kings looked like a loss from the beginning. If you had the same thought, it’s hard to say you were disappointed.
Game Recap: Winnipeg Jets vs. San Jose Sharks
The Winnipeg Jets are coming to the end of their season, and it sure feels like that end will be game 82. The playoff hopes are rapidly fading, replaced with the reality of Nashville and Calgary steadily gaining ground on the Jets. It is so Winnipeg to squander one of the best season starts in recent memory during the home stretch. These last few months should have been a victory lap for a top-3 divisional finish.
GDT: Winnipeg Jets vs. San Jose Sharks
Time: 9:30 PM CST Channel: TSN3 Radio: CJOB Apologies for the late thread folks, the hour itself is late in these parts and I forgot to throw this up before the Winnipeg Jets do whatever it is they do against the San Jose Sharks. The game hasn’t kicked off to the best of starts, but maybe Winnipeg will surprise us! Drop your score predictions below.
American Dream: The Cougar relives UH’s decade in the AAC
In 10 years as a member of the American Athletic Conference, the University of Houston has participated in well over 3,000 sporting events across 17 varsity sports. In that time, UH has won 41 conference titles (second-most in the conference), made 128 NCAA postseason appearances, and won six individual National Championships. The decade also saw the opening of TDECU Stadium in 2014, and the old Hofheinz Pavillion resurrected into the often-rowdy Fertitta Center in 2018.
The Cougar relives UH's decade in the AAC
In 10 years as a member of the American Athletic Conference, the University of Houston has participated in well over 3,000 sporting events across 17 varsity sports. In that time, UH has won 41 conference titles (second-most in the conference), made 128 NCAA postseason appearances, and won six individual National Championships. The decade also saw the opening of TDECU Stadium in 2014, and the old Hofheinz Pavillion resurrected into the often-rowdy Fertitta Center in 2018.
Supercar Collector Delivers Pizza With Bugatti Chiron, McLaren 765LT, And McLaren Senna
For many young car enthusiasts, delivering pizza is an ideal job because it allows them to spend a lot of time behind the wheel. Typically, this profession also involves a limited selection of economic choices for cars. So when an established enthusiast decides to take to this job in a Bugatti Chiron, it certainly isn't like any normal delivery.
The Holden Maloo Ute Remains One Of The Most Fun Quirky Cars North America Never Had Original
Throughout automotive history, there are many cars that seem to fail with consumers, despite succeeding with enthusiasts. Chevrolet's El Camino is one such example. Classified as a 'ute', the hybrid type combined a low-to-the-ground platform, with pick-up truck utilities. These utes did not survive the North American market. But thanks to Holden (GM's Australia division), the Australian market offers a very different story.
Returning This 1969 Chevrolet El Camino Engine To Its Former Glory
When discussing American classic cars, most casual enthusiasts likely think of the conventional muscle car rather than a ute pick-up truck. There is one exception to this. Whether one has seen Drake and Josh break down in the middle of nowhere, or Jesse Pinkman's choice of vehicle in Breaking Bad, these television references only contribute to the Chevrolet El Camino's popularity among enthusiasts looking to restore a more obscure American classic.
Watch This YouTuber Get Up Close And Personal With The New Lamborghini Revuelto
When it comes to Italian supercars, Ferrari and Lamborghini are likely the two brands that first come to mind. They're both world-renowned, and the former is much older. In The Stradman's latest video, James expresses the significance of the names of what he considers his favorite manufacturer, Lamborghini. Be it the Countach, Diablo, Murcielago, or Aventador, many of Lamborghini's household models are distinct to their respective generations of enthusiasts.
Rescuing A One-Owner Chevrolet Biscayne Barn Find From 1959
When it comes to classic American muscle cars, Chevrolet's Impala remains a household name. This is because up until several years ago, the Impala's production seemed to survive within modern car markets. Even after its discontinuation, it's still easy for enthusiasts to remember the Impala's evolution, which long surpassed the lesser-known Biscayne. At first glance, an Impala and Biscayne in 1959 appear like twins.
The 2023 Goodguys Spring Nationals Is A Classic American Car Enthusiast's Dream Original
Over the last 80 years, the American car industry has evolved immensely. Much of its historic models could never enter production again and are best not replicated. Yet, even the glory of the original classics continues to decay in the many farms and scrapyards. But for all the restored survivors still preserved in peak condition, there is almost no better way to celebrate these cars than at the Goodguys Spring Nationals Car Show.
Exploring 2 Midwestern Junkyards For Classic Car Treasure
It isn't uncommon for older, unreachable cars to possess enthusiast-preferred character. With time, this favored selection continues piling up and withering away in scrapyards. But these yards are also valuable grounds for the parts needed to restore these classic cars. Such is the case with IowaClassicCars' latest find in a 1963 Chevrolet Impala Wagon. Given the conditions of scrapyard discoveries, venturing out to retrieve this finding was a long one.
Watch These 2 Top Ford Mustangs Double Team A Porsche GT3 RS
When it comes to an individual's favorite car, every enthusiast has their own opinion. Some will happily address theirs in competition with others' choices. The best way to settle these debates is undoubtedly on the pavement where performance speaks for itself. Such is the case when top-of-the-line models like Porsche's 911 and Ford's Mustang face off on the 1/4 mile. This opposition is exactly what car YouTuber Sam CarLegion orchestrated in his latest drag racing video.
This YouTuber Gets A Look Inside The Stradman's Enthusiast-Filled Supercar Garage
The automotive YouTuber, TheStradman, has one impressive collection of supercars. Whether it's a new C8 Corvette Z06, a Lamborghini Aventador, or a Bugatti Veyron, there's no shortage of great content. He also frequently collaborates with other automotive YouTube channels like Shmee150, Streetspeed717, and many others. With that in mind, popular JDM YouTuber effspot pays TheStradman a visit and gets the rare opportunity to drive a Ferrari in TheStradman's collection.
This YouTuber Organizes His Classic Car Junkyard With Some Brute Force
When it comes to salvage yards, even car enthusiasts may find it difficult to imagine that such rusty shells and mangled accidents will ever move again. It's likely a different story for the junkyard owners who are responsible for organizing their valuable parts inventory. Car YouTuber DezzysSpeedShop is no exception. As a yard owner himself, there was often a need to move his inventory around to access various classic cars.
This Mustang GT350-H Breaks Down Shortly After Visiting Shelby American Headquarters
Of all the tuning companies attached to auto manufacturers, it's difficult to determine any brand that comes close to possessing the recognition and history that Shelby American has with Ford. Shelby did help Dodge with their GLH Omni in the 1980s, but it was really their work with the blue oval that cemented Caroll Shelby's name in the automotive industry.
Watch This Ford Mustang GT Destroy A Jaguar F-Type That's Nearly Double Its Price
It's been 15 years since Ford put Land Rover and Jaguar up for another adoption. Ford as a brand itself continues to dominate in volume sales and performance with the all-powerful Mustang. It seems Jaguar has been rather left behind and that includes at the drag strip. Automotive YouTuber Cars with Pilot Tseno recently documented what happens when a Jaguar F-Type S drag races a Ford Mustang on the 1/4 mile.
Attempting To Resurrect Multiple Mustangs From A Maryland Junkyard
A reoccurring theme in automotive culture is that the character of a car often succeeds at the expense of reliability. Yet, a performance vehicle's purpose is to drive hard, rather than last long. So it's not surprising one may find a junkyard trove of Ford Mustangs. The surprise rather comes from what still lives in these junkyards.
The Auto Archaeologist Discovers A Farmyard Full Of Mopar Muscle Cars
Home Muscle Cars The Auto Archaeologist Discovers A Farmyard Full Of Mopar Muscle Cars Ryan Brutt heads to a St. Louis treasure trove of old Chryslers for those looking for an ambitious old-school project car. No matter the build quality, every car eventually breaks. Some are easier to fix if parts and repair prerequisites are plentiful. Though oftentimes, it's more economical for the average consumer to move on with their next vehicle.
Why Doug DeMuro Thinks The Ferrari 360 Challenge Stradale Is One Of The Coolest Modern Ferraris
Those who have watched Doug DeMuro since the beginning may remember the Ferrari 360 he first reviewed and owned. While that car is long gone, it seems Doug found a much more special 360 to talk about: A 2004 Ferrari 360 Challenge Stradale. Read on to find out why Doug thinks this is one of the "coolest modern Ferraris".
Further Misadventures With Buyers, Sellers, And Turo Scammers Keep This Automotive YouTuber Busy
Home Car Culture Further Misadventures With Buyers, Sellers, And Turo Scammers Keep This Automotive YouTuber Busy Tyler Hoover is back in the Car Wizard's shop with a sale to LegitStreetCars, an apology to the Citroën seller, and a warning for Turo renters. Hoovies Garage may be the dumbest automotive channel on all of YouTube according to Tyler Hoover himself. However, Hoovie proves to run a responsible channel both in the midst of rental scams and his own mistakes.
Family Harmony
Family Harmony. What an interesting concept. For some it is a default setting and something that isn't even thought about it as a concept. For others it's a laughable idea. Something that people write about in fairy tales but could never materialise into reality. Recently I've been thinking about it more as I get older. In this funny transitory place where I am an adult yet not fully independent. Living at home yet barely at home.
Sin City Muscle Cars Is A Garage Suite Of The Most Incredible Mustang Restorations
The limited life expectancy of a classic car should not surprise any enthusiast. This is why restoration garages like Sin City Muscle Cars are so important. Thanks to them, a handful of classic American muscle cars will remain in good care for years to come. Sin City's limited collection is not currently available for a public showcase. Yet, car enthusiast and YouTuber JC Fernandez recently documented an insight into the contents of their garage.
A Life with Anxiety
My journey navigating severe anxiety TW: Anxiety, Panic attacks In a heated moment, my partner said to me in tears, "You aren't the same person you used to be.". It caught me completely off guard. I remember being in shock, reeling from a dagger-like sentence striking deep in a part of my heart I didn't know existed. It had been 5 months since I had been treated for debilitating symptoms of severe anxiety.
We save those we can
Recently, I finished a book called Anxious People by Fredrik Backman. And through all the beautiful prose, simple yet deeply emotive statements and extended metaphors, a phrase caught hit home. Throughout my life, I have always blamed myself for not doing enough. For not being able to be there for friends when they needed it. For not being able to support my loved ones in the best way. For not being able to catch my own self before I fall into hardship.
Visualizing orthogonal RNAs simultaneously in live mammalian cells by fluorescence lifetime imaging microscopy (FLIM) - Nature Communications
Abstract Visualization of RNAs in live cells is critical to understand biology of RNA dynamics and function in the complex cellular environment. Detection of RNAs with a fluorescent marker frequently involves genetically fusing an RNA aptamer tag to the RNA of interest, which binds to small molecules that are added to live cells and have fluorescent properties. Engineering efforts aim to improve performance and add versatile features.
The Heart of Longboarding
Yesterday a piece of my heart shattered. I was skating after work in the city on the way to dinner with some friends when it started raining. Nothing too crazy, just enough to extend your brake times by a few seconds and make your wheels muddy. About an intersection away from my destination I waited at the traffic lights. It was one of the busiest pedestrian intersections in the lead up to Christmas.
Georgetown University Establishes Racial Justice Institute, Hires 3 Co-Leaders
Georgetown University has established a new interdisciplinary institute to address racial injustice and racial inequities within society, fulfilling one of a series of commitments the university made to combating racial inequality in 2016. The Racial Justice Institute will promote interdisciplinary work on race, equity and action by serving as a hub for research and scholarship across various departments, according to a community-wide email sent Feb. 22.
Unsure of Spring Season, Baseball Team Organizes Player-Led Practices
Georgetown University’s baseball team players have organized student-run practices after the university did not clear them because of COVID-19 precautions. Georgetown is the only school in the Big East Conference that has not cleared its baseball team to compete this season. The university has not yet decided whether the baseball team will be permitted to compete in the spring 2021 season, which is scheduled to start Feb. 19, according to a university spokesperson.
GIWPS Hosts Event Series on Findings of Gender Equality Report
The Georgetown Institute for Women, Peace and Security launched a five-part event series on advancing gender equality, which aims to expand upon and share findings from a GIWPS research report highlighting the key issues facing women currently. The series kicked off Jan. 28 and will cover ongoing obstacles to achieving international gender equality, with monthly events scheduled throughout the spring 2021 semester.
Georgetown Students Pestered by Phishing Scams
Phishing attempts promising job opportunities are circulating through Georgetown University’s email system, according to the university’s Chief Information Officer Judd Nicholson in a systemwide message Sept. 22. In many of the phishing emails, scammers posing as administrators offer students fraudulent university employment. In his message, Nicholson urged students to ignore the emails and not interact with them in any way.
Georgetown Student Tenant Association To Revive Operations Amid Student Housing Difficulties
The Georgetown Student Tenant Association plans to enhance its operations to aid students experiencing housing uncertainty and grappling with untenable leases because of the COVID-19 pandemic. After Georgetown University decided to hold the fall semester online, upending many students’ fall plans, students living in the Georgetown neighborhood reported financial and housing difficulties. Some were unable to break leases or receive discounts on rent.
Latest Class of GUSA Senators Breaks Records for Black, Female Representation
Georgetown University undergraduates elected a majority female student senate for the first time in history last week, marking what many Georgetown University Student Association officials hope is a permanent transition to a more diverse and inclusive student government. Polls closed for the GUSA Senate elections Sept. 19 after a contentious and unorthodox campaign cycle.
Indoor Application of Emerging Photovoltaics - Progress, Challenges and Perspectives
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Association between hidradenitis suppurativa, depression, anxiety, and suicidality: A systematic review and meta-analysis
Background Previous studies found conflicting results about whether hidradenitis suppurativa (HS) is associated with depression or anxiety. Objectives To determine the relationship of HS with depression and anxiety.
Former Chiefs of Staff Stress the Importance of Information in Handling National Crises
Understanding and distributing updated and objective information is crucial during crises, former White House chiefs of staff said in a virtual roundtable. The conversation focused in particular on the COVID-19 pandemic and how President Donald Trump’s administration has approached the crisis. Mick Mulvaney (SFS ’89) spoke about his time advising Trump in the early stages of the pandemic, and the rest of the panel told stories from their own experiences serving in the White House.
NFL Players Read Mean Tweets About Themselves
"Michael Strahan's teeth are having a middle school dance, where the boys stand on one side of the room and the girls stand on the other."
Mike Leach Finally Weighs In On Guns In America, And His Take Is Pure Gold
Mike Leach is by far one of the most interesting coaches in all of football. He thinks he’s a pirate for shit’s sake. You could sit and listen to him talk for hours. He coaches and speaks with a reckless abandon, which is most likely due to him downing a handle of Jack Daniels before the games. Whenever you’re around him, you’re just waiting for the next pure, solid gold quote. So when he was asked to give his take on gun violence, he was more than happy to provide us with some A+ entertainment.
Bristol Motor Speedway Preps For Va. Tech-Tennessee By Ordering Half A Million Beers
======= ======= ====== ====== ====== ===== ==== ====== ====== ===== ==== ======= ======= ====== ====== ====== ===== ==== ====== ====== ===== ==== Saturday night should be a fun one in Bristol. Virginia Tech and Tennessee fans will pack Bristol Motor Speedway for the first ever college football game played at a racetrack. 150,000 people are expected to be in attendance. To make sure everyone in the stadium is well hydrated, BMS ordered quite a bit of beer.
Parks And Rec’s Chris Pratt Raps “Forgot About Dre” And Fucking Nails It
Thanks man, I really hope so. Let me know when Devry Guy lets you out of his trunk and I’ll buy you a beer! 14 Log in to reply or vote on comments
Organic photovoltaic cell - a promising indoor light harvester for self-sustainable electronics
Photovoltaic cells are attracting significant interest for harvesting indoor light for low power consumption wireless electronics such as those required for smart homes and offices, and the rapidly-growing Internet of Things. Here, we explore the potential of solution processable, small molecule photovoltaic cells as indoor power sources.
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