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Trajectory changes of symptom clusters in patients with concurrent chemoradiotherapy for cervical cancer: a prospective longitudinal study
Abstract Objective: To identify the trajectory changes of symptom clusters during concurrent chemoradiotherapy in cervical cancer patients and to explore the heterogeneity of symptom experience among different patients. Methods: From June 2024 to June 2025, 150 patients with cervical cancer undergoing concurrent chemoradiotherapy at a tertiary-level hospital in Anhui Province were selected as the study subjects.
Evaluation of the Choroid Plexus Epithelium Inflammation TLR4/NF‐κB/NKCC1 Signal Pathway Activation in the Development of Hydrocephalus
AQP aquaporin CPE choroid plexus epithelium CSF cerebrospinal fluid IF immunofluorescence IL-18 interleukin 18 NF-κB nuclear factor-kappa B NKCC1 Na+/K+/2Cl − cotransporter 1 PDTC pyrrolidine dithiocarbamate SPAK serine–threonine STE20/SPS1-related, proline-alanine-rich kinase TLR4 toll-like receptor 4 TNF-α tumor necrosis factor-α TNF-α tumor necrosis factor-α 1 Introduction Hydrocephalus is a common medical condition characterized by abnormalities in the secretion, circulation and...
Serum exosomal miR-200c is a potential diagnostic biomarker for breast cancer
Abstract Background Breast cancer (BC) is one of the most common malignancies in women. Exosomes are widely found in body fluids and carry microRNAs (miRNAs) that reflect the biological properties of the parental cells. Our study aimed to investigate the differential expression of miR-200c in BC serum exosomes and its diagnostic value.
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