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Huiying Fang on Muck Rack

Huiying Fang

As seen in: Nature, Aging
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Articles

Macrophage ALDH2 drives immunotherapy resistance by silencing CXCL9 through metabolic-epigenetic crosstalk

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By Huiying Fang, Jiazheng Sun, Qian Xiao, He Ren, Yuru Chen, Jiazhou Liu, Daqiang Song, Tiantian Chen, Linling Wu, Pin Wang, Jian Yue, Xiaoyu Wang, Qilin Yang, Yuxian Wei, Huimin Du, Weiyan Peng, Zhu Qiu, Li Zhang, Jingyuan Wan, tong liu, Guosheng Ren, Hongzhong Li
| Nature Verified
Abstract The metabolic basis of tumor-associated macrophages (TAMs)-driven immune checkpoint blockade (ICB) resistance remains poorly understood. Here, in patients with immunotherapy-resistant cancer, we identify significant enrichment of TAMs marked by elevated aldehyde dehydrogenase 2 (ALDH2) expression.
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Causal role of blood metabolites in HER-positive and HER-negative breast cancer: a Mendelian randomization (MR) study

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By Jian Yue, Sheng Chen, Lei Gu, Huiying Fang
| Aging Verified
Research Paper Volume 16, Issue 15 pp 11626—11655 1 Chongqing Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China 2 Department of Breast and Thyroid Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China 3 Department of Breast Surgery, Gaozhou People’s Hospital, Gaozhou, China 4 Department of Breast Cancer Center, Chongqing Key Laboratory for Intelligent Oncology in Breast...
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