Isabelle Richard on Muck Rack

Isabelle Richard

France
As seen in: EHESP - École des hautes études en santé publique, Color Research & Application, Le Monde, MDPI, La Croix, The Lancet, Take 5, Eurozine
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Articles

Inhibiting EZH2 Alleviates Osteoarthritis and Pain in an Experimental Murine Model Through Modulating Synovial and Macrophage Inflammation, Axon Guidance, and Osteoclastogenesis

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By Mahdia Taïeb, Isabelle Richard, Sybille Brochard, Alison Vanlaeys
| biorxiv.org
Abstract Enhancer of zeste homolog 2 (EZH2), a histone methyltransferase, has gained attention as a promising therapeutic target in osteoarthritis (OA) due to its central role in modulating inflammation, catabolism, and hypertrophy within chondrocytes. Previous studies have further demonstrated that EZH2 inhibition can slow OA progression in surgically induced mouse models, highlighting its potential in reducing joint degradation.
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In Silico Structural Prediction for the Generation of Novel Performant Midi-Dystrophins Based on Intein-Mediated Dual AAV Approach

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By Laura Palmieri, Maxime Ferrand, Isabelle Richard, Sonia Albini
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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In Silico Structural Prediction for the Generation of Novel Performant Midi-Dystrophins Based on Intein-Mediated Dual AAV Approach

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By Laura Palmieri, Isabelle Richard, Sonia Albini, Maxime Ferrand
| preprints.org
Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 4 September 2024 / Approved: 5 September 2024 / Online: 5 September 2024 (08:20:45 CEST) Palmieri, L.; Ferrand, M.; Vu Hong, A.; Richard, I.; Albini, S. In Silico Structural Prediction for the Generation of Novel Performant Midi-Dystrophins Based on Intein-Mediated Dual AAV Approach. Preprints 2024, 2024090395.
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