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JAMES GULLEY

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Articles

GPR15-guided CD8 + T regulatory cells control intestinal inflammation

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By Jing Cui, Zuojia Chen, Jia Nie, maria zhu, CHEN Xiang, Samuel D. Chauvin, Wiem Lassoued, Can Liu, Kartika Padhan, Jian Song, Joy A. Pai, Borja Ocón, Yifan Yang, Yikun Yao, Ann Park, Justin Q. Gabrielski, Lixin Zheng, Ping Du Jiang, Yu Zhang, Huie Jing, Leilei Xu, Vicky Chen, Brent A. Calabresi, Stefania Pittaluga, David E Kleiner, Clifton L. Dalgard, Sinan Sari, Salim Can, Elif Karakoc-Aydiner, Safa Baris, Baran Erman, Jocelyn A. Silvester, Gwen Saccocia, Eman K. Buhamrah, Khaled H. Husain, Zahra Chavoshzadeh, Nima Rezaei, Ali İşlek, Hasan Baş, Fatma Dereli Devrez, Rafah Mackeh, Ivan Fuss, Daniel S. Reich, Shania Bailey, Houssein Abdul Sater, JAMES GULLEY, Juraj Kabat, Margery G. Smelkinson, Sundar Ganesan, Zhenghao Chen, Peter C Grayson, Neelam Redekar, Justin B Lack, Zhiyong Lu, Bernice Lo, Hassan Abolhassani, Ahmet Ozen, Athos Bousvaros, Scott B. Snapper, Eugene C Butcher, Juan C. Ravell, Remy Bosselut, Helen Su, Chuan Wu, Michael J. Lenardo
| Nature Verified
Abstract Inflammatory bowel disease (IBD) causes chronic suffering from gastrointestinal inflammation and dysfunction that can progress to colon cancer1,2. The disease prevalence is increasing and there is an urgent need to better understand its pathogenic mechanisms to improve treatment.
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HyperHealth: a pilot study on AI-driven COVID-19 detection using hyperspectral fingertip images

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By Emanuela Marasco, Maheen Khan, John Deeken, Raghavendra Ramachandra, Fatima H Karzai, M. Morelli, Charalampos S Floudas, JAMES GULLEY, Shruti Wagle, Mason Rule, Katherine Lee-Wisdom
| Nature Verified
Abstract Despite the reduced impact of COVID-19 due to widespread vaccination and improved treatments, a critical need remains for accessible, scalable, and rapid screening tools to address current and future infectious disease threats. Hyperspectral Imaging (HSI) may be such a tool, but the current limited availability of data from COVID-19 positive individuals hinders traditional supervised learning approaches.
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Docetaxel enhances Vβ-directed T-cell activation and antitumor immunity mediated by a bifunctional TCR agonist in breast and prostate cancer models

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By Kellsye P Fabian, Ginette S. Santiago-Sánchez, Francesca Rosato, Michelle R Padget, Zhen Su, Jacques Moisan, Madan Katragadda, Jeffrey Schlom, JAMES GULLEY, Andrew Bayliffe, James Hodge, Jonelle K. Lee, Cailyn Lee
| Frontiers in Immunology
Abstract Background: STAR0602 is a selective bifunctional T cell agonist targeting Vβ6/Vβ10 T-cell receptors fused to interleukin-2, with emerging clinical activity in anti-PDL1–resistant tumors. Its murine surrogate, mSTAR1302, expands Vβ13 T cells and mediates antitumor activity. Docetaxel, beyond its cytotoxic effects, induces immunogenic modulation of tumor cells.
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