Skip To Main Content
Jiaying Shen on Muck Rack

Jiaying Shen

As seen in: Nature, Wiley Online Library, MDPI, ACS Publications, Science Magazine, Royal Society of Chemistry, Optica
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Jiaying

Contact Jiaying, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Natural killer cell-mediated immunosurveillance modulates liver cancer evolution through cancer stemness enhancement and lipid metabolism reprogramming

|
By Boqiang Liu, Ruya Sun, Jing He, Hao Shen, Weiqi Li, Yi Wang, Weijun Zhao, Chenqi Jin, Yuanshi Tian, Lingfeng Ma, Lidan Hou, MingYu Chen, Jiaying Shen, Bo Shen, Xiao Liang, Hong Yu, Yifan Wang Verified, Di Wang, Xiujun Cai, Binghan Jin
| Nature Verified
Abstract Tumor evolution enables liver cancer cells to acquire survival advantages and evade therapy-induced cell death. However, the role of natural killer (NK) cells in liver cancer evolution remains unclear. Here, we establish immune-humanized spatiotemporal liver cancer models and integrate single-cell, spatial transcriptomic, and CRISPR/Cas9 screening analyses to investigate this process.
Open in Who Shared Issue with article?

Targeting WIP1 reprograms immunosuppressive tumor microenvironment to potentiate immunotherapy response in colorectal cancer

|
By Lini Chen, Shijin Yuan, Yanmei Wang, Hanying Wang, Liyuan Zhu, Chandra Wijaya, Jiaying Shen, Dingwei Chen, Pingting Ying, Chaoqun Wang, Chentao Li, Xian Wang, Lifeng Feng, Hongchuan Jin, Miaoqin Chen, Jinye Xu
| Nature Verified
Abstract While immunotherapy based on immune checkpoint inhibitors (ICIs) shows limited efficacy in colorectal cancer (CRC) due to its immunosuppressive tumor microenvironment, strategies to activate innate immunity remain underexplored. Here, we identified wild-type p53-induced phosphatase 1 (WIP1/PPM1D) as a critical immunosuppressive driver in CRC, with its expression significantly upregulated in tumor tissues.
Open in Who Shared Issue with article?

Robust room-temperature ferroelectricity in the wide-bandgap semiconductor Ga2O3

|
By Jiaying Shen, Weng Fu Io, Chang Liu
| Science Magazine Verified
Abstract For decades, the integration of power handling and nonvolatile memory has been fundamentally impeded by the incompatibility between wide-bandgap semiconductors and ferroelectric materials. We resolve this challenge by demonstrating robust room-temperature ferroelectricity in epitaxial metastable κ-Ga2O3, grown via industry-compatible metal-organic chemical vapor deposition, creating an intrinsically ferroelectric wide-bandgap semiconductor.
Open in Who Shared Issue with article?
See all 16 articles