Jie Yin
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Mefatinib versus gefitinib as a first-line treatment for EGFR-mutated non-small cell lung cancer: a randomized, double-blind, multicenter phase III study
Abstract Mefatinib, a novel second-generation epidermal growth factor (EGFR) tyrosine kinase inhibitor that has shown promising antitumor activity in targeting non-small cell lung cancer (NSCLC) with common and uncommon EGFR-activating mutations.
A molecular glue induces aberrant STING oligomerization and inhibits autoinflammatory diseases
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Abstract Dysregulated activation of the stimulator of interferon genes (STING) pathway underlies various inflammatory and autoimmune pathologies. Since STING oligomerization is fundamental to its biological function, targeted modulation of this polymerization process presents a promising therapeutic approach. However, achieving precise control over STING polymerization has remained a significant challenge.
By Zi-Wen Feng, Ting Zeng, Qing Shu, Hai-Guo Yu, Wei Dai, Xue-Chun Liu, Feng Xu, Hui Li, Shi-Duo Zhang, Lin-lin Li, Nan-Nan Chen, Xiao-Yan Liu, Zi-Wen Liu, Jie Yin, Mei-Rong Alice Chen, Dan-Dan Wang, Xiao-Li Xu, Xiao-Zhong Li, Xin-Jian Tian, Ye-Ling Zhou, Hong-Tao Shen, Chun-Chen Che, Ling-Yun Sun, Yi-Bei Xiao, Qi-Dong You
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Nature
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Synergistic impacts of climate and land use/land cover changes on the spatiotemporal evolution of landslides in Kerala
?Mathematical formulae have been encoded as MathML and are displayed in this HTML version using MathJax in order to improve their display. Uncheck the box to turn MathJax off. This feature requires Javascript. Click on a formula to zoom. Abstract Climate change and land use/land cover (LULC) transitions are increasingly influencing landslide dynamics in mountainous regions, yet their combined effects remain insufficiently quantified.
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