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Jieyin Li

As seen in: Cell Reports Medicine
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Articles

Plasma growth-associated protein 43 correlates with synaptic loss in Alzheimer’s disease

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By Guoyu Lan, Binyin Li, Mengjie Wang, Aatmika Barve, Morvane Colin, Luc Buée, Laihong Zhang, Mingxing Jiang, Jie Yang, Anqi Li, Zhengbo He, Xin Zhou, Yalin Zhu, Yue Cai, Pan Sun, Lin Liu, Linting Chen, Lili Fang, Yiying Wang, Mingxu Li, Xuhui Chen, Dai Shi, Chenghui Ye, Xiang Fan, Qingyong Wang, Liemin Zhou, Zhen Liu, Ying Han, Lu Wang, Guanxun Cheng, Yihui Guan, Ruiqing Ni, Kevin Richetin, Fang Xie, Tengfei Guo, Jieyin Li
| Cell Reports Medicine Verified
Keywords synaptic loss blood biomarkers GAP-43 extracellular vesicles neuropathology Alzheimer’s disease Introduction Dementia is the leading cause of disability and death among older adults and currently affects over 55 million people worldwide.1 Approximately 60%–70% of dementia cases are attributed to Alzheimer’s disease (AD), marked by the deposition of extracellular amyloid-β (Aβ) plaques and intraneuronal tau tangles composed of phosphorylated tau (p-tau), and then dementia with Lewy...
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