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Articles by John Burn
Salcombe Yacht Club Autumn Series Race 4 - a light Force 2 southerly light breeze Original
Salcombe Yacht Club Autumn Series Race 4 - a light Force 2 southerly light breeze by David Greening & John Burn 27 Sep 16:00 BST Solo Race (by David Greening) Held just after a low water spring tide in a light Force 2 southerly light breeze, the Solo fleet assembled at the East Portlemouth end of the starting line, under the watchful eye of Race Officer Andy Savell.
Salcombe Yacht Club Autumn Series Race 3 - High winds and rain Original
Salcombe Yacht Club Autumn Series Race 3 - High winds and rain by John Burn & David Greening 23 Sep 18:03 BST Fast Handicap Fleet An afternoon of high winds and rain didn't stop four hardy teams from taking to the water on Saturday for the third instalment of the Autumn Series. Fran Gifford and Frankie Burn in the Merlin opted to return to Batson, but not before enjoying a few blasts across the Estuary as the powerful gusts funnelled down the harbour.
Salcombe Yacht Club Autumn Series Race 2 - Fast Handicap and Solo fleet reports Original
Salcombe Yacht Club Autumn Series Race 2 - Fast Handicap and Solo fleet reports by John Burn & David Greening 14 Sep 12:18 BST Fast Handicap Fleet Report (by John Burn) There was definitely a change in the weather. Summer has fast departed, with a notable chill in the air, but thankfully the water is still warm and, when the sun appears, it remains pleasant enough. Eight boats intended to make the start for the second race of the Autumn Series, but only seven appeared on the line.
Helly Hansen Merlin Rocket Week 2026 at Salcombe Yacht Club - Overall Original
Helly Hansen Merlin Rocket Week 2026 at Salcombe Yacht Club - Overall by John Burn 11 Jul 18:56 BST A.M Race Jason Andrews and Tim Fells made the most of a bold port-tack flyer at the start, reaching Crossways first with a modest early lead. From there, they headed straight towards Ditch End, while the majority of the fleet pushed further out towards Snapes before gybing back to join the Ditch End contingent.
Helly Hansen Merlin Rocket Week 2026 at Salcombe Yacht Club - Day 5 Original
Helly Hansen Merlin Rocket Week 2026 at Salcombe Yacht Club - Day 5 by John Burn 10 Jul 09:29 BST Day 5 AM — Green v Black Another sunny, warm morning greeted the fleet for Day 5 of the 2026 Helly Hansen Merlin Rocket Week, although the breeze was doing its best to stay on holiday. There was just enough wind to get the boats away cleanly, with the Race Officer setting a compact course around the main harbour.
Aspirin for cancer prevention in individuals with Lynch syndrome: first results from the CaPP3 multicentre, randomised, double-blind, non-inferiority trial
Introduction In 1988, Kune and colleagues1 noted that people taking aspirin-containing medications were under-represented among those presenting with colorectal cancer. In 1995, Giovannucci and colleagues2 reported on aspirin use in 89 446 US female health professionals and concluded that: “Regular aspirin use, at doses similar to those recommended for the prevention of cardiovascular disease, substantially reduces the risk of colorectal cancer.
Helly Hansen Merlin Rocket Week 2026 at Salcombe Yacht Club - Days 3 & 4 Original
Helly Hansen Merlin Rocket Week 2026 at Salcombe Yacht Club - Days 3 & 4 by John Burn 8 Jul 17:26 BST Day 3 Morning Race - Green v Blue A light and fickle breeze made for a hugely unpredictable morning race, with the fleet splitting early between the Town and Portlemouth shores. 3820 and 3812 initially broke clear up the Town Shore, chased by 3746, while 3738 led the Portlemouth group with 3611 and 3803 close behind.
Mol005 LYNCH SYNDROME NETWORK CONSENSUS (LYNSYNC). INTERNATIONAL GUIDELINES ON CLINICAL MANAGEMENT, SURVEILLANCE, AND PREVENTION
On Behalf Of The LYNSYNC Group
Salcombe Yacht Club Sailing Club Series Race 1 Original
Salcombe Yacht Club Sailing Club Series Race 1 by John Burn, Allan Willcox & David Greening 27 Apr 08:52 BST Yawl Race (by John Burn) Saturday the 25th marked the start of the Salcombe Yacht Club Sailing Club Series, and what better conditions for the 18-strong Yawl fleet than a Force 3 easterly, high tide, and wall-to-wall sunshine.
Salcombe Yacht Club Spring Series Race 4 Original
Salcombe Yacht Club Spring Series Race 4 by John Burn 2 Apr 12:34 BST Course: 7-3-7-2 It was an early start for the Fast Handicap fleet on Saturday, with racing brought forward to 10am thanks to ongoing dredging work in the Harbour—nothing like a bit of industrial encouragement to get sailors out of bed. Sunshine and a solid north-westerly greeted the competitors, making a clean getaway from the start line essential, especially with the harbour delivering its usual wind lottery.
Salcombe Yacht Club Spring Series Race 3 Original
Salcombe Yacht Club Spring Series Race 3 by Steve Walter, John Burn & Graham Cranford-Smith 23 Mar 11:57 GMT Short-Race Handicap Race (by Steve Walter) Four ILCA 6's were out on Saturday enjoying the spring weather.
Salcombe Yacht Club Spring Series Race 1 Original
Salcombe Yacht Club Spring Series Race 1 by John Burn & David Greening 8 Mar 15:12 GMT Fast Handicap Fleet by John Burn A dull grey day, with a 5-10 knot ENE breeze and a spring low tide, probably had a lot to do with the low turnout in the Fast Handicap for the first race of the Spring Series. Race Officer Fran Gifford wisely avoided The Bag and set a course in the main harbour.
Salcomber Yacht Club 2026 Commissioning Race Original
Salcomber Yacht Club 2026 Commissioning Race by John Burn 2 Mar 05:25 GMT Here we go again... After a slightly shorter than usual winter break, Batson Boat Park was once again a hive of activity as 19 boats rigged up and launched into a blissfully empty harbour. For once, the rain gave everyone a day off and allowed the sun to do its thing.
Festive Series 2025 at Salcombe Yacht Club Original
Festive Series 2025 at Salcombe Yacht Club by John Burn 2 Jan 19:41 GMT The 2025 Festive Series once again provided exciting handicap racing at Salcombe. Along with the commissioning race, it is now the only time all the different dinghy sections of the club get to race against each other. As always, the weather played its part and, of the four scheduled races, three were able to go ahead.
Understanding How Aspirin Prevents Metastasis | NEJM
Are you a member of an institution such as a university or hospital?Learn more about Institutional Access Notes This article was updated on December 11, 2025, at NEJM.org. Disclosure forms provided by the authors are available with the full text of this article at NEJM.org. Supplementary Material Disclosure Forms (nejmcibr2502386_disclosures.pdf)
Salcombe Yacht Club Three Creeks Challenge Original
Salcombe Yacht Club Three Creeks Challenge by John Burn 18 Aug 17:49 BST SYC has put on a lot of sailing so far this season, and after two busy weeks of regattas, if you thought there would be a forced rest day on Saturday, you were mistaken. Numbers were down across all fleets—perhaps the 40-knot nor'easter being recorded at Prawle Point was deterrent enough for most, or maybe it was just tired bodies and legs? Who knows.
Suspending the NHS medicines repurposing programme in England is a missed opportunity
Ruth E Langley, oncologist1, Gemma Vilahur, cardiovascular researcher23, Mairead Mackenzie, patient representative4, John Burn, geneticist5 1MRC Clinical Trials Unit, University College London, UK 2Research Institute Sant Pau (IR SANT PAU), Barcelona, Spain 3Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares, (CIBER CV) Madrid, Spain 4Trustee, Independent Cancer Patient Voices, UK 5Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne,...
Salcombe YC Sailing Club Series Final Race Original
Salcombe YC Sailing Club Series Final Race by David Greening & John Burn 9 Jun 19:29 BST Solo fleet race With winds forecast in excess of 30mph all week, ten hardy Solo sailors made it to the Salcombe Yacht Club starting area, and despite the conditions seeming sailable most chose to wait until the preparatory signal by using the comparative protection of Smalls Cove. The Race Officer Kevin Anderson set a course of 17232 on a shifty Force 7 south westerly and a flood tide.
Stones Boatyard Salcombe Yawl and ILCA open meeting at Salcombe Yacht Club
Stones Boatyard Salcombe Yawl and ILCA open meeting at Salcombe Yacht Club by John Burn & Lucy Burn 2 Jun 04:57 PDT Yawl fleet report The late May Bank Holiday once again saw the iconic Salcombe Yawls take to the water for the Stones Boatyard Yawl Open Meeting—a fixture now synonymous with top-class racing, fierce competition, and of course, the legendary Yeti prizes that Stones generously provide. And this years event? Possibly the best yet.
Salcombe Yacht Club Spring Series - Race 5 Original
Salcombe Yacht Club Spring Series - Race 5 by John Burn & David Greening 14 Apr 10:14 BST Fast Handicap fleet (by John Burn) Saturday's race saw a mass turnout, with 20 Yawls taking to the water for the final race of the Spring Series. The Yawls had spent the morning in a training session and were keen to put their newly honed skills into practice.
Salcombe Yacht Club Spring Series - Race 2 Original
Salcombe Yacht Club Spring Series - Race 2 by John Burn & David Greening 17 Mar 17:35 GMT Handicap fleet report A brisk 10-15 knot north-easterly, paired with plenty of blue sky and sunshine, set the stage for Race 2 of the Spring Series. Launching once again at low tide turned into a muddy affair, but it was made more bearable thanks to Malcolm Mackley, who was efficiently whisking trollies away. The Fast Handicap was again a two-boat contest.
By cutting costs Jim Ratcliffe is addressing the wrong problem
Sir Jim Ratcliffe knows how to turn around a struggling industrial business. The British billionaire, now in charge of sporting operations at footballing giant Manchester United, made his name and fortune buying and rejuvenating underperforming chemical businesses over more than two decades. But does he know how to turn around a struggling football club? The evidence increasingly suggests not.
Salcombe Yacht Club Summer Series - Race 6
Salcombe Yacht Club Summer Series - Race 6 by John Burn 29 Jul 09:31 PDT A superyacht, a broken mast, and a committee boat start — race 6 of the summer series certainly provided plenty of excitement for both spectators and competitors. Course 1-7-1-3-2 Five red fleet and six blue fleet arrived at the start line, which had been located just off Mill Bay. Pin End was the place to be, and with most of the fleet picking up on this, getting away cleanly was going to be tricky.
Constitutional mismatch repair deficiency mimicking Lynch syndrome is associated with hypomorphic mismatch repair gene variants - npj Precision Oncology
Abstract Lynch syndrome (LS) and constitutional mismatch repair deficiency (CMMRD) are distinct cancer syndromes caused, respectively, by mono- and bi-allelic germline mismatch repair (MMR) variants. LS predisposes to mainly gastrointestinal and genitourinary cancers in adulthood. CMMRD predisposes to brain, haematological, and LS-spectrum cancers from childhood.
Salcombe Yacht Club Sailing Club Series - Race 4
Salcombe Yacht Club Sailing Club Series - Race 4 by John Burn & David Greening 13 May 03:10 PDT Solo fleet The forecast Easterly breeze did not put off fifteen Solo sailors from coming to the starting line. Fortunately, the wind inside of the harbour was aligned to allow beat and running, and race officer Graham Cranford-Smith set an adventurous course that took the fleet out of the harbour at low tide and taking advantage of the stronger Easterly breezes to be found beyond Lambury Point.
Salcombe Yacht Club Sailing Club Series - Race 1 Original
Salcombe Yacht Club Sailing Club Series - Race 1 by John Burn & David Greening 22 Apr 14:34 BST Fast Handicap Report (by John Burn) The commencement of the annual Yawl training weekend marked the kick-off for the Sailing Club Series, boasting a formidable lineup of 20 boats at the starting line.
Salcombe Yacht Club Spring Series Race 6 Original
Salcombe Yacht Club Spring Series Race 6 by John Burn & David Greening 15 Apr 10:39 BST Handicap Report (by John Burn) Ideal weather conditions attracted a strong turnout for the concluding race of the spring series, with 8 teams assembling at the start line.
Salcombe Yacht Club Spring Series Race 4 Original
Salcombe Yacht Club Spring Series Race 4 by John Burn & David Greening 2 Apr 10:09 BST Handicap Report (by John Burn) Under the radiant Easter weekend sun and a brisk 10-15 knot SSE breeze, a bustling fleet of nine boats gathered for race 4 of the spring series. Race Officer Simon Yates set a course consisting of 1-7-5-7-1-3, capitalising on the favourable conditions at the top end of The Bag.
Salcombe Yacht Club Spring Series Race 3
Salcombe Yacht Club Spring Series Race 3 by David Greening & John Burn 25 Mar 09:41 PDT Solo Spring Series Race 3 (by David Greening) With the cognoscente informing themselves with weather apps indicating gusts in excess of thirty five knots from the North West and therefore saving themselves a wasted journey, a reduced fleet of nine Solos headed to the starting area on the basis that if they could survive the run from the slipway to the start line, then the hills to the west of the Ria would...
Why the phrase "We in the West" is simply a prelude to an avalanche of lies
By John Burn “WE in the West.” What a seductive phrase. It slides its arm around your shoulder and invites you to believe that the speaker is on your side. But ask yourself this: by what measure am I part of any ‘we’ that includes the Whitehouse and the Pentagon, Lockheed and BAE Systems? In what way, are their interests my interests? What evidence do I have to suppose that the Whitehouse and the Pentagon or the Heads of the Armed Service here in Britain are remotely interested in anything I think?
Salcombe Yacht Club Winter Series Race 2 Original
Salcombe Yacht Club Winter Series Race 2 by John Burn & David Greening 13 Nov 21:33 GMT Handicap Report A mixture of seven boats took to the water on Saturday, despite the total lack of any discernible wind. Race Officer Geof Gilson set a course that would keep the fleet in front of the race box, ensuring he had the opportunity, if he so wished to end the suffering should the conditions not improve.
Transforming the care of people with Lynch syndrome: a system-wide approach
In this issue, Monahan et al1 describe progress in addressing the lack of diagnosis of Lynch syndrome in the English National Health Service with a bold attempt to fix a leaking pathway. Lynch syndrome (LS) describes a cluster of overlapping phenotypes resulting from a germline loss of function in an allele at four loci responsible for mismatch repair (MMR) proteins.
Yawls, 505, RS400, and Albacore Compete in Salcombe Yacht Club Autumn Series Race 7
Key points: Thirteen teams participated in the Salcombe Yacht Club Autumn Series Race 7, including Yawls, a 505, RS400, and Albacore. The race took place in Salcombe with a north-westerly wind, making navigation in front of the clubhouse a challenge. Olly Turner and Chris Skelhorn in Y68 claimed the first-place finish in the Fast Handicap Race, while Tim Law won the Solo Race. The Salcombe Yacht Club Autumn Series Race 7 took place on a sunny but chilly day.
Salcombe Yacht Club Autumn Series Race 7
Salcombe Yacht Club Autumn Series Race 7 by John Burn & David Greening 17 Oct 01:16 PDT Fast Handicap Report (by John Burn) Once again, on Saturday, the sun was shining down on Salcombe, but there was a notable chill in the air for the penultimate race in the Autumn Series. 13 teams arrived at the start: 9 Yawls, a 505, RS400, Albacore, and it was good to see Mark Savage out in his K1 again.
Salcombe Yacht Club Autumn Series Race 6 Original
Salcombe Yacht Club Autumn Series Race 6 by John Burn & David Greening 9 Oct 05:38 BST Fast Handicap Report (by John Burn) The exceptional October weather set the perfect backdrop for the sixth race of the Fast Handicap Autumn series. A mixture of eight teams arrived at the start to tackle the course 1-7-1-3 set by expert race team Graham and Fiona Cranford Smith.
Salcombe Yacht Club Autumn Series Race 5
Salcombe Yacht Club Autumn Series Race 5 by John Burn & David Greening 2 Oct 02:19 PDT Handicap Fleet (by John Burn) A very low spring tide coinciding with the race start left few options available to Race Officer John Burn on Saturday. Mark 7 and Mark 5, though probably not completely dry, wouldn't allow much rounding room.
Transforming the care of people with Lynch syndrome: a system-wide approach
Bowel cancer Cancer screening Colorectal cancer Endometrial cancer Nursing In this issue, Monahan et al1 describe progress in addressing the lack of diagnosis of Lynch syndrome in the English National Health Service with a bold attempt to fix a leaking pathway. Lynch syndrome (LS) describes a cluster of overlapping phenotypes resulting from a germline loss of function in an allele at four loci responsible for mismatch repair (MMR) proteins.
Paul and Julie Rayson Shine in Red Fleet
Key points: The Hassall Law Salcombe Yawl Open saw 19 red fleet Yawls competing in challenging sailing conditions Notable performances included Paul and Julie Rayson taking first position in Race 1 Olly Turner and Chris Skelhorn emerged as the overall winners of the event in the Blue Fleet The Hassall Law Salcombe Yawl Open took place at Salcombe Yacht Club over the weekend, with a strong turnout of red fleet Yawls.
Hassall Law Salcombe Yawl Open at Salcombe Yacht Club Original
Hassall Law Salcombe Yawl Open at Salcombe Yacht Club by John Burn & Robert Smith 28 Sep 06:26 BST Red Fleet Report (by John Burn, Y170) A bumper turnout for the September Open Meeting saw 19 red fleet Yawls take to the water. What makes this even more impressive is that there were a few notable absent teams who, for their own reasons, were unable to attend. The honour of PRO was bestowed upon our vice commodore, Tim Fells, who had the unfavourable task of 10 starts to deal with on Saturday alone.
John and Frankie Burn and Tim Fells Achieve Victory in Salcombe Yacht Club Autumn Series Race 2
By John Burn & David Greening via sail-world.com, Key points: Race 2 of the Salcombe Yacht Club Autumn Series took place with a fleet of Yawls and an Albacore competing John and Frankie Burn emerged as the winners in the Yawls category Tim Fells secured victory in the Solo race The Salcombe Yacht Club Autumn Series Race 2 took place with competitive races in the Fast Handicap and Solo classes.
Salcombe Yacht Club Autumn Series Race 2
Salcombe Yacht Club Autumn Series Race 2 by John Burn & David Greening 11 Sep 10:45 BST Fast Handicap (by John Burn) Y Course - 6 - 2 Seven Yawls and one Albacore turned out on Saturday, and under the expert eye of Race Officer Will Henderson, they got underway, heading off towards Mark Y. While most of the fleet preferred Ditch End, Greg and Claire Hoar in Y145, along with Andrew and Sheila Squire in the Albacore, headed off towards Snapes before making their dash into Yalton Creek.
Hendersons Dominate Yawls Race and Paul Ellis Takes Victory in Solos at Salcombe Yacht Club Autumn Series Race 1
By John Burn & David Greening via sail-world.com, Key points: Salcombe Yacht Club Autumn Series Race 1 provides exciting racing action for Yawls and Solos The Hendersons dominate the Yawls race, securing a comfortable win Nine Solos compete in a challenging race with Paul Ellis taking the victory The Salcombe Yacht Club held the first race of its Autumn Series, with twelve Yawls taking part in the Fast Handicap category.
Salcombe Yacht Club Autumn Series Race 1 Original
Salcombe Yacht Club Autumn Series Race 1 by John Burn & David Greening 5 Sep 09:47 BST Fast Handicap (by John Burn) Course 3-1-3-1-3-1 Twelve boats arrived at the start line, made up solely of Yawls. They were greeted by wall-to-wall sunshine, a NE 8 knot breeze, and a slack tide in the very last stages of its cycle. Will and Mandy Henderson in Y168 took control, reaching Crossways first, with Olly Turner and Chris Skelhorn in Y68 in close quarters.
Salcombe Yacht Club Three Creeks Challenge Original
Salcombe Yacht Club Three Creeks Challenge by John Burn 16 Aug 11:12 BST The much-anticipated annual Three Creeks Challenge unfolded on Saturday. Contestants, after completing the initial windward mark designated by the Race Officer, embraced the freedom to chart their own course through the Estuary. Given conditions, the quartet participating in the slow handicap category were directed to Mark 2 instead of Mark 1, setting the stage for their journey towards Saltsone or Yalton.
Will and Mandy Henderson win Salcombe Yacht Club Summer Series race 7
By John Burn & David Greening via sail-world.com, Key points: Salcombe Yacht Club Summer Series race 7 took place after bad weather caused the cancellation of races 5 and 6. Sailors enjoyed ideal sailing conditions with wind from the south-west, a neap flood tide, and sunny weather. The Yawl fleet saw Will and Mandy Henderson in Y168 take the lead early on and hold off John Burn and Tristan Stone in Y170 to win the race.
Salcombe Yacht Club Summer Series - Race 7 Original
Salcombe Yacht Club Summer Series - Race 7 by John Burn & David Greening 31 Jul 19:43 BST After losing races 5 and 6 due to bad weather, it was great to be back out on the water Saturday afternoon for the last race of the Summer Series. Sailors and spectators alike were treated to a perfect combination of wind from the south-west, a neap flood tide (in the latter stages), and glorious sunshine. What more could you want? How about a blast up to Gerston and Back?
This Week's Salcombe Yacht Club Sailing Report
Read this week's sailing report from Salcombe Yacht Club. YAWL FLEET ~By John Burn Lots of wind, lots of tide, and a constant stream of shifty gusts resulted in only six Yawls hitting the water on Saturday. Unfortunately, two of them, for their own reasons, headed home before the start, leaving just four to battle it out with each other in the feisty conditions. credit Lucy Burn As the start hooter sounded, a monster gust powered down the estuary.
Salcombe YC Summer Series Race 4
By BVMSports Team By John Burn, David Greening & Andrew Groves via sail-world.com, Salcombe Yacht Club Summer Series Race 4 by John Burn, David Greening & Andrew Groves 3 Jul 09:14 PDT 25 June 2023 Yawl Fleet (by John Burn) Lots of wind, lots of tide, and a constant stream of shifty gusts resulted in only six Yawls hitting the water on Saturday. Unfortunately, two of them, for their own reasons, headed home... Read more on Publisher's website
Salcombe Yacht Club Summer Series Race 4 Original
Salcombe Yacht Club Summer Series Race 4 by John Burn, David Greening & Andrew Groves 3 Jul 17:14 BST Yawl Fleet (by John Burn) Lots of wind, lots of tide, and a constant stream of shifty gusts resulted in only six Yawls hitting the water on Saturday. Unfortunately, two of them, for their own reasons, headed home before the start, leaving just four to battle it out with each other in the feisty conditions.
Salcombe YC Summer Series Race 3
By BVMSports Team By John Burn & David Greening via sail-world.com, Salcombe Yacht Club Summer Series Race 3 by John Burn & David Greening 26 Jun 03:52 PDT 24 June 2023 Fast Handicap (by John Burn) Course M,3, 1, 3, 2 There were just three entrants for race 3 of the Summer Series: Mark Waterhouse and Fran Gifford in a Merlin Rocket, John and Annie McLaren in an RS400, and Mark... Read more on Publisher's website
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