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Jonathan Yao on Muck Rack

Jonathan Yao

As seen in: Nature, Food & Wine, BioRxiv, MDEdge, The Berkeley Beacon, Warwick Beacon, Food & Wine en Español
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Articles

Asymmetric histone inheritance regulates olfactory stem cell fates during regeneration

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By Binbin Ma, Guanghui Yang, Jonathan Yao, Charles Chong-han Wu, Jean Vega, Gabriel L. Manske, Saher Sue Hammoud, Satrajit Sinha, Abhyudai Singh, Haiqing Zhao, Xin McRae Chen
| Nature Verified
Abstract The olfactory epithelium possesses an adult stem cell population, the horizontal basal cells (HBCs), to permit lifelong tissue regeneration. Here, we show that HBCs exhibit asymmetric inheritance of histone H4 but not H2A-H2B during olfactory epithelium regeneration in mice.
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Asymmetric Histone Inheritance Regulates Differential Transcription Re-initiation and Cell Fate Decisions in Mouse Olfactory Horizontal Basal Cells

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By Binbin Ma, Guanghui Yang, Jonathan Yao, Charles C. Wu
| BioRxiv
Abstract To understand epigenetic inheritance in mammals, we investigate cell division modes and histone inheritance patterns in the mouse olfactory epithelium using an injury-induced regeneration model. Horizontal basal cells (HBCs), the adult stem cells in this tissue, undergo asymmetric division, coinciding with asymmetric histone H4 inheritance in vivo. Primary HBCs recapitulate both asymmetric cell division and asymmetric histone inheritance for H4, H3, and H3.3, but not H2A-H2B.
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Ginger-Scallion Oil Recipe

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By Jonathan Yao
| Food & Wine Verified
The electric-green ginger-and-scallion oil from Best New Chef Jonathan Yao improves everything it touches, from salad dressings to cold noodles. At Kato in Los Angeles, Yao drizzles the oil over Steamed Fish with Soy Broth.
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