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Joycelyn Tan

As seen in: MSN Singapore, MSN Malaysia, Nature, BioRxiv, Cell Metabolism, Stem Cell Reports, Vulcan Post, BEAMSTART, Discover KL
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Articles

Publisher Correction: Polyamine-dependent metabolic shielding regulates alternative splicing - Nature

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By Amaia Zabala-Letona, Maria Ponce-Rodriguez, Saioa Garcia-Longarte, Isabel Mendizabal, Malgorzata Ewa Rogalska, Joycelyn Tan, Pilar Ximenez-Embun, Maciej Zakrzewski, Ianire Astobiza, Sarah Cherkaoui, Maria Sendino, Amaia Ercilla, Laura Bozal-Basterra, Encarnación Pérez-Andrés, Juan A. Ferrer-Bonsoms, Maciej Cieśla, Joan Seoane, Rosa Barrio, James Sutherland Verified, Ana M. Aransay, Juan Manuel Falcon-Pérez, Barbara Martinez-Pastor, Francisco Blanco, Michael D. Hogarty, Raphael J. Morscher, Remigiusz A. Serwa, Jesús Jiménez-Barbero, Gonzalo Jiménez-Osés, Alejo Efeyan, Lydia W. S. Finley, Javier Muñoz, Juan Valcárcel
| Nature Verified
Correction to: Nature https://doi.org/10.1038/s41586-025-09965-1 Published online 14 January 2026 In the version of the article initially published, in Fig. 1g, the three right-hand labels reading “24 h” should have read “SAT1”, “SMARCA1” and “ACTB”. This correction has been made to the HTML and PDF versions of the article, as seen in Fig. 1, below. Fig. 1: Original and corrected Fig.
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Polyamine-dependent metabolic shielding regulates alternative splicing - Nature

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By Amaia Zabala-Letona, Saioa Garcia-Longarte, Isabel Mendizabal, Malgorzata Ewa Rogalska, Joycelyn Tan, Pilar Ximenez-Embun, Maciej Zakrzewski, Ianire Astobiza, Sarah Cherkaoui, Maria Sendino, Amaia Ercilla, Laura Bozal-Basterra, Juan A. Ferrer-Bonsoms, Joan Seoane, Rosa Barrio, James Sutherland Verified, Ana M. Aransay, Juan Manuel Falcon-Pérez, Barbara Martinez-Pastor, Francisco Blanco, Michael D. Hogarty, Raphael J. Morscher, Remigiusz A. Serwa, Jesús Jiménez-Barbero, Gonzalo Jiménez-Osés, Alejo Efeyan, Lydia W. S. Finley, Javier Muñoz, Juan Valcárcel, Maria Ponce-Rodriguez, Encarnación Pérez-Andrés, Maciej Cieśla
| Nature Verified
Abstract Metabolites are central to cellular homeostasis. Although much emphasis has been placed on their relevance to meet energetic and biosynthetic demands, metabolic intermediates also function as signalling molecules. Here we show that polyamines, small polycations that are critical to cellular homeostasis1,2,3, regulate the process of alternative pre-mRNA splicing.
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Adjusting PSC culture for neural organoid generation

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By Magdalena Sutcliffe, Pia S. Jensen, Joycelyn Tan, Charles Morris, Daniel J. Fazakerley, Martin R Larsen, Madeline A. Lancaster
| Stem Cell Reports Verified
ArticleOnline now102724Open access 1MRC Laboratory of Molecular Biology, Cambridge, UK 2Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK 3Protein Research Group, University of Southern Denmark, Odense, Denmark 4Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Cambridge, UK Publication History: Received November 19, 2024; Revised November 3, 2025; Accepted November 3, 2025; Published online December 4, 2025 DOI:...
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