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Articles by Julia Meredith
Distinct ERK and PI3K dependencies mediate a heterogeneous response to RAS(ON) inhibition in KRAS -mutant colorectal cancer
ArticleVolume 45, Issue 7117559Open access Affiliations & Notes 1Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA 2Program in Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, NY, USA 3Antitumor Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA 4Department of Biology, Revolution Medicines, Inc., Redwood City, CA, USA Article Info Publication History: Received November 22, 2025; Revised April 14, 2026;...
An appendiceal cancer organoid biobank identifies phenotypic evolution and druggable dependencies of peritoneal carcinomatosis
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Keywords peritoneal carcinomatosis appendiceal cancer organoids mouse model intratumor heterogeneity growth factor dependencies genomics targeted therapies KRAS inhibitor Introduction The peritoneal cavity is a common site of metastasis from advanced gastrointestinal and gynecological malignancies; up to 70% of patients present with peritoneal carcinomatosis (PC) at the time of metastatic diagnosis.1,2,3 PC can lead to the loss of intestinal peristalsis and organ failure, and poor overall...
By Ahmed Mahmoud, Christine Sukhwa, Michael Giarrizzo, Philip H. Choi, Jura Pintar, Henry Walch, Nan Zhao, Jonathan Bermeo, Sebastian K. Chung, Manisha Raghavan, Samhita Bapat, Qingwen Jiang, Julia Meredith, Canan Firat, Andrea Cercek, Michael Foote, Nikolaus Schultz, Walid K. Chatila, Garrett M. Nash, Jinru Shia, Francisco Sanchez-Vega, Steven M. Larson, Arvin C. Dar, Neal Rosen, Georgios Karagkounis, Karuna Ganesh
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Cell Press
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Genome-wide characterization of hypothiocyanite stress response of Escherichia coli reveals a potential role for RclB and RclC in lowering cell envelope permeability
Abstract Oxidative stress is one of the major methods of microbial population control and pathogen clearing by the mammalian immune system. The methods by which bacteria are able to escape damage by host-derived oxidants such as hydrogen peroxide (H2O2) and hypochlorous acid (HOCl) have been relatively well described, while other oxidants’ effect on bacteria and their genetic responses are not as well understood. Hypothiocyanite/hypothiocyanous acid (-OSCN/HOSCN) is one such antimicrobial oxidant.
Planned adaptation and implementation of the Community Guide recommendations for increasing physical activity in rural community settings: A qualitative study
Abstract BACKGROUND: The purpose of this paper is to report on the implementation of an evidence-based model, VIVA, which was developed to translate physical activity (PA) recommendations to rural environments and was scaled-up to 12 rural communities across New Mexico.
Frontiers | Planned adaptation and implementation of the Community Guide recommendations for increasing physical activity in rural community settings: A qualitative study
Julia M. Hess1* and Sally Davis1 1University of New Mexico, United States The final, formatted version of the article will be published soon. You just subscribed to receive the final version of the article Background The purpose of this paper is to report on the implementation of an evidence-based model, VIVA, which was developed to translate physical activity (PA) recommendations to rural environments and was scaled-up to 12 rural communities across New Mexico.
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