Juncheng Wang
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Articles by Juncheng Wang
Computer Science > Computer Vision and Pattern Recognition
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Computer Science > Computer Vision and Pattern Recognition
Forecasting the future anatomy of slow-evolving neurodegenerative diseases could enable earlier, more targeted intervention and improve clinical trial design, but it remains challenging because true progression signals are subtle in longitudinal MRI. In this low-signal regime, transferring modern generative sequence models directly is unreliable: training is dominated by stable baseline anatomy and confounded by dense, sample-specific nuisance variation.
Targeting N 1 -methyladenosine modification in osteoblasts through tRNA methyltransferase 10C reverses mitochondrial dysfunction and ameliorates osteoporosis
Abstract Osteoporosis is among the most common degenerative systemic bone diseases and is accompanied by abnormally downregulated oxidative phosphorylation (OXPHOS) in osteoblasts. While mutations in the tRNA methyltransferase (TRMT10C) gene in humans are known to cause OXPHOS dysfunction and early mortality, its role in bone homeostasis remains unknown.
Erythropoiesis–inosine metabolic axis failure underlying retinal neurodegeneration in glaucoma: novel diagnoses and therapies - Experimental & Molecular Medicine
Abstract Glaucoma, long considered an ocular-limited, age-dependent and hypoxia-driven neurodegeneration, is here reframed as a systemic erythroid–inosine axis failure that originates in the bone marrow yet culminates in retinal ganglion cell (RGC) death.
ZNF683+ NK cells govern chemotherapy sensitivity in advanced HPSCC via reshaping immune microenvironment - Nature Communications
Abstract Hypopharyngeal squamous cell carcinoma (HPSCC), an aggressive head and neck cancer with dismal prognosis, faces persistent chemoresistance to standard TPF (docetaxel, cisplatin, 5-fluorouracil) regimen. However, the immunological mechanisms underlying chemoresistance remain undefined. Here, we perform longitudinal single-cell RNA sequencing (scRNA-seq) profiling of paired pre-/post-TPF HPSCC specimens, mapping immune cell dynamics underlying chemoresistance.
Encapsulating Silicon Nanoparticles Within a 3D Interconnected Ultra‐Conductive Sodium Alginate@Ti3C2Tx Network for Robust and High‐Capacity Lithium‐Ion Batteries
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description smll72443-sup-0001-SuppMat.docx10.1 MB Supporting File: smll72443-sup-0001-SuppMat.docx. References 1 and , “Structural Changes in Silicon Anodes during Lithium Insertion/Extraction,” Electrochemical and Solid-State Letters 7 (2004): A93.
Surfactant-Triggered Alkyl-like Radical Formation in Anaerobic Thermally Activated Persulfate System for Deep Removal of Highly Chlorinated Contaminants
Cite Jump to ExpandCollapse Physico-Chemical Treatment and Resource RecoveryNovember 19, 2025 Surfactant-Triggered Alkyl-like Radical Formation in Anaerobic Thermally Activated Persulfate System for Deep Removal of Highly Chlorinated Contaminants Click to copy article linkArticle link copied! Jianhua Qu Jianhua Qu School of Resources and Environment, Northeast Agricultural University, Harbin 150030, China Jingyi Wang Jingyi Wang School of Resources and Environment, Northeast Agricultural...
[2505.23555] Adaptive Federated LoRA in Heterogeneous Wireless Networks with Independent Sampling
Work on one of the world's most important websites and make an impact on open science.
PSMC2 serves as a potential regulatory target of EZH2 in promoting glioma progression via epithelial-mesenchymal transition
Abstract Proteasome 26 S Subunit, ATPase 2 (PSMC2) was initially thought to be associated with the removal of misfolded or damaged proteins and the removal of excess proteins that are no longer necessary. However, recent studies have found that PSMC2 acts as an oncogene in the human body. In our research, PSMC2 serves as a tumor-initiating factor in glioma.
Customized Multifunctional Additive Regulates 1.67 eV‐Wide‐Bandgap Perovskite Crystallization for Four‐Terminal Perovskite/Silicon Tandem Solar Cells
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adma202503269-sup-0001-SuppMat.docx34.6 MB Supporting Information adma202503269-sup-0002-tablesS1.csv3.3 KB Supplemental Table 1 adma202503269-sup-0003-tablesS2.csv4 KB Supplemental Table 2 References 1a) , , , , J. Am. Chem. Soc. 2009, 131, 6050; b) , , , , , , , , , , Science 2020, 367, 1135; c) , , , , , , , , , , Nat. Energy. 2018, 3, 1093; d) , , , , , , , , , , Nat. Energy.
Genetic Basis of Seedling Root Traits in Common Wheat (Triticum aestivum L.) Identified by Genome-Wide Linkage Mapping
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Differential impact of TIM-3 ligands on NK cell function
Methods K562 cell line was obtained from American Type Culture Collection (Manassas, Virginia, USA).
Genome-Wide Identification of NLP Gene Families and Haplotype Analysis of SiNLP2 in Foxtail Millet (Setaria italica)
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Trajectory Planning for Lane Change with Intelligent Vehicles Using Fuzzy Logic and a Dynamic Programming and Quadratic Programming Algorithm
1. Introduction The advancement of intelligent vehicles has become a significant indicator of scientific and technological progress in recent years, with ongoing research and innovations continually driving societal development. As autonomous driving technology rapidly evolves, lane-change decision-making and trajectory planning—key components of Level 4 (L4) autonomous vehicles—have garnered increasing attention from both academia and industry [1,2].
Impact of High-Sensitivity Cardiac Troponin I Elevation after On- and Off-pump Coronary Artery Bypass Grafting on Long-term Prognosis
YTHDF2 in peritumoral hepatocytes mediates chemotherapy-induced antitumor immune responses through CX3CL1-mediated CD8+ T cell recruitment - Molecular Cancer
Z.-Y. Yang: Conceptualization, data curation, formal analysis, validation, investigation, visualization, methodology, writing–original draft, writing–reviewand editing. X.Wang: Conceptualization, data curation, formal analysis, funding acquisition, validation, investigation, writing–original draft, writing–review and editing. Y.-Z. Fu, W.-J. Wu: Resources, data curation, validation, methodology, funding acquisition, writing–review and editing. Z.-L. Hu, Q.-Y.
Growth Properties and Metabolomic Analysis Provide Insight into Drought Tolerance in Barley (Hordeum vulgare L.)
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Augmented Kalman Estimator and Equivalent Replacement Based Taylor Series-LQG Control for a Magnetorheological Semi-Active Suspension
1. Introduction The suspension system is one of the key structural and functional components for vehicles [1,2]. Compared with passive and active suspension systems, the semi-active suspension system is regarded as a more promising candidate due to its cost-effectiveness, especially for its ability to improve both ride comfort and handling stability close to the active one [3]. Recently, semi-active suspension systems featuring magnetorheological (MR) dampers have received much attention [4].
Cryo-EM structure of the Spo11 core complex bound to DNA
Abstract The DNA double-strand breaks that initiate meiotic recombination are formed by topoisomerase relative Spo11, supported by conserved auxiliary factors. Because high-resolution structural data are lacking, many questions remain about the architecture of Spo11 and its partners and how they engage with DNA. We report cryo-EM structures at up to 3.3 Å resolution of DNA-bound core complexes of Saccharomyces cerevisiae Spo11 with Rec102, Rec104, and Ski8.
A Phase Field Study of the Influence of External Loading on the Dynamics of Martensitic Phase Transformation
4.3. Dynamics Analysis of Martensitic Phase Transformation under External Loading and Plastic Deformation In order to visually observe the variation in martensite content under uniaxial loading, this study explores the effects of martensite variants and the total martensite volume fraction over time under uniaxial tensile and compressive loading. Figure 6 and Figure 7 illustrate the relationship between external loading, evolution time, and volume fraction.
Integrated Analysis of Metabolome and Transcriptome Reveals Insights for Low Phosphorus Tolerance in Wheat Seedling
4. Materials and Methods 4.1. Materials and Sample Preparation In this study, cultivated wheat G28 (LP-tolerant) and L143 (LP-sensitive), which were screened based on the laboratory’s comparative analysis of LP-tolerance in 162 wheat varieties at the seedling and planting stages, were provided by State Key Lab of Aridland Crop Science/Gansu Key Lab of Crop Improvement and Germplasm Enhancement. The field performance of these two varieties was illustrated in Supplementary Figure S1.
Efficacy of TTFields in high-grade gliomas: a protocol for systematic review and meta-analysis
Materials and methods We registered this review protocol with the PROSPERO network (registration number: CRD42023398972). The protocol will follow the statement guidelines of Preferred Reporting Items for Systematic Reviews and Meta-analyses.16 Given that this is not a prospective study, ethical approval will not be required.
Parallel Parking Path Planning in Narrow Space Based on a Three-Stage Curve Interpolation Method
With the increase in car ownership, urban parking difficulties have become increasingly prominent. The parking spaces are becoming increasingly scarce, and the available space for parking is getting narrower. Especially in parallel parking of narrow spaces, the definition is to ensure that the length of the parking space is as short as possible when the vehicles stop into a parallel parking space in one step.
LKB1 Positively Regulates Dendritic Cell-induced T Cell Immunity and Suppresses Tumor Development
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Apple Grading Based on Multi-Dimensional View Processing and Deep Learning
Author Contributions W.J.: Conceptualization, Methodology, Writing—review and editing, Project administration, Funding acquisition, Supervision. J.W.: Data curation, Validation, Writing—original draft, Formal analysis. B.X.: Visualization, Investigation, Resources. T.Z.: Methodology, Software, Writing—review and editing. All authors have read and agreed to the published version of the manuscript. Figure 1. Four-lane apple detection equipment. Figure 1. Four-lane apple detection equipment. Figure 2.
Exogenous Melatonin Enhances the Low Phosphorus Tolerance of Barley Roots of Different Genotypes
Font Type: Arial Georgia Verdana Line Spacing: Column Width: Open AccessArticle by 1,2,†, 1,2,†, 1,2, 1,2, 1,2, 1,2, 1,3, 1,2, 2, 1,2 and 1,2,* 1 State Key Lab of Aridland Crop Science/Gansu Key Lab of Crop Improvement and Germplasm Enhancement, Lanzhou 730070, China 2 Department of Crop Genetics and Breeding, College of Agronomy, Gansu Agricultural University, Lanzhou 730070, China 3 Department of Botany, College of Life Sciences and Technology, Gansu Agricultural University,...
Transcriptome and Metabolome Reveal the Molecular Mechanism of Barley Genotypes Underlying the Response to Low Nitrogen and Resupply
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Structural insights into DNMT5-mediated ATP-dependent high-fidelity epigenome maintenance
Highlights • Structures of DNMT5 reveal the mechanism of ATP-dependent DNA methylation • Hemimethylated CpG recognition triggers partial base flipping of the target cytosine • Hemimethylated DNA induces rigid body rotation to activate the SNF2 ATPase domain • SNF2 ATPase regulates the MTase activity to achieve ultrahigh specificity Summary Epigenetic evolution occurs over million-year timescales in Cryptococcus neoformans and is mediated by DNMT5, the first maintenance type cytosine...
Structural basis of ATP-dependent high-fidelity epigenome maintenance
New Results Juncheng Wang, Sandra Catania, Chongyuan Wang, M. Jason de la Cruz, Beiduo Rao, View ORCID ProfileHiten D. Madhani, Dinshaw J. Patel doi: https://doi.org/10.1101/2021.10.01.462825 SUMMARY Epigenetic evolution occurs over million-year timescales in Cryptococcus neoformans and is mediated by DNMT5, the first maintenance-type cytosine methyltransferase identified in the fungal or protist kingdoms. DNMT5 requires ATP and displays exquisite hemimethyl-DNA specificity.
DNA-driven condensation assembles the meiotic DNA break machinery
Abstract The accurate segregation of chromosomes during meiosis—which is critical for genome stability across sexual cycles—relies on homologous recombination initiated by DNA double-strand breaks (DSBs) made by the Spo11 protein1,2. The formation of DSBs is regulated and tied to the elaboration of large-scale chromosome structures3,4,5, but the protein assemblies that execute and control DNA breakage are poorly understood.
Influences of Heavy Metals and Salt on Seed Germination and Seedling Characteristics of Halophyte Halogeton glomeratus
Abstract Heavy metals pollution and salinization of soils are widely distributed in agricultural soils. This study investigated the effects of five heavy metals and five heavy metals-contaminated salt on seed germination and seedling growth of halophyte Halogeton glomeratus (H. glomeratus). The results showed that seed germination, fresh weight (FW), dry weight (DW), radicles relative viability and ion contents (Cu2+, Ni2+, Zn2+, Cd2+ and Pb2+) of H.
Structure-function analysis of microRNA 3′-end trimming by Nibbler
Structure-function analysis of microRNA 3′-end trimming by Nibbler Wei Xie, Ivica Sowemimo, Rippei Hayashi, Juncheng Wang, Thomas R. Burkard, Julius Brennecke, Stefan L. Ameres, Dinshaw J. Patel Proceedings of the National Academy of Sciences Nov 2020, 202018156; DOI: 10.1073/pnas.2018156117
The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation
Abstract The PIWI-interacting RNA (piRNA) pathway protects genome integrity in part through establishing repressive heterochromatin at transposon loci. Silencing requires piRNA-guided targeting of nuclear PIWI proteins to nascent transposon transcripts, yet the subsequent molecular events are not understood. Here, we identify SFiNX (silencing factor interacting nuclear export variant), an interdependent protein complex required for Piwi-mediated cotranscriptional silencing in Drosophila.
REC114 Partner ANKRD31 Controls Number, Timing, and Location of Meiotic DNA Breaks
Highlights • REC114 directly interacts with ANKRD31, a novel factor required for normal fertility • ANKRD31 influences the distribution of double-strand breaks genome-wide • ANKRD31 is essential for the recombination between X and Y chromosomes • A crystal structure reveals a PH domain in REC114 and its contacts with ANKRD31 Summary Double-strand breaks (DSBs) initiate the homologous recombination that is crucial for meiotic chromosome pairing and segregation.
Catalytic transfer hydrogenation of oleic acid to octadecanol over magnetic recoverable cobalt catalysts
* Corresponding authors a Key Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China E-mail: luxiuyang@zju.edu.cn b Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, & Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, School of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, P.R. China...
Catalytic transfer hydrogenation of oleic acid into octadecanol over magnetic recoverable cobalt catalysts
J. Wang, R. Nie, L. Xu, X. Lyu and X. Lu, Green Chem., 2018, Accepted Manuscript , DOI: 10.1039/C8GC03075H If you are not the author of this article and you wish to reproduce material from it in a third party non-RSC publication you must formally request permission using Copyright Clearance Center. Go to our Instructions for using Copyright Clearance Center page for details.
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