Kin Chuah Chan on Muck Rack

Kin Chuah Chan

As seen in: Nature, Yahoo Finance Singapore, The Smart Investor
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Articles

Aneuploidy selects for the acquisition of driver genes in breast cancer

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By Khalid N Al-Zahrani, Jocelyn Nurtanto, Andreea Obersterescu, Katie Teng, Christopher Lowden, Lauren Caldwell, Miguel A. Pérez-Castro, Ricky Tsai, Alexander T Bahcheli, Shifei Wu, Masahiro Narimatsu, Iosifina Fotiadou, Kin Chuah Chan, Linkang Zhang, K. W. Annie Bang, Michael Parsons, Larissa Mourao, Palavalasa Sravya, Li Zhang, Peter Sajjakulnukit, Costas A. Lyssiotis, Alexander D. Borowsky, Colinda L. G. J. Scheele, Daniel Wahl, Hartland W. Jackson, Katherine Stewart, Elaine Fuchs, Sean Egan, Miguel Angel Pujana, Jüri Reimand, Jeffrey L. Wrana, Daniel Schramek, Ellen R. Langille, Julien Dessapt, Cynthia H. Chiu, Geraldine Mbamalu, Adele G. Lopes, E. Idil Temel, Liddy McCulla
| Nature Verified
Abstract Chromosome instability is highly prevalent in cancer and drives large-scale chromosomal imbalances, known as aneuploidies1,2,3,4. How aneuploidy contributes to tumorigenesis remains difficult to study due to the vast numbers of genes affected. Here we established a CRISPR knockout- and activation-linked assay (CRISPR-KOALA), enabling high-throughput bidirectional genetic screens in immunocompetent mouse models of cancer.
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Will iFAST Hit S$100 billion in AUA by 2030? Original

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By Kin Chuah Chan
| The Smart Investor
iFAST Corporation Limited (SGX: AIY) is progressing in the right direction towards its ambitious goal of achieving assets under administration (AUA) of S$100 billion by 2030. In its 2024 first quarter (1Q 2024), iFAST reported a record AUA high of S$21.05 billion, up from over S$19.83 billion at the end of 2023. To hit S$100 billion by 2030, the fintech’s AUA will need to grow at a compounded annual growth rate (CAGR) of about 26% for the next seven years.
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