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Kirsty McHugh on Muck Rack

Kirsty McHugh

As seen in: Daily Express, HuffPost UK, Cell Reports, Cell Press, Literary Hub, City A.M., NHS England Podcast, Inside Housing, FE News, Inkl
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Articles

Addition of blood-stage antibody enhances anti-sporozoite antibody protection in a humanized mouse model of Plasmodium falciparum infection

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By Payton Kirtley, Thomas Martinson, Francesca R Donnellan, Maya Aleshnick, Bryan Mayer, Bhavesh Borate, Tzu-Jung Huang, Dimitra Pipini, Cassandra A Rigby, Doris Quinkert, Sarah Silk, Angela M Minassian, Kirsty McHugh, Simon Draper, Brandon Wilder, Kiersey Nielsen
| Cell Reports Verified
Keywords Plasmodium falciparum monoclonal antibodies circumsporozoite protein CSP RH5 317 Research topic(s) CP: immunology CP: microbiology Introduction Malaria is a vector-borne disease caused by Plasmodium parasites that are transmitted by female Anopheles mosquitoes. As of 2023, malaria remains endemic in 80 countries, resulting in approximately 610,000 annual deaths.1 Most infections are caused by two parasite species, P. falciparum (Pf) and P. vivax (Pv).
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Analysis of monoclonal antibodies against the malaria invasion complex protein RIPR reveals the structural basis for synergistic antibody protection

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By Barnabas G Williams, Jordan R. Barrett, Josefin Bartholdson Scott, Cassandra A Rigby, Matteo Cagiada, Doris Quinkert, Kirsty McHugh, Anna Huhn, Sean A. Burnap, Camille Gourjault, Francesca Byrne, Ana Rodrigues, Laura Bergamaschi, Simon Watson, Noah W. Miller, Lloyd D.W. King, Francesca R Donnellan, Camilla A. Gladstone, Sarah Silk, Jo Salkeld, Angela M Minassian, Katherine Skinner, Weston Struwe, Charlotte M. Deane, Stephen T. Reece, Andrew Ward, Simon Draper, Beatrice Balzarotti, Jemima Paterson, Stefania Scalabrino
| Cell Press Verified
Keywords malaria monoclonal antibodies RIPR vaccines Plasmodium falciparum mAb blood stage Introduction Malaria disease, caused by the parasite Plasmodium falciparum, is a global health problem with an estimated 282 million cases in 2024.1 The WHO currently recommends two malaria vaccines, RTS/S/AS01 and R21/Matrix-M2; however, both vaccines target the same pre-erythrocytic sporozoite stage of the parasite life cycle.
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How Four Literary Icons Chose the Pen Names That Made Them Famous

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By Kirsty McHugh, Ian Scott
| Literary Hub Verified
Boz Pen name of Charles Dickens (1812-1870) Charles Dickens is one of the most recognizable names in English literature, but for many years he also published as Boz. Dickens grew up in poverty, and during his childhood he had to work to help support the family during periods of financial hardship. He left school aged fifteen to work as a clerk in a solicitor’s office; he found it dull but it would later provide material for his writing.
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