Simon Draper on Muck Rack

Simon Draper

  • Professor of Vaccinology and Translational Medicine, University of Oxford
As seen in: Nature, Manawatū Standard, Stuff.co.nz, The Marlborough Express, The Nelson Mail, The Southland Times, The Timaru Herald, Cell Press, Personnel Today, Road CC and
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Articles

Wimbledons Tennisgötter

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By Simon Draper, Jonathan Ross, Billie Jean King, Miriam Margolyes
| TV Movie
Die Amerikanerin Billie Jean King setzte sich in den 70er-Jahren für Gleichberechtigung im Tennissport ein. Arthur Ashe kämpfte für Rassengleichheit auf und neben dem Platz.
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Development of clinical immunity to Plasmodium vivax following repeat controlled human malaria infection - Nature Communications

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By Mimi M. Hou, Adam Harding , Florian A. Bach, Jo Salkeld, Baktash Khozoee, Ian Poulton, Fernando Lopez, Fernando López , Doris Quinkert, Nick Edwards, Sumi Biswas, Julian C. Rayner, Simon Draper, Philip Spence, Fay L. Nugent, Lucy Kingham, Wiebke Nahrendorf
| Nature
Abstract Clinical immunity to malaria can lead to asymptomatic infection, but the underlying mechanisms remain unclear. To examine the development of clinical immunity, we conducted a multi-cohort, repeat controlled human malaria infection (CHMI) study with Plasmodium vivax, and a heterologous rechallenge with P. falciparum (ClinicalTrials.gov NCT03797989). Malaria-naïve adults underwent CHMI up to three times, by administration of red blood cells infected with P. vivax PvW1 clone or P.
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Vaccine-induced human monoclonal antibodies to PfRH5 show broadly neutralizing activity against P. falciparum clinical isolates - npj Vaccines

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By Laty G. Thiam, Yicheng Guo, Saurabh Patel, Lawrence Shapiro, Simon Draper
| Nature
Abstract Vaccines to the Plasmodium falciparum reticulocyte binding-like protein homologue 5 (PfRH5) target the blood-stage of the parasite life cycle. PfRH5 has the potential to trigger the production of strain-transcendent antibodies and has proven its efficacy both in pre-clinical and early clinical studies. Vaccine-induced monoclonal antibodies (mAbs) to PfRH5 showed promising outcomes against cultured P. falciparum laboratory strains from distinct geographic areas.
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