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Articles by Li Hou
Integrating miRNA profiling and machine learning for improved thyroid cancer diagnosis
Abstract Background: The incidence of thyroid cancer is rising significantly worldwide. It is particularly important to improve the diagnostic accuracy of thyroid cancer. This study aims to integrate miRNAs from fine needle aspiration (FNA) samples of thyroid nodules with machine learning algorithms to improve the accuracy of thyroid cancer diagnosis.
Mediating cultural identity and traditional design preferences in the acceptance of contemporary expressions within intangible cultural heritage
Abstract In the context of weakened transmission and limited adaptation of contemporary expressions of Intangible Cultural Heritage (ICH), understanding how cultural memory shapes public perception and acceptance of ICH is increasingly important. This study, grounded in cultural memory theory, aims to examine the influence of cultural memory on the acceptance of contemporary ICH expressions, with cultural identity and traditional design preferences serving as mediating mechanisms.
An evidence-weighted knowledge framework with path-aware reasoning for personalized lifestyle management in chronic disease
Abstract Background: Healthy lifestyle management is essential for chronic disease prevention and long-term care. However, evidence linking lifestyle behaviors, biological mechanisms, and health outcomes is dispersed across diverse biomedical sources. This fragmentation makes it difficult for health professionals to efficiently retrieve and interpret evidence needed to inform personalized lifestyle guidance.
Mechanically adaptive crack-resistant hydrogels based on strain-induced macroscopic phase separation and hierarchical energy dissipation
Abstract It remains a significant challenge to simultaneously achieve high stiffness, large extensibility, and strong resistance to crack propagation in hydrogels. Here, we report a hydrogel that undergoes a fully reversible strain-induced whitening transition with a high modulus ( ~ 30 MPa), high tensile strength (~15 MPa), large stretchability ( > 1000%).
Computer Science > Computer Vision and Pattern Recognition
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Cu‐Induced Structural Transformation and Electronic Modulation of Co(OH)2 Enabling Stable and Efficient Oxygen Evolution Reaction
Conflict of Interest The authors declare no conflict of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description adfm73240-sup-0001-SuppMat.docx26.5 MB Supporting Information References 1, , , , , , , , , , , , , , , Nat. Commun. 2024, 15, 5305. 2, , , , , , , , , Adv. Energy Mater. 2022, 12, 2200067. 3, , , , , , , , , , , , , Nat. Commun. 2021, 12, 3021.
Two novel mutations (c.878T>C and c.1316delA) in CD36 alleles lead to CD36 antigen deficiency
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Iron and oxygen vacancies co-modulated adsorption evolution and lattice oxygen dual-path mechanism for water oxidation - Nature Communications
Abstract Conjointly activating metal and oxygen sites to trigger the adsorbate evolution and lattice oxygen mechanisms coupled path holds promise for balancing activity and stability in oxygen evolution reaction catalysts, yet confronting great challenges. Herein, we develop Fe species and oxygen vacancies co-regulated Ni-(oxy)hydroxide from the deep reconstruction of Fe-Ni2P/NiMoO4 pre-catalyst achieving the adsorbate evolution and lattice oxygen dual-path mechanism.
Tough and Stiff Biobased Hydrogels Reinforced by Strain-Induced Ordering of Hierarchical Structure
Abstract Click to copy section linkSection link copied! Biobased hydrogels that exhibit high stiffness and notable toughness are highly sought after for mimicking load-bearing biological tissues due to their inherent biocompatibility. However, hydrogels sourced from natural polymers often display fragility and brittleness.
Competition and Cooperation in Ride-Sharing Platforms: A Game Theoretic Analysis of C2C and B2C Aggregation Strategies
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Enhanced Synthesis of Volatile Compounds by UV-B Irradiation in Artemisia argyi Leaves
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Self-derivation High-Mechanical-Strength Polymetallic Phosphides Microsheets Heterostructures for Industrial-scale High Current Density Water Splitting
Self-derivation High-Mechanical-Strength Polymetallic Phosphides Microsheets Heterostructures for Industrial-scale High Current Density Water Splitting Developing nanoarray microstructure catalysts to amplify catalytic active sites had been a prevalent strategy to achieve effective water electrolysis. However, the stability of electrodes was severely affected by the bubble bombardment at industrial condition.
Clean energy, food, water and environment: Examining COP27 targets for China's economy
REFERENCES , & (2010). On the relationship between energy consumption, CO2 emissions and economic growth in Europe. Energy, 35(12), 5412–5420. , , , & (2023). Interaction among geopolitical risk, trade openness, economic growth, carbon emissions and its implication on climate change in India. Energy & Environment, 34(5), 1305–1326. , , , , & (2023).
Enhanced Catalytic Synthesis of Flavonoid by UV-B Radiation in Artemisia argyi
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Sorcin Inhibits Mitochondrial Apoptosis by Interacting with STAT3 via NF-κB Pathway
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Engineering Tough Supramolecular Hydrogels with Structured Micropillars for Tunable Wetting and Adhesion Properties
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description smll202308570-sup-0001-SuppMat.docx1.8 MB Supporting Information References 1, , , Nat. Rev. Mater. 2017, 2, 17036. 2, , Nature 2003, 424, 852. 3, , Adv. Mater. 2018, 30, 1704696. 4, , , , , , , , , Proc. Natl. Acad. Sci. U.S.A. 2020, 117, 2282. 5, , , , , , , , , , Small 2021, 17, 2005493. 6, , , , Biosurf. Biotribol. 2018, 4, 39. 7, , , , , , , , Giant 2020, 2, 100017. 8, , , , Prog. Mater. Sci.
Integrating Multiple Regulatory Strategies：Phase, Morphology and Interface Engineering to Construct Hierarchical Ni2P-MoS2/rGO Heterostructure Catalyst for Efficient Oxygen Reduction Reaction
Integrating Multiple Regulatory Strategies：Phase, Morphology and Interface Engineering to Construct Hierarchical Ni2P-MoS2/rGO Heterostructure Catalyst for Efficient Oxygen Reduction Reaction Two-dimensional (2D) molybdenum disulfide (MoS2) with large surface area and unique electronic properties has emerged as a promising noble metal-free catalyst for electrochemical energy storage/conversion applications.
Divergent composition and transposon-silencing activity of small RNAs in mammalian oocytes - Genome Biology
We sequenced both small RNAs and mRNAs in oocytes from 12 animal species including 11 mammals (human, monkey, rabbit, guinea pig, mouse, rat, golden hamster, Chinese hamster, dog, pig, goat), representing ~ 81 million years of evolution within the eutherians (Fig. 1A). All oocytes were collected at the germinal vesicle (GV) or MII stage (Additional file 1: Fig. S1). For each species, 3–5 individual oocytes were sequenced.
Intermittent catheterization care on bladder function
Back to Journals » International Journal of General Medicine » Volume 17 Original Research General Medicine Authors Wang L, Wang F, Qin H, Hou L, Zhu S, He F, Zeng C Received 6 February 2024 Accepted for publication 9 June 2024 Published 14 June 2024 Volume 2024:17 Pages 2781—2789 DOI https://doi.org/10.2147/IJGM.S463225 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Woon-Man Kung Lin Wang,1,2 Fulan Wang,1,2 Hong...
Neuropeptide ACP is required for fat body lipid metabolism homeostasis in locusts
Supporting Information Filename Description ins13321-sup-0001-FigureS1.pdf175.9 KB Fig. S1 Pie chart of metabolite classes structurally annotated in the fat body of locusts. ins13321-sup-0002-FigureS2.pdf738 KB Fig. S2 Development processes of WT and ACP13/13 nymphs. Days required from egg hatching to 2nd, 3rd, 4th, 5th larval stages and adult stages were calculated.
An intelligent readable and capture-antibody-independent lateral flow immunoassay based on Cu2−xSe nanocrystals for point-of-care detection of Escherichia coli O157:H7
An intelligent readable and capture-antibody-independent lateral flow immunoassay based on Cu2−xSe nanocrystals for point-of-care detection of Escherichia coli O157:H7† Escherichia coli (E. coli) O157:H7 is a common foodborne pathogen which can cause serious harm. It is particularly important to establish a simple and portable method to achieve on-site pathogen detection.
Rational design of three dimensional pomegranate-shaped double layer carbon shell coated Si nanoparticles as an excellent anode material for lithium ion batteries
Rational design of three dimensional pomegranate-shaped double layer carbon shell coated Si nanoparticles as an excellent anode material for lithium ion batteries Silicon is considered a promising candidate anode material for lithium-ion batteries (LIBs) due to its high theoretical capacity and relatively low discharge potential. However, due to the low conductivity and large volume change during cycling, its practical commercial application is hindered.
An intelligent readable and capture-antibody-independent lateral flow immunoassay based on Cu2-xSe nanocrystals for point-of-care detection of Escherichia coli O157:H7
An intelligent readable and capture-antibody-independent lateral flow immunoassay based on Cu2-xSe nanocrystals for point-of-care detection of Escherichia coli O157:H7 Escherichia coli (E. coli) O157:H7 is a common foodborne pathogen with serious harm. It is particularly important to establish a simple and portable method to achieve on-site pathogen detection.
Forsythoside B alleviates osteoarthritis through the HMGB1/TLR4/NF‐κB and Keap1/Nrf2/HO‐1 pathways
CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest. REFERENCES 1, , , , , , , Lancet 2015, 386(9991), 376. 2, , , , , , , , , , Disabil. Rehabil. 2017, 39(16), 1674. 3, , , , , , Clin. Exp. Rheumatol. 2016, 34(5), 929. 4, , , , , , , , Int. Immunol. 2014, 26(6), 325. 5, , , , Bone Res. 2016, 4, 15040. 6, , , , , , Int. J. Mol. Sci. 2016, 17(12), 2042. 7, , DNA Repair 2019, 83, 102701. 8, , Immune Netw. 2018, 18(4), e27. 9, , , , , , , , J. Cell. Physiol. 2021, 236(5), 3406. 10, , , , Hum.
Formation and Destruction of Polyelectrolyte/Surfactant Complexes for the Toughening of Hydrogels
Download Hi-Res ImageDownload to MS-PowerPointCite This:Macromolecules 2023, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
A methylene blue-functionalized DNA concatemer for the construction of a turn-off fluorescent immunosensor for the sensitive detection of carcinoembryonic antigen
A methylene blue-functionalized DNA concatemer for the construction of a turn-off fluorescent immunosensor for the sensitive detection of carcinoembryonic antigen† This study showed a method of synthetization of a methylene blue-functionalized DNA concatemer via hybridization chain reaction (HCR) used for turn-off fluorescence detection of carcinoembryonic antigen (CEA).
Iodide-Mediated Etching of Gold Nanostar for the Multicolor Visual Detection of Hydrogen Peroxide
Font Type: Arial Georgia Verdana Line Spacing: Column Width: Open AccessCommunication by Yunping Lai †, Beirong Yu †, Tianran Lin * and Li Hou School of Chemistry and Pharmaceutical Sciences, State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, Guilin 541004, China * Author to whom correspondence should be addressed. † These authors contributed equally to this work.
The Circadian Clock Gene PER2 Enhances Chemotherapeutic Efficacy in Nasopharyngeal Carcinoma When Combined with a Targeted Nanosystem
The Circadian Clock Gene PER2 Enhances Chemotherapeutic Efficacy in Nasopharyngeal Carcinoma When Combined with a Targeted Nanosystem Li Hou, Hailiang Li, Haiyan Wang, Dede Ma, Jing Liu, liqiong Ma, Zhihua Wang, Zhihua Yang, Faxuan Wang and Hechun Xia Abstract Treatment failure occurs in more than 40% of advanced nasopharyngeal carcinoma (NPC) patients including local recurrence and distant metastasis due to chemoradioresistance.
A Nanosystem Loaded Perfluorohexane and Rose Bengal Coupled Upconversion Nanoparticles for Multimodal Imaging and Synergetic Chemo-Photodynamic Therapy in Cancer
A Nanosystem Loaded Perfluorohexane and Rose Bengal Coupled Upconversion Nanoparticles for Multimodal Imaging and Synergetic Chemo-Photodynamic Therapy in Cancer Theranostics is a new trend integrating diagnostic and therapeutic functions in tumor research. Theranostic nanoparticles that enable both tumor imaging and drug delivery are a promising platform for image-guided cancer therapy.
Estimation and model selection in general spatial dynamic panel data models
Thus far, researchers have mostly just monitored the body’s microbiome. Now they’re starting to modify it to treat disease.
Nitrogen-doped highly dense but porous carbon microspheres with ultrahigh volumetric capacitance and rate capability for supercapacitors
Nitrogen-doped highly dense but porous carbon microspheres with ultrahigh volumetric capacitance and rate capability for supercapacitors Junshuang Zhou,a Li Hou,a Jie Lian,b Wenbo Cheng,a Dong Wang,a Huiyang Gouc and Faming Gao*a Author affiliations * Corresponding authors a Key Laboratory of Applied Chemistry, College of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao 066004, P. R.
Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis
The Multi-Ethnic Study of Atherosclerosis (MESA) is a multi-site, longitudinal study designed to investigate the prevalence, correlates, and progression of subclinical CVD in a population cohort of 6814 participants. Since its inception in 2000, five clinic visits have collected extensive clinical, socio-demographic, lifestyle, behavior, laboratory, nutrition, and medication data15.
Novel mesoporous amorphous B-N-O-H nanofoam as electrode for capacitive dye removal from water
Novel mesoporous B-N-O-H nanofoam was prepared using CuB23 and ammonium chloride precursors under O2 in ionic liquids via a solution plasma technique. It had a large high specific surface area of 1023 m2 g?1, and exhibited high electrical conductivity of 20.8 Sm?1and good specific capacity of 184 Fg?1 in 600 mgL-1 methylene blue aqueous solution at a current density of 0.2 mAcm-2.
Synthesis of graphene-like CuB23 nanosheets with fast and stable response to H2S at ppb level detection
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Differential Requirement of the Extracellular Domain in Activation of Class B G Protein-coupled Receptors
G protein-coupled receptors (GPCRs) from the secretin-like (class B) family are key players in hormonal homeostasis and are important drug targets for the treatment of metabolic disorders and neuronal diseases. They consist of a large N-terminal extracellular domain (ECD) and a transmembrane domain (TMD) with the GPCR signature of seven transmembrane helices. Class B GPCRs are activated by peptide hormones with their C termini bound to the receptor ECD and their N termini bound to the TMD.
Differential Requirement of the Extracellular Domain in Activation of Class B G Protein-Coupled Receptors
G protein-coupled receptors (GPCRs) from the secretin-like (class B) family are key players in hormonal homeostasis and are important drug targets for the treatment of metabolic disorders and neuronal diseases. They consist of a large N-terminal extracellular domain (ECD) and a transmembrane domain (TMD) with the GPCR signature of seven transmembrane helices. Class B GPCRs are activated by peptide hormones with their C-termini bound to the receptor ECD and their N-termini to the TMD.
Global research trends and hotspots in cancer-related anemia from 2010 to 2025: a multidatabase bibliometric analysis
Abstract Background: Cancer-related anemia (CRA) is the most common hematologic complication of malignant tumors and their treatments, affecting treatment delivery, quality of life and survival. A macro-level map of the field’s knowledge structure, evolution and frontiers is still lacking.
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