Lin Kong
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Articles by Lin Kong
Carbon ion irradiation at a clinically used dose rewires super-enhancers to drive necroptosis and systemic immunity
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share This article has 0 eLetter . Abstract Radiotherapy augments immunotherapy, yet conventional 2 Gy x-ray fractions largely induce apoptosis, whereas robust immunogenic cell death (ICD) is more commonly associated with higher-dose irradiation regimens.
The gut microbiota dietary index reveals a modifiable diet–depression association varying by BMI and possibly linked to inflammation: a hypothesis-generating modified diet for future intervention research
Abstract In the context of the microbiota-gut-brain axis, diet represents a critical yet still debated component of translational psychiatry. However, population-based evidence linking microbiota-supportive dietary patterns to depressive symptoms remains limited. This research leverages the Dietary Index for Gut Microbiota (DI-GM) to examine the associations between a gut-microbiota-friendly diet and depression, providing a theoretical framework for future research on practical applications.
Distinct properties of plastic-derived submicrometer particles from smoldering burning
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Widespread plastic use and mismanaged disposal release substantial amounts of particles into the atmosphere during waste burning. We define these thermally generated particles as plastic-derived submicrometer particles (PDSPs), a poorly characterized class of contaminants.
Effects of Linker Length and Flexibility on the Activity of GH18 Chitinases in Bacteria
Cite Jump to ExpandCollapse Biotechnology and Biological TransformationsOctober 7, 2025 Effects of Linker Length and Flexibility on the Activity of GH18 Chitinases in Bacteria Click to copy article linkArticle link copied! Pengfei Li Pengfei Li MOE Key Laboratory of Bio-Intelligent Manufacturing, School of Bioengineering, Dalian University of Technology, No. 2, Linggong Road, Dalian 116024, China Lin Kong Lin Kong MOE Key Laboratory of Bio-Intelligent Manufacturing, School of Bioengineering,...
Thermal Optimization Design for a Small Flat-Panel Synthetic Aperture Radar Satellite
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Tissue‐specific alternative splicing and the functional differentiation of LmLPMO15‐1 in Locusta migratoria
Supporting Information Filename Description ins13469-sup-0001-SuppMat.docx2 MB Table S1 Primers for polymerase chain reaction (PCR) amplification and double-stranded RNA (dsRNA) synthesis. Table S2 Name of LPMO15s and accession numbers for phylogenetic analysis from the National Center for Biotechnology Information (NCBI). Table S3 Accession number of LPMO15-1s on the National Center for Biotechnology Information (NCBI) with splicing site in the middle of transcripts. Fig.
Enhancing Interface Performance Through Self-Assembly Mechanisms of APTES on Surface-Modified Tuff Aggregates
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
‘Here the people know each other’: why do so many regional Australian towns have a Chinese restaurant?
Lin Jie Kong: One night, in search of dinner towards the end of a long road trip, I found myself at the RSL club in Karuah, a sleepy bayside town just north of Port Stephens, New South Wales. I feared it would be another night of choosing between chicken parmy and fish and chips, but was surprised to find a well-reviewed Chinese restaurant in the club. All the Australian Chinese staples were there: sweet and sour pork, Mongolian lamb, beef and black bean sauce.
The only paddock-to-plate Chinese restaurant in Australia is built on a 20-year family farming adventure
T’s Chinese Restaurant Sheffield, Tasmania Alex Zhao was working the woks one night when his neighbour rang to say that one of Alex’s cows had escaped and was heading down the road. When you’re both the paddock and the plate in T’s Paddock to Plate Chinese restaurant, sometimes mid-stir-fry you just have to jump on your motorcycle and go retrieve a cow.
Heat Sink Equivalent Thermal Test Method and Its Application in Low-Orbit Satellites
1. Introduction Commercial satellite constellations not only need to achieve reliability, but also require low-cost and time-saving approaches. Among the costs of traditional satellite development, environmental tests account for about 30% to 40% of the total investment in spacecraft development [1,2]. Satellite thermal testing is the most complicated, costly, and time-consuming project in the spacecraft development process.
Aggregation-induced emission photosensitizer for antibacterial therapy of methicillin-resistant Staphylococcus aureus
Aggregation-induced emission photosensitizer for antibacterial therapy of methicillin-resistant Staphylococcus aureus A cationic aggregation-induced emission photosensitizer (AIE-PS) MNNPyBB has been reported to have antibacterial effects against both gram-positive and gram-negative bacteria. The bacterial kill mechanism has been investigated and elucidated.
A novel mitochondria‐related core gene signature to predict the prognosis and evaluate tumour microenvironment in CESC single‐cell validation
1 INTRODUCTION Cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), accounting for an estimated 570,000 new cases and 311,000 female fatalities annually in 2018, represent a leading cause of mortality in women and rank as the fourth most prevalent malignancy globally.1 China and India, with respective populations of 106,000 and 97,000, reported death rates of 48,000 and 60,000, collectively contributing to over one-third of the total CESC patient count worldwide.2...
Molecules | Free Full-Text | Biodegradable Metal Complex-Gated Organosilica for Dually Enhanced Chemodynamic Therapy through GSH Depletions and NIR Light-Triggered Photothermal Effects
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Mitochondrial-targeted fluorophore: synthesis, property and cells imaging
Mitochondrial-targeted fluorophore: synthesis, property and cells imaging† PEGylated 2-(2-(6-(dimethylamino)benzooxazol-2-yl)vinyl)quinolin-8-ol (BQ-mPEG) was synthesized, which exhibited strong fluorescence at 610 nm (ϕf = 0.11) and a large Stoke's shift (Δλ = 202 nm) in the aqueous solution. The fluorophore displayed a two-photon absorption characteristic and a strong red emission (λem = 625 nm) was observed with NIR (950 nm) irradiation.
Fluorination of naphthalimide-cyanostilbene derivatives to achieve dual-state emission luminogens with strong fluorescence in highly polar environments for bioimaging - Journal of Materials Chemistry B (RSC Publishing)
Fluorination of naphthalimide–cyanostilbene derivatives to achieve dual-state emission luminogens with strong fluorescence in highly polar environments for bioimaging† Qiusi Shi,‡a Yingyong Ni,‡a Longmei Yang,a Lin Kong, a Peiyang Gu, b Chengyuan Wang, *a Qichun Zhang, *c Hongping Zhou a and Jiaxiang Yang *a Abstract Organic luminogens (OLs) that emit strong fluorescence in both solution and the aggregated state, referred to as dual-state emission luminogens (DSEgens), are highly desirable...
Tahun Macan Air Diharapkan Mendorong Keluar dari Kesulitan
Suara.com - Tahun Baru Imlek ini mengantar Tahun Macan,khususnya, MacanAir. Berikutasal-usulnya dan apa artinya. Mitologi dan simbolisme Delia Lin, dari departemen Studi China di University of Melbourne mengatakanmeski ada prinsip umum seputar simbolMacan Air, ada juga banyak karakteristik lain. "Banyak orang menggambarkankarakteristik yang berbeda [tentang Macan Air], danitu berkaitan dengan tradisi dan kepercayaan orang.Pada dasarnya soal interpretasi," kata Dr Lin.
Particle radiation therapy in the management of malignant glioma: Early experience at the Shanghai Proton and Heavy Ion Center
Abstract Background The objective of this study was to evaluate the outcomes of patients with high‐grade glioma who received treatment with particle radiotherapy. Methods Between June 2015 and October 2018, 50 consecutive and nonselected patients with glioblastoma multiforme (n = 34) or anaplastic glioma (n = 16) were treated at the Shanghai Proton and Heavy Ion Center.
Correction: A facile strategy to realize a single/double photon excitation-dependent photosensitizer for imaging-guided phototherapy against HeLa cancer cells at separate irradiation channels
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A facile strategy to realize a single/double photon excitation-dependent photosensitizer for imaging-guided phototherapy against HeLa cancer cells at separate irradiation channels
A facile strategy to realize a single/double photon excitation-dependent photosensitizer for imaging-guided phototherapy against HeLa cancer cells at separate irradiation channels† Lin Kong, *a Ze Huang,a Shuai-Shuai Zhang,a Jian Song,b Yu-Yang Zhang,a Xiang-Yang Bai,a Jia-Xiang Yang *a and Lin Li *c Author affiliations * Corresponding authors a College of Chemistry and Chemical Engineering, Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials,...
A facile strategy to realize single/double photon excitation- dependent photosensitizer for imaging-guided phototherapy against HeLa cancer cells at separated irradiation channels
A facile strategy to realize single/double photon excitation- dependent photosensitizer for imaging-guided phototherapy against HeLa cancer cells at separated irradiation channels A novel difluoroboron fluorophore with electronic donor-acceptor conjugated structure was synthesized with 26.5% fluorescent quantum yield, 18035 GM two-photon absorbing cross-section, and undetectable two-photon fluorescence, resulting in 25% 1O2 quantum yield.
In vivo two-photon imaging/excited photothermal therapy strategy of a silver-nanohybrid
In vivo two-photon imaging/excited photothermal therapy strategy of a silver-nanohybrid† A multi-functional nanohybrid (PyAnOH-Ag) with both a two-photon photothermal therapy (TP-PTT) effect and two-photon excited fluorescence (TPEF) imaging performance has been fabricated based on interfacial coordination interactions. The hybrid possesses a high two-photon absorption cross section (δTPA, 4638 GM) and detectable TPEF signals, which leads to excellent two-photon photothermal conversion.
A Novel Fusion of ALT-803 (Interleukin (IL)-15 Superagonist) with an Antibody Demonstrates Antigen-specific Antitumor Responses
IL-15 and its receptor ? (IL-15R?) are co-expressed on antigen-presenting cells, allowing transpresentation of IL-15 to immune cells bearing IL-2R?? and stimulation of effector immune responses. We reported previously that the high-affinity interactions between an IL-15 superagonist (IL-15N72D) and the extracellular IL-15R? sushi domain (IL-15R?Su) could be exploited to create a functional scaffold for the design of multivalent disease-targeted complexes.
A novel fusion of ALT-803 (IL-15 Superagonist) with an antibody demonstrates antigen-specific antitumor responses
Interleukin (IL)-15 and its receptor α (IL-15Rα) are co-expressed on antigen-presenting cells allowing transpresentation of IL-15 to immune cells bearing IL-2RβγC and stimulation of effector immune responses. We previously reported that the high-affinity interactions between an IL-15 superagonist (IL-15N72D) and the extracellular IL-15Rα sushi domain (IL-15RαSu) could be exploited to create a functional scaffold for the design of multivalent disease-targeted complexes.
Effect of solvent, pH and metal ions on the self-assembly process and optical properties of an A-π-D-π-A type triphenylamine carboxylic acid derivative - Journal of Materials Chemistry C (RSC Publishing)
A ‘Λ’ structural A–π–D–π–A type triphenylamine derivative (2E,2′E)-3,3′-(4,4′-(phenylazanediyl)bis(4,1-phenylene))diacrylic acid (abbreviated as L) with intramolecular charge transfer (ICT) character has been designed, synthesized and characterized. The morphology and linear optical properties of L nanostructures can be tuned by changing the solvent and/or the acidity of the solution.
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