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Articles by Ling Yao
Factors associated with severe COVID-19 among children aged <12 years in Fuzhou, China: a frequency-matched case-control study
Abstract Background: Evidence on social, preventive, and clinical factors associated with severe pediatric COVID-19 remains limited in regional Chinese surveillance settings. We evaluated these factors among children aged <12 years in Fuzhou. Methods: We conducted a frequency-matched case-control study of 347 severe cases and 694 non-severe controls identified from sentinel hospitals and the China Disease Prevention and Control Information System between January 2020 and August 2025.
The metabolic-inflammatory axis in chronic heart failure: integrating the NLR and TyG index for recent-onset atrial fibrillation prediction via machine learning and mediation analysis
Abstract Introduction: Recent-onset atrial fibrillation (AF) is a common complication of chronic heart failure (CHF), potentially involving both inflammatory and metabolic dysregulation. This study aimed to develop and externally validate an interpretable machine learning (ML) model for predicting recent-onset AF in patients with CHF and to explore the relationships among inflammatory dysregulation, metabolic dysregulation, and recent-onset AF.
A machine learning model for diabetic retinopathy risk stratification using routine blood and urine parameters: insights into kidney-eye crosstalk
Abstract Objective: This study aimed to develop and externally validate an interpretable machine learning (ML) model for diabetic retinopathy (DR) risk stratification using routine clinical biomarkers, and to explore potential probabilistic dependencies and interactive pathways between clinical biomarkers and DR pathogenesis through Bayesian network modeling.
Exploring predictors of low nutritional literacy in maintenance hemodialysis patients: a machine learning and network analysis approach
Abstract Background: Patients undergoing maintenance hemodialysis (MHD) commonly experience substantial self-care challenges due to the complexity and highly restrictive nature of their treatment regimens. Nutritional literacy is a critical determinant of effective self-management in this population. However, the main predictors of low nutritional literacy and their relationships remain unclear, limiting early targeted interventions.
Impact of demographic, clinical, and viral factors on severe influenza in young children in Fuzhou
Abstract Background: Identify risk factors for severe influenza in children under 5 years of age in the Fuzhou region to provide evidence-based support for early identification of high-risk patients, optimization of Pediatric Intensive Care Unit (PICU) resource allocation, and development of targeted intervention strategies. Methods: A total of 386 severe influenza cases and 1,544 non-severe cases among children under 5 years old in Fuzhou City were collected from January 2015 to January 2025.
Advancing solar and wind penetration in China through energy complementarity
Abstract The intrinsic variability of solar and wind energy, compounded by their rapid expansion, has intensified power curtailment challenges1,2. Although spatiotemporal complementarity between these resources is widely recognized as a pathway to enhance renewable integration and reduce balancing requirements3,4,5,6,7,8,9,10,11,12,13,14,15,16, existing assessments are largely based on hypothetical deployments17,18,19,20,21,22,23,24.
Accelerated Himalayan river meandering and dynamics due to climate change
Editor’s summary Structured Abstract Abstract Supplementary Materials References and Notes Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Editor’s summary High mountain ranges are particularly sensitive to climate change, and their landscapes provide an early warning for how surface processes may shift with warming. Using 40 years of satellite imagery, Lin et al.
Association between aldosterone and the risk of cardiovascular disease in hypertensive patients: a cohort study
Abstract Objective: Whether plasma aldosterone concentration (PAC) is associated with incident cardiovascular disease (CVD) remains unclear in hypertensive patients, particularly after excluding those with primary aldosteronism. This study evaluates the association between PAC and incident CVD. Methods: This study included hypertensive patients admitted to the hypertension center between January 1, 2014, and December 31, 2017, who had PAC measurements.
Three novel diazotrophic species, Paenibacillus oryziterrae sp. nov., Paenibacillus paludis sp. nov. and Paenibacillus diazotrophicus sp. nov., isolated from red paddy soil with potential for consortium-based rice growth promotion
Volume 76, Issue 4 Article metrics loading... /content/journal/ijsem/10.1099/ijsem.0.007124 Metrics References Bueno Batista M, Dixon R. Manipulating nitrogen regulation in diazotrophic bacteria for agronomic benefit. Biochem Soc T 2019; 47:603–614 [View Article] [Google Scholar] Tang R, Yang S, Narsing Rao MP, Xie C-J, Han S et al. Three Fe(III)-reducing and nitrogen-fixing bacteria, Anaeromyxobacter terrae sp. nov., Anaeromyxobacter oryzisoli sp. nov. and Anaeromyxobacter soli sp.
Building façade photovoltaics enhance global climate resilience
Abstract Climate change is intensifying global energy demands and amplifying exposure to extreme heat. Building façade-integrated photovoltaics (FIPV) present a largely untapped opportunity to supply renewable electricity while enhancing urban climate resilience.
Honey dressing for diabetic foot ulcers: a systematic review and meta-analysis of randomized controlled trials
Abstract Background: To systematically evaluate the efficacy and safety of honey dressing compared to conventional dressings in the treatment of DFUs. Methods: We conducted a systematic review and meta-analysis following PRISMA guidelines. PubMed, BIOSIS, EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL), and Google Scholar internet were searched from inception to Jan 31, 2026 for RCTs comparing honey dressing with conventional dressings in DFU patients.
Optimization of efficient preparation process and structural characterization of Holoferritin based on biosynthetic pathways
Food and Fermentation Industries ›› 2026, Vol. 52 ›› Issue (4) : 77-83. DOI: 10.13995/j.cnki.11-1802/ts.042892 Optimization of efficient preparation process and structural characterization of Holoferritin based on biosynthetic pathways {{javascript:window.custom_author_en_index=0;}} {{article.zuoZhe_EN}} Author information History Download Citations {{article.zuoZheEn_L}}. {{article.title_en}}[J].
New Strategy for Cluster‐Based Covalent Organic Framework: Thermally Induced Covalent Crosslinking of Highly Stable Copper Clusters
1 Introduction Over the past half century, increasing consumption of fossil fuels has caused a sharp increase in the concentration of CO2 in the atmosphere, exacerbating the greenhouse effect and leading to global warming.[1, 2] Artificial solar-driven CO2 and H2O reduction to renewable fuels is one of the most promising approaches for producing carbon-neutral energy and addressing the global greenhouse effect.[3, 4] At present, the photocatalysts most reported for the CO2 reduction reaction...
Globally interconnected solar-wind system addresses future electricity demands - Nature Communications
Abstract Accelerating energy transition towards renewables is central to net-zero emissions. However, building a global power system dominated by solar and wind energy presents immense challenges. Here, we demonstrate the potential of a globally interconnected solar-wind system to meet future electricity demands. We estimate that such a system could generate ~3.1 times the projected 2050 global electricity demand.
Micheliolide Alleviates Hepatic Fibrosis by Inhibiting Autophagy in Hepatic Stellate Cells via the TrxR1/2-Mediated ROS/MEK/ERK Pathway
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Morin Improves the Bone Histomorphology and Biochemical Markers in an Animal Model of Ovariectomy‐Induced Osteoporosis by Suppressing Autophagy and Apoptosis
1 Background Osteoporosis (OP) is a chronic disorder known as the most common skeletal pathological state that affects millions worldwide. It is characterized by a substantial decrease in bone density, leading to a weakening of the bone structure and disruption in the normal architecture of the skeletal system, which affects people of all ages, genders, and ethnic backgrounds (Langdahl 2021; Tu et al. 2018).
Carbon sequestration potential of tree planting in China - Nature Communications
Abstract China’s large-scale tree planting programs are critical for achieving its carbon neutrality by 2060, but determining where and how to plant trees for maximum carbon sequestration has not been rigorously assessed. Here, we developed a comprehensive machine learning framework that integrates diverse environmental variables to quantify tree growth suitability and its relationship with tree numbers. Then, their correlations with biomass carbon stocks were robustly established.
Roofing Highways With Solar Panels Substantially Reduces Carbon Emissions and Traffic Losses
1 Introduction Replacing fossil fuels with renewable energy sources has become a critical priority on the global agenda (Davis Steven et al., 2018; Luderer et al., 2018).
Differential expression and clinical significance of IGF2BP3 in peritoneal dialysate of patients with varying duration of peritoneal dialysis
WHAT IS THE CURRENT KNOWLEDGE ON THE TOPIC? Current knowledge indicates that chronic peritoneal dialysis (PD) could lead to peritoneal fibrosis (PF), a significant complication that affects the longevity and effectiveness of PD treatment.
Evaluation of the ocular safety of hollow MSNs
Juan Li,1,* Ziqing Gao,1,* Ning Li,1 Ling Yao,1 Chao Liu,1 Che Xu,1 Xiaohui Ren,1 Aiqin Wang,1 Siqi Gao,2 Miao Wang,2 Xiang Gao,2 Kun Li,3 Jianfeng Wang1 1Department of Ophthalmology, First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, 233004, People’s Republic of China; 2School of Clinical Medicine, Bengbu Medical University, Bengbu, Anhui, 233004, People’s Republic of China; 3School of Life and Health Science, Anhui Science and Technology University, Fengyang,...
A ML prediction model of adult obstructive sleep apnea
Jiewei Huang,1,2 Jiajing Zhuang,2,3 Huaxian Zheng,4 Ling Yao,5,6 Qingquan Chen,7,8 Jiaqi Wang,1,2 Chunmei Fan1 1The Clinical Laboratory Center of the Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, 362018, People’s Republic of China; 2The Graduate School of Fujian Medical University, Fuzhou, Fujian Province, 350108, People’s Republic of China; 3Department of Ultrasound, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, 350001, People’s...
The protective effects of Phoenixin-20 in tumor necrosis factor α (TNF-α)-induced cell senescence of rheumatoid arthritis fibroblast-like synoviocytes (FLS) | Aging
Research Paper Volume 15, Issue 24 pp 14607—14616 1 Department of Hematology and Rheumatology, The First Hospital of Nanchang, Nanchang, Jiangxi 330008, China 2 Department of Gastroenterology, The First Hospital of Nanchang, Nanchang, Jiangxi 330008, China 3 Department of Gerontology, The First Hospital of Nanchang, Nanchang, Jiangxi 330008, China 4 Department of Rheumatology and Immunology, The First Hospital of Nanchang, Nanchang, Jiangxi 330008, China https://doi.org/10.18632/aging.205024...
The protective effects of Phoenixin-20 in tumor necrosis factor α (TNF-α)-induced cell senescence of rheumatoid arthritis fibroblast-like synoviocytes (FLS) | Aging
Research Paper Volume 15, Issue 24 pp 14607—14616 1 Department of Hematology and Rheumatology, The First Hospital of Nanchang, Nanchang, Jiangxi 330008, China 2 Department of Gastroenterology, The First Hospital of Nanchang, Nanchang, Jiangxi 330008, China 3 Department of Gerontology, The First Hospital of Nanchang, Nanchang, Jiangxi 330008, China 4 Department of Rheumatology and Immunology, The First Hospital of Nanchang, Nanchang, Jiangxi 330008, China https://doi.org/10.18632/aging.205024...
Differential expression of KIF18B in gastric cancer and its role in chemotherapy sensitivity
, DOI: 10.1615/CritRevEukaryotGeneExpr.2023049523 Get access Li-Hong Gan The First Hospital of Nanchang (The Third School of Clinical Medicine, Nanchang University) Ling Yao The First Hospital of Nanchang (The Third School of Clinical Medicine, Nanchang University) Jin-Hua Yan The First Hospital of Nanchang (The Third School of Clinical Medicine, Nanchang University) Ya-Qin Huang The First Hospital of Nanchang (The Third School of Clinical Medicine, Nanchang University) Li Zheng The First...
Application of Dynamic Enhanced Magnetic Resonance Imaging Texture Analysis Combined with ADCs in Predicting Pelvic Lymph Metastasis of Prostate Cancer
Ling Yao [1] ; Jia Ding [2] ; Xueying Li [2] ; Jie Yang [1] ; Zhentao Chen [3] ; Changkai Jia [4] ; Qinghong Duan [1] [1] Department of Radiology, The Affiliated Cancer Hospital of Guizhou Medical University, 550001 Guiyang, Guizhou, China [2] Department of Medical Imaging, Guizhou Medical University, 550025 Guiyang, Guizhou, China [3] MR Clinical Research Department, Canon Medical Systems (China) Co., Ltd., 100015 Beijing, China [4] MR Clinical Application Department, Canon Medical System...
Water temperature and organic carbon control spatio‐temporal dynamics of particle‐attached and free‐living bacterial communities in a hypereutrophic urban river network
DATA AVAILABILITY STATEMENT The raw sequence data in this study were submitted to the National Center for Biotechnology Information (NCBI) Sequence Read Archive (SRA) under accession number PRJNA847357 (first year) and PRJNA847387 (second year). The data supporting the conclusions of this article are included within the article.
Spatial−temporal variation of ecological environment quality and driving factors from 2000 to 2020 in Wuliangsu Lake Basin, Northern China
1 Introduction Eco-environmental quality assessment is essential for quantitatively measuring the strengths, weaknesses and impacts of regional ecological environments (Balsamo et al., 2015). It is a significant basis for formulating regional socio-economic sustainable development plans and eco-environmental protection measures, and also a crucial assessment for the stability of ecosystems in desertification areas (Sun et al., 2015).
Time to voluntarily self-disclose? What to know about DOJ’s recent policy revisions | White Collar Corner
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Quantifying knowledge from the perspective of information structurization
PLOS ONE, Jan 2023 This is a preview of a remote PDF: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0279314&type=printable Xinbing Wang, Huquan Kang, Luoyi Fu, Ling Yao, Jiaxin Ding, Jianghao Wang, Xiaoying Gan, Chenghu Zhou, John E. Hopcroft. , PLOS ONE, 2023, Volume 18, Issue 1, DOI: 10.1371/journal.pone.0279314
Functional Au array SERS chip for pesticides fast inspection in conjunction with surface extraction and coordination transferring
Functional Au array SERS chip for pesticides fast inspection in conjunction with surface extraction and coordination transferring Fast inspection of pesticides residue on the fruits and vegetables needs the development of facile, sensitive and accurate methods. Surface enhanced Raman scattering (SERS) is promising to provide fast inspection methods, which require a significant improvement in the reproducibility and feasibility.
Characterization of <i>PIK3CA</i> and <i>PIK3R1</i> somatic mutations in Chinese breast cancer patients
Here, we sought to provide a landscape of non-synonymous somatic mutations of PI3K pathway in Chinese breast cancer patients. Our cohort included 149 patients ranging from 25 to 72 years of age who were pathologically confirmed at Fudan University Shanghai Cancer Center (FUSCC). The patients’ clinicopathological parameters are listed in Supplementary Table 1. In all, 32 (21.5%) of the patients were Luminal A, 75 (50.3%) were Luminal B, 17 (11.4%) were HER2-enriched, and 25 (16.8%) were TNBC (Fig.
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