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Liying Yang on Muck Rack

Liying Yang

As seen in: Nature, Wiley Online Library, arXiv, Frontiers, MDPI, Science Magazine, Royal Society of Chemistry, BioRxiv, Cell Press, Cell Reports and
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Articles

Plasticity of extrachromosomal DNA segregation during drug adaptation

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By Chikako Shibata, Kenichi Miyata, Marwa Akao, Kohei Kumegawa, Yumiko Maruyama, Liying Yang, Ryu-Suke Nozawa, Toru Hirota, Shingo Iwami, Shoya Iwanami, Reo Maruyama, Mana Nagamoto
| Nature Verified
Abstract Uneven segregation during mitosis is a striking feature of extrachromosomal DNA (ecDNA). Because ecDNA lacks a centromere, it is thought to segregate stochastically, generating intratumoral heterogeneity in genomic copy number. Drug treatment can readily change ecDNA copy number, enabling cells to acquire drug resistance, yet whether these changes reflect static selection of pre-existing clones or active reconfiguration under stress remains unresolved.
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CFTR-driven immune microenvironment reprogramming synergizes with anti-PD-L1 antibody in hepatocellular carcinoma

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By Yijia Xu, Jianfang Sun, Yuying Lu, Yujie Fan, Liying Yang, Mengying Zhang, Xin Zhe Liu, Lijuan Kong, Yanfeng Liu, Yang Su, Mingyi Zhao, Chongyang He, Yipin Xie, Jinghai Zhang
| Nature Verified
Abstract Immune checkpoint inhibitors, notably PD-1/PD-L1 monoclonal antibodies, are now used as first-line treatments for hepatocellular carcinoma (HCC) and have improved outcomes for some patients. Nevertheless, their response rate remains below 30%, largely due to HCC’s immunosuppressive microenvironment and insufficient T-cell infiltration. Strategies to address these limitations are urgently needed.
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Reactive reconstruction and embedded passivation of heterointerfaces for intrinsically stable perovskite photovoltaics

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By Youngmin Ko, John Hintze, Luise Fast, Zhixin Ren, Jike Ding, Yuan Qiu, Huanqi Cao, Cong Chen, Shifu Zhang, Ulrich Wilhelm Paetzold, Jinzhao Li, Qian Zhao, Liying Yang, Shougen Yin, Jijian Lian
| Science Magazine Verified
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Heterointerface degradation under operational stress represents a critical limitation to perovskite solar cell longevity.
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