Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Articles by Longlong Wang
A designed ubiquitin-binding protein selectively enriches and visualizes unanchored ubiquitin
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share This article has 0 eLetter . Abstract While protein ubiquitination has been extensively studied, the roles of unanchored ubiquitin and its chains remain less understood, largely due to a lack of specific, high-affinity tools for their enrichment and visualization.
Unlocking Zn-Ion Diffusion in Disordered Rocksalt Cathodes for Nonaqueous Zn-Ion Batteries
1 Introduction The growing global demand for energy storage has driven interest in sustainable and low-cost alternatives to lithium-ion batteries. Multivalent battery systems based on ions such as Zn2+, Mg2+, Ca2+, and Al3+ are particularly attractive due to their high theoretical energy density arising from multi-electron transfer [1, 2].
R-NTN: a robust detection method for Ethereum phishing attacks based on multi-dimensional transaction features
Blockchain technology, proposed by Satoshi Nakamoto in 2008, has garnered widespread attention due to its characteristics of decentralization, immutability, transparency, anonymity, security, and programmability (Nakamoto, 2008). Blockchain does not rely on any central authority or third-party trust; instead, it maintains a reliable database through a distributed ledger system, with all participants jointly maintaining the integrity of the database (Iansiti & Lakhani, 2017).
IRF2BPL transcriptionally regulates IGFBP2 to promote tumor progression and suppresses immune cell infiltration in esophageal squamous cell carcinoma - Oncogene
Abstract Numerous ubiquitination-related proteases (URPs) have been identified as facilitators of disease progression through the disruption of ubiquitination homeostasis in substrate proteins. Notably, some URPs have exhibited non-classical biological functions.
Nutrient stress diverts RRN3 from rRNA transcription to alternative polyadenylation of autophagy mRNAs in ovarian cancer - Cell Death & Disease
Abstract Stress-induced alternative processing of mRNA is emerging as an essential mechanism to drive almost every hallmark of cancer. Through a genome-wide screening based on an abnormal transcriptional readthrough event favoring the malignant progression of ovarian carcinoma (OC), we identified novel mRNA processing regulators including RRN3, an essential factor for the transcriptional initiation of rRNA.
Association of novel sleep EEG biomarkers with All-Cause Mortality in | NSS
Back to Journals » Nature and Science of Sleep » Volume 17 Authors Huang J, Wang L Received 5 August 2025 Accepted for publication 15 November 2025 Published 22 November 2025 Volume 2025:17 Pages 3015—3032 DOI https://doi.org/10.2147/NSS.S557087 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Prof.
Efficient Red-Emitting Carbon Dots and Albumin Composites for Precise Synovial Bioimaging in Rheumatoid Arthritis
Efficient Red-Emitting Carbon Dots and Albumin Composites for Precise Synovial Bioimaging in Rheumatoid Arthritis Rheumatoid arthritis (RA) is a chronic autoimmune disorder that frequently leads to significant disabilities and requires complex therapeutic strategies. Early detection and accurate monitoring of synovial lesions are crucial for effective treatment; however, the development of targeted imaging probes remains a significant challenge.
Differential Adjuvant Activity by Flagellins from Escherichia coli, Salmonella enterica Serotype Typhimurium, and Pseudomonas aeruginosa
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
A Security-Oriented Data-Sharing Scheme Based on Blockchain
1. Introduction Data sharing facilitates knowledge dissemination, enhances collaborative research endeavors, and advances the public interest. Data sharing can make full use of data resources by sharing one’s data for others to use [1], reduce the cost of data collection, maximize the social benefits of similar data, and also help to improve the reproducibility and verifiability of data and enhance the credibility and scientific value of research results.
Foods | Free Full-Text | Determination of Free Glycidol and Total Free Monochloropropanediol in Fish and Krill Oil with Simple Aqueous Derivatization and High-Performance Liquid Chromatography-Tandem Mass Spectrometry
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Understanding the Roles of Aerosols and Clouds in Environment, Meteorology and Climate with Advanced Lidar Remote Sensing Techniques
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Investigation of the Combination Mechanism of Spontaneous Imbibition and Water Flooding in Tight Oil Reservoirs Based on Nuclear Magnetic Resonance
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
HDAC6/aggresome processing pathway importance for inflammasome formation is context dependent
Abstract The inflammasome is a large multiprotein complex that assembles in the cell cytoplasm in response to stress or pathogenic infection. Its primary function is to defend the cell and promote the secretion of pro-inflammatory cytokines, including IL-1β and IL-18.
Aerosol Optical Properties Retrieved by Polarization Raman Lidar: Methodology and Strategy of a Quality-Assurance Tool
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
IGH repertoire analysis at scale: deciphering the complexity of B cell infiltration and migration in esophageal squamous cell carcinoma - Cancer Gene Therapy
Abstract Tumor-infiltrating B-lineage cells have become predictors of prognosis and immunotherapy responses in various cancers. However, limited knowledge about their infiltration and migration patterns has hindered the understanding of their anti-tumor functions. Here, we examined the immunoglobulin heavy chain (IGH) repertoires in 496 multi-regional tumor, 107 normal tissue, and 48 metastatic lymph node samples obtained from 107 patients with esophageal squamous cell carcinoma (ESCC).
Friction and wear characteristics of β‐Sialon prepared from secondary aluminum dross
CONFLICT OF INTEREST STATEMENT The authors declare that they have no known competing financial interests or personal relationships that could have influenced the work reported in this paper. REFERENCES 1, , , , . Synthesis of silica nanoparticles from sugarcane bagasse ash and nano-silicon via magnesiothermic reactions. Ceram Int. 2019; 45. 2, , , . Mineralogy and thermal expansion study of mullite-based ceramics synthesized from coal fly ash and aluminum dross industrial wastes. Ceram Int. 2019; 45.
High-energy all-solid-state lithium batteries enabled by Co-free LiNiO2 cathodes with robust outside-in structures - Nature Nanotechnology
Abstract A critical current challenge in the development of all-solid-state lithium batteries (ASSLBs) is reducing the cost of fabrication without compromising the performance. Here we report a sulfide ASSLB based on a high-energy, Co-free LiNiO2 cathode with a robust outside-in structure.
Performance of Wide Dynamic Photomultiplier Applied in a Low Blind Zone Lidar
3. Results and Discussion For two-minute data sampling, the backscattered lidar signals were collected by the WDPM, which are divided into one PC channel and two analog channels (). Obviously, the PC signal is saturated below about 500 m in the near range. Although the analog signal in the low dynamic range channel showed better performance in the near range detection (below 200 m), it is still saturated to compare with the analog signal in the high dynamic range channel.
HDAC6/aggresome processing pathway importance for inflammasome formation is context dependent
Abstract The inflammasome is a large multiprotein complex that assembles in the cell cytoplasm in response to stress or pathogenic infection. Its primary function is to defend the cell and promote the secretion of pro-inflammatory cytokines, including IL-1beta and IL-18.
Mycobacterium smegmatis, A Promising Vaccine Vector for Preventing TB and Other Diseases: Vaccinomics Insights and Applications
Altmetric share Share announcement Help format_quote Cite thumb_up ... Endorse textsms ... Comment Need Help? Support Find support for a specific problem in the support section of our website. Get Support Feedback Please let us know what you think of our products and services. Give Feedback Information Visit our dedicated information section to learn more about MDPI.
Heme catabolism mediated by heme oxygenase in uninfected interstitial cells enables efficient symbiotic nitrogen fixation in Lotus japonicus nodules
Filename Description nph19074-sup-0001-Supinfo.pdfPDF document, 2.1 MB Fig. S1 UPLC-MS/MS identification of heme and biliverdin. Fig. S2 Sequence alignment of the HO1 and HO2 protein families. Fig. S3 Expression and protein subcellular localization of LjHO2. Fig. S4 LjHO1 gene knockout by CRISPR/Cas9. Fig. S5 Symbiotic phenotypes of ho1 mutants in Gifu background. Fig. S6 Characterization of melanin-like pigments of ho1 brown nodules. Fig.
Chemoproteomic target deconvolution reveals Histone Deacetylases as targets of (R)-lipoic acid - Nature Communications
Abstract Lipoic acid is an essential enzyme cofactor in central metabolic pathways. Due to its claimed antioxidant properties, racemic (R/S)-lipoic acid is used as a food supplement but is also investigated as a pharmaceutical in over 180 clinical trials covering a broad range of diseases. Moreover, (R/S)-lipoic acid is an approved drug for the treatment of diabetic neuropathy. However, its mechanism of action remains elusive.
Treatment acceptance of telemedicine in patients with OSA
Back to Journals » Nature and Science of Sleep » Volume 15 Authors Pei G , Ou Q, Lao M, Wang L, Xu Y, Tan J, Zheng G Received 7 April 2023 Accepted for publication 27 July 2023 Published 4 August 2023 Volume 2023:15 Pages 607—622 DOI https://doi.org/10.2147/NSS.S416221 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Dr Valentina Alfonsi Guo Pei,1,2,* Qiong Ou,1,2,* Miaochan Lao,1 Longlong Wang,1 Yanxia Xu,1...
Distinct phenotypic clusters of sleep‐disordered breathing and their association with medical care‐seeking behaviour and sleep habits: the Guangdong Sleep Health Study
RESEARCH ARTICLE Funding information: National Natural Science Foundation of China, Grant/Award Numbers: 81870077, 82170098; the CAMS Innovation Fund for Medical Sciences, Grant/Award Number: 2020-I2M-2-009 Summary Sleep-disordered breathing (SDB) is highly prevalent, but its rates of diagnosis and treatment are low. As a heterogeneous condition, it is associated with delayed diagnosis and/or suboptimal treatment.
Disrupting the HDAC6-ubiquitin interaction impairs infection by influenza and Zika virus and cellular stress pathways
Method details Nanobody screens and preparation The target protein was a 6xHis- and HALO-tagged human HDAC6 ZnF (aa 1106–1215, expressed from plasmid pHis6HaloTag-hHDAC6ZnF) which was prepared by expression in E. coli BL21(DE3) RIL+. As a control, 6xHis-HALO protein (expressed from plasmid pH6HTN His6HaloTag) was prepared in a similar manner. Cells were induced with 0.5 mM IPTG at 20°C for 20 h. E.
Metastable Facet-Controlled Cu2WS4 Single Crystals with Enhanced Adsorption Activity for Gaseous Elemental Mercury
Purposively designing environmental advanced materials and elucidating the underlying reactivity mechanism at the atomic level allows for the further optimization of the removal performance for contaminants. Herein, using well facet-controlled I-Cu2WS4 single crystals as a model transition metal chalcogenide sorbent, we investigated the adsorption performance of the exposed facets toward gaseous elemental mercury (Hg0).
In-situ visualization of the space-charge-layer effect on interfacial lithium-ion transport in all-solid-state batteries
Abstract The space charge layer (SCL) is generally considered one of the origins of the sluggish interfacial lithium-ion transport in all-solid-state lithium-ion batteries (ASSLIBs). However, in-situ visualization of the SCL effect on the interfacial lithium-ion transport in sulfide-based ASSLIBs is still a great challenge.
Identification of Variable and Joining Germline Genes and Alleles for Rhesus Macaque from B Cell Receptor Repertoires
Wei Zhang, Xinyue Li, Longlong Wang, Jianxiang Deng, Liya Lin, Lei Tian, Jinghua Wu, Chenling Tang, Huanming Yang, Jian Wang, Ping Qiu, Tong-Ming Fu, Nitin K. Saksena, I-Ming Wang and Xiao Liu J Immunol March 1, 2019, 202 (5) 1612-1622; DOI: https://doi.org/10.4049/jimmunol.1800342 Abstract The rhesus macaque is a valuable preclinical animal model to estimate vaccine effectiveness and is also important for understanding Ab maturation and B cell repertoire evolution responding to vaccination.
Identification of Variable and Joining Germline Genes and Alleles for Rhesus Macaque from B Cell Receptor Repertoires
Wei Zhang, Xinyue Li, Longlong Wang, Jianxiang Deng, Liya Lin, Lei Tian, Jinghua Wu, Chenling Tang, Huanming Yang, Jian Wang, Ping Qiu, Tong-Ming Fu, Nitin K. Saksena, I-Ming Wang and Xiao Liu J Immunol January 30, 2019, ji1800342; DOI: https://doi.org/10.4049/jimmunol.1800342 Abstract The rhesus macaque is a valuable preclinical animal model to estimate vaccine effectiveness and is also important for understanding Ab maturation and B cell repertoire evolution responding to vaccination.
Reviving lithium cobalt oxide-based lithium secondary batteries-toward a higher energy density
By breaking through the energy density limits step-by-step, the use of lithium cobalt oxide-based Li-ion batteries (LCO-based LIBs) has led to the unprecedented success of consumer electronics over the past 27 years. Recently, strong demands for the quick renewal of the properties of electronic products every so often have resulted in smarter, larger screened, more lightweight devices with longer standby times that have pushed the energy density of LCO-based LIBs nearly to their limit.
Show More
loading
Actions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with Longlong
Contact Longlong, search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck Rack