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Articles by Lu Meng
Prediction models for post-induction hypotension in patients undergoing general anesthesia: a systematic review and meta-analysis
Abstract Background: Post-induction hypotension (PIH) is a frequent perioperative complication during general anesthesia and adversely affects patient outcomes. Although machine-learning techniques have been widely applied to develop PIH prediction models, the methodological quality and predictive performance of existing models lack systematic evaluation.
Knock Off переносит дух ретро-игрушек в динамичный файтинг с тактическими поединками
Разработчики представили Knock Off — динамичный файтинг, вдохновленный атмосферой игрушек 80-х и 90-х годов. Игроков ждет мир оживших пластиковых фигурок, где сражения разворачиваются на стилизованных аренах, а каждый поединок требует не только хорошей реакции, но и грамотного планирования. Каждый боец обладает уникальным набором приемов, собственными преимуществами, недостатками и индивидуальным стилем ведения боя.
From patient-derived tumor organoids to personalized cancer therapy: advancing treatment for advanced solid tumors
Abstract Background: Cancer remains a major global public health burden, with high morbidity and mortality. Despite advances in treatment strategies, many patients with advanced solid tumors face treatment resistance and limited therapeutic options. Patient-derived tumor organoids (PDTOs) have emerged as promising preclinical models for personalized medicine, but their clinical translational potential in guiding individualized treatment for advanced solid tumors requires further validation.
Influenza Vaccination Coverage Among Nursing Home Residents and Health Care Personnel — United States, 2024–25 Influenza Season
Methods HCP employment categories. Beginning with the 2022–23 influenza season, nursing homes in the United States have been required by CMS to report influenza vaccination among HCP to CDC’s NHSN at the end of each season.
Multi-ACPNet: A multi-scale sequence-structure feature fusion framework for anticancer peptide identification and functional prediction
2. Methods For the first task (predicting whether a peptide is an ACP), we employ three datasets: the ACP-Mixed-80 [21], AntiCP 2.0_Main and AntiCP 2.0_Alternate [8]. The ACP-Mixed-80 dataset was constructed by integrating multiple benchmark datasets [8,25–28], followed by rigorous preprocessing including label verification, label correction or removal, duplicate elimination, and separation of positive and negative samples. Sequences with > 80% similarity were further removed using CD-HIT [29].
From Graduation to Retirement: How Life-Role Transition Cue Advertising Shape Consumer Preferences for Self-Improvement Products
Abstract Marketing communications substantially influence consumers’ perspectives and choices. Yet, the comparative efficacy of advertisements that incorporate life-role transition cues remains largely unexplored. This paper delves into the effects of life-role transition cue advertising on consumer preferences for self-improvement products by examining various life events, including graduation, marriage, parenthood, and retirement.
Wearing bacteriophages individually with an adhesive drug-loadable nanohelmet for treating ocular infections
Abstract Ocular infections pose notable blindness risks. Despite its advantages in inhibiting multidrug-resistant bacteria and eliminating biofilms, phage therapy suffers low phage vitality, limited ocular retention, and lack of anti-inflammatory abilities toward ocular infections. Here, wearing phages individually with an adhesive drug-loadable nanohelmet is reported to advance phage therapy.
Enhancing phage therapy by coating single bacteriophage-infected bacteria with polymer to preserve phage vitality - Nature Biomedical Engineering
Abstract The efficacy of bacteriophages in treating bacterial infections largely depends on the phages’ vitality, which is impaired when they are naturally released from their hosts, as well as by culture media, manufacturing processes and other insults.
Simultaneous Detection of Eight Dairy-Derived Components Using Double-Tube Multiplex qPCR Based TaqMan Probe
1. Introduction The issue of identifying the animal species origin of milk and dairy products has garnered growing interest, particularly in relation to traceability, allergic reactions, and the provision of precise consumer information. Milk is an excellent and highly nutritious dietary component that is abundant in protein, essential fatty acids, vitamins, calcium, and potassium, among other minerals [1].
The busier, the better? The effect of a busy mindset on the preference for self‐improvement products
CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest. Supporting Information Filename Description mar22115-sup-0001-Appendix_1.docx812.1 KB Supporting information. REFERENCES (2017). The epic of America. Routledge. , & (2015). Cross-domain effects of guilt on desire for self-improvement products. Journal of Consumer Research, 42(3), 401–419. , , & (2017). Functions of positive emotions: Gratitude as a motivator of self-improvement and positive change. Emotion Review, 9(3), 183–190.
Fully heavy tetraquark resonant states with different flavors
We use the quark potential model to calculate the mass spectrum of the S-wave fully heavy tetraquark systems with different flavors, including the bcb¯c¯,bbc¯c¯,ccc¯b¯, and bbb¯c¯ systems. We employ the Gaussian expansion method to solve the four-body Schrödinger equation, and the complex scaling method to identify resonant states. The bcb¯c¯,bbc¯c¯,ccc¯b¯, and bbb¯c¯ resonant states are obtained in the mass regions of (13.2, 13.5), (13.3, 13.6), (10.0, 10.3), (16.5, 16.7) GeV, respectively.
Survival Predictive Nomograms for Non-Surgical Brain Metastases Patients From Non-Small Cell Lung Cancer Receiving Radiotherapy: A Population-Based Study
OBJECTIVE: A high number of Non-Small Cell Lung Cancer (NSCLC) patients with brain metastasis who have not had surgery often have a negative outlook. Radiotherapy remains a most common and effective method. Nomograms were developed to forecast the cancer-specific survival (CSS) and overall survival (OS) in NSCLC individuals with nonoperative brain metastases who underwent radiotherapy.
Solving the left-hand cut problem in lattice QCD: ${T}_{cc}(3875{)}^{+}$ from finite volume energy levels
We discuss a novel effective-field-theory-based approach for extracting two-body scattering information from finite volume energies, serving as an alternative to Lüscher’s method. By explicitly incorporating one-pion exchange, we overcome the challenging left-hand cut problem in Lüscher’s method and can handle finite volume energy levels both below and above the left-hand cut.
Spectrum of the molecular pentaquarks
We investigate the mass spectrum of the molecular pentaquarks composed of a baryon and a meson. We establish the underlying relations among the near-threshold interactions of the molecular tetraquark and pentaquark systems. We find the existence of the molecule candidates in the ΣcD¯(*), DD*, and DD¯* systems indicates a substantial presence of the hadronic molecules in the heavy baryon plus heavy meson systems (heavy refers to the hadrons with the c and/or s quarks).
PD‐L1 inhibitors combined with whole brain radiotherapy in patients with small cell lung cancer brain metastases: Real‐world evidence
1 INTRODUCTION Small cell lung cancer (SCLC) is a malignant and aggressive tumor originating from the mucous membrane of the lungs or from the gland.1 Patients with SCLC often have poor clinical outcomes due to the high risk of the cancer spreading to the brain.
Doubly heavy tetraquark states in the constituent quark model using diffusion Monte Carlo method
We use the diffusion Monte Carlo (DMC) method to calculate the doubly heavy tetraquark Tcc system in two kinds of constituent quark models, the pure constituent quark model AL1/AP1 and the chiral constituent quark model. When the discrete configurations are complete and no spatial clustering is predetermined, the AL1/AP1 model gives an energy of Tcc close to the DD* threshold, and the chiral constituent quark model yields a deeply bound state.
Benchmark calculations of fully heavy compact and molecular tetraquark states
We calculate the mass spectrum of the S-wave fully heavy tetraquark systems QQQ¯Q¯(Q=c,b) with both normal (JPC=0++,1+−,2++) and exotic (JPC=0+−,1++,2+−) C-parities using three different quark potential models (AL1, AP1, BGS). The exotic C-parity systems refer to the ones that cannot be composed of two S-wave ground heavy quarkonia. We incorporate the molecular dimeson and compact diquark-antidiquark spatial correlations simultaneously, thereby discerning the actual configurations of the states.
Virtual states in the coupled-channel problems with an improved complex scaling method
We improve the complex scaling method (CSM) to obtain virtual states, which is challenging in the conventional CSM. Our approach solves the Schrödinger equation in momentum space as an eigenvalue problem by choosing flexible contours. It proves to be highly effective in identifying the poles across different Riemann sheets in multichannel scatterings.
Unified description of the $Qs\overline{q}\overline{q}$ molecular bound states, molecular resonances, and compact tetraquark states in the quark potential model
We calculate the mass spectrum of the Qsq¯q¯ (Q=c, b) tetraquark states with JP=(0,1,2)+ using the AL1 quark potential model, which successfully describes the conventional hadron spectrum. We employ the Gaussian expansion method to solve the four-body Schrödinger equation and use the complex scaling method to identify the resonances.
Molecular evolution of the rbcS multiple gene family in Oryza punctata
Conflict of Interest The authors declare that they have no conflicts of interest. Supporting Information The following supplementary material is available online for this article at http://onlinelibrary.wiley.com/doi/10.1111/jse.13039/suppinfo: Filename Description jse13039-sup-0001-Supplemental_Materials.pdf782 KB Fig. S1. Predicted protein tertiary structures of OprbcS1, OprbcS2&5, and OprbcS3&4. Fig. S2.
Tetraquark bound states in constituent quark models: Benchmark test calculations
We investigate the tetraquark bound states that are manifestly exotic using three distinct few-body methods; Gaussian expansion method (GEM), resonating group method (RGM), and diffusion Monte Carlo (DMC). We refer to manifestly exotic states that do not involve a mixture with the conventional mesons through the creation and annihilation of nn¯, where n=u, d.
SODCNN: A Convolutional Neural Network Model for Small Object Detection in Drone-Captured Images
1. Introduction Small object detection finds ubiquitous applications in the real world across various domains. In the realm of intelligent transportation, accurate detection of small objects or distant entities such as traffic signs, vehicles, and pedestrians is imperative for ensuring safe autonomous driving [1]. In the field of aerial remote sensing, precise localization and classification of objects of interest are paramount for critical response and urban monitoring [2,3,4].
Dual-Guided Brain Diffusion Model: Natural Image Reconstruction from Human Visual Stimulus fMRI
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by * and College of Information Science and Engineering, Northeastern University, Shenyang 110000, China * Author to whom correspondence should be addressed.
Prone position ventilation for the relief of acute respiratory distress syndrome through improved pulmonary ventilation: Efficacy and safety
Filename Description nicc12948-sup-0001-Supinfo.zipZip archive, 1.2 MB Data S1 Supporting Information. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Blockchain Security Mechanism Design Based on Chinese Cryptosystem SM2 Algorithm
3.3.2. Compensation for Differences Using Prime-Based Addition Chains Using prime numbers smaller than 2w − 1 as a replacement for odd numbers introduces differences. For example, when the window width is set to 5, the Fw-NAF algorithm requires 11 precomputed points, whereas the w-NAF window algorithm requires 16 precomputed points. There is a discrepancy between the two, which needs to be compensated for using prime-based addition chains.
Ground state baryons in the flux-tube three-body confinement model using diffusion Monte Carlo
Abstract We make a systematical diffusion Monte Carlo (DMC) calculation for all ground state baryons in two confinement scenarios, the pairwise confinement and the three-body flux-tube confinement. With the baryons as an example, we illustrate a feasible procedure to investigate the few-quark states with possible few-body confinement mechanisms, which can be extended to the multiquark states easily.
A Spike-destructing human antibody effectively neutralizes Omicron-included SARS-CoV-2 variants with therapeutic efficacy
Structural analysis reveals Ab08 engaging RBD at an epitope away from RBM To accurately characterize the Ab08 epitope, we crystalized the Ab08 scFv (scAb08) in complex with RBD in the space group of P21 and determined the crystal structure to a resolution of 2.8 Å (Fig 3A and S1 Table). The structure was refined to Rwork/Rfree of 0.2198/0.2509 without geometry outliers.
Identification of oogonial stem cells in chicken ovary
3.3 The maintenance of germline potential and expression of pluripotency markers in cultured OSCs Next, we tried to isolate the putative OSCs from chicken ovaries with the magnetic-assisted cell sorting (MACS) by using the DDX4 and SSEA-1 antibodies. The current DDX4-based MACS did not yield enough authentic cells for further functional analysis, possibly due to the lack of species cross-reactivity of the DDX4 antibody.
Factors Associated with Delayed or Missed Second-Dose mRNA COVID-19 Vaccination among Persons <span class=
In December 2020, the US Food and Drug Administration (FDA) issued Emergency Use Authorizations (EUAs) for the Pfizer BioNTech (https://www.pfizer.com) and Moderna (https://www.modernatx.com) 2-dose primary mRNA COVID-19 vaccine series (1,2).
Polyethyleneimine-complexed charge-reversed yeast cell walls for enhanced oral delivery of pseudovirus-based antigens
Polyethyleneimine-complexed charge-reversed yeast cell walls for enhanced oral delivery of pseudovirus-based antigens Oral vaccination has wide applicability in poor areas, particularly during the epidemic period of infectious diseases. However, successful oral antigen delivery and immune activation remain highly challenging due to the instability of vaccines in gastric acid and low capture of antigens in the intestine.
The Working Mothers Raising Children on the Assembly Line
HUBEI, Central China — Every day, Huang Hongxia’s son makes his homework to the background music of her and her colleagues’ incessantly whirring sewing machines. Huang, 42, works in the factory of “Plus Ten” clothing, in Wuhan’s mostly rural Huangpi District. Every day at 8 a.m., she gets on her bicycle and takes her young son to school before heading to work at the factory. Later in the day, she’ll pop out during her shift to pick him up after class.
Measles vaccination in infants younger than 9 months
Yi Huang Lu Meng Hai-Lu Zhao In their meta-analyses, Laura Nic Lochlainn and colleagues, 2 Nic Lochlainn LM de Gier B van der Maas N et al. Effect of measles vaccination in infants younger than 9 months on the immune response to subsequent measles vaccine doses: a systematic review and meta-analysis. Lancet Infect Dis.
Correction: Confined Co9S8 into a defective carbon matrix as a bifunctional oxygen electrocatalyst for rechargeable zinc-air batteries
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Confined Co9S8 into Defective Carbon Matrix as Bifunctional Oxygen Electrocatalyst for Rechargeable Zinc-Air Battery
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In situ fluorescent profiling of living cell membrane proteins at single-molecule level
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Engineered Glycocalyx Regulates Stem Cell Proliferation in Murine Crypt Organoids
At the base of the intestinal crypt, long-lived Lgr5+ stem cells are intercalated by Paneth cells that provide essential niche signals for stem cell maintenance. This unique epithelial anatomy makes the intestinal crypt one of the most accessible models for the study of adult stem cell biology. The glycosylation patterns of this compartment are poorly characterized, and the impact of glycans on stem cell differentiation remains largely unexplored.
Modulating Cell-Surface Receptor Signaling and Ion Channel Functions by In Situ Glycan Editing
Glycans anchored on cell-surface receptors are active modulators of receptor signaling. A strategy is presented that enforces transient changes to cell-surface glycosylation patterns to tune receptor signaling. This approach, termed in?situ glycan editing, exploits recombinant glycosyltransferases to incorporate monosaccharides with linkage specificity onto receptors in?situ.
One-Step Selective Exoenzymatic Labeling (SEEL) Strategy for the Biotinylation and Identification of Glycoproteins of Living Cells
Technologies that can visualize, capture, and identify subsets of biomolecules that are not encoded by the genome in the context of healthy and diseased cells will offer unique opportunities to uncover the molecular mechanism of a multitude of physiological and disease processes. We describe here a chemical reporter strategy for labeling of cell surface glycoconjugates that takes advantage of recombinant glycosyltransferases and a corresponding sugar nucleotide functionalized by biotin.
The FBPase Encoding Gene glpX Is Required for Gluconeogenesis, Bacterial Proliferation and Division In Vivo of Mycobacterium marinum
Citation: Tong J, Meng L, Wang X, Liu L, Lyu L, Wang C, et al. (2016) The FBPase Encoding Gene glpX Is Required for Gluconeogenesis, Bacterial Proliferation and Division In Vivo of Mycobacterium marinum. PLoS ONE 11(5): e0156663. doi:10.1371/journal.pone.0156663 Copyright: © 2016 Tong et al.
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