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Yingying Su

As seen in: Nature, Wiley Online Library, Memory Studies, New Phytologist, ScienceDirect, Frontiers, MDPI, SAGE Publishing, ACS Publications, Royal Society of Chemistry and
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Articles

Lateral septum GABAergic neurons mediate the effects of dexmedetomidine on allodynia and sleep in a male mouse model of neuropathic pain

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By Yingying Su, Jie Deng, Meiying Chen, Kaibin Wu, Peiwen Tang, Chen Wang, Deyi Kong, Ting Xu, Feixue Liang, Wenjun Xin, Yan Wu, Xia Feng, Haiting Fan, Zhengkai Liang
| Nature Verified
Abstract Chronic pain and sleep disorders frequently co-occur and exacerbate each other, yet the neural mechanisms underlying this comorbidity remain poorly understood. Here, we found that hyperactivity of GABAergic neurons in the dorsal division of the lateral septum (LSGABA) drives both pain-like behavior and sleep disruption induced by spared nerve injury (SNI) in male mice.
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Adipocyte-specific ablation of Gadd45b exacerbates obesity-associated cellular senescence and metabolic disorders via Fgf1b promoter hypermethylation

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By Fan Hu, Ningning Bai, Jun Xu, Yikai Wang, Yingying Su, Jingjing Sun, Xuhong Lu, Wenfei Li, Rongrong Xu, Tingting Hu, Miriayi Alimujiang, Junfeng Han, Ling Wu, Ying Yang, Yafen Ye
| Nature Verified
Abstract Cellular senescence contributes to obesity-associated adipose dysfunction, yet the upstream regulators of this process remain poorly understood. Here, we identified growth arrest and DNA damage-inducible protein 45 beta (Gadd45b) as an adaptive regulator of adipocyte senescence and systemic metabolic homeostasis. GADD45B expression was elevated in adipose tissue from obese human subjects and positively correlated with senescence-related markers.
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Apple ZAT11, a C2H2-type zinc finger protein, enhances resistance to Penicillium expansum by affecting jasmonic acid biosynthesis in apple

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By Yuchun Lu, Kaili Wang, Yingying Su
| New Phytologist
Data availability The data supporting this study are available in Supporting Information Tables . All relevant data can be found within the manuscript and its supporting materials.
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