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Articles by Mark Schattner
Pembrolizumab and olaparib in homologous-recombination-deficient metastatic pancreatic cancer: the phase 2 POLAR trial
Abstract Homologous recombination deficiency (HRD) arising from BRCA1or BRCA2 or PALB2 mutations confers sensitivity to platinum chemotherapy and PARP inhibition in pancreatic cancer (PC) and may enable prolonged disease control with immune checkpoint blockade (ICB). The phase 2 POLAR trial evaluated maintenance pembrolizumab plus olaparib following platinum-based chemotherapy in biomarker-stratified metastatic PC.
LONG-TERM OUTCOMES OF GASTRIC PER-ORAL ENDOSCOPIC PYLOROMYOTOMY (G-POEM) FOR DELAYED GASTRIC EMPTYING FOLLOWING IVOR-LEWIS ESOPHAGECTOMY
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Achieving Promotion for Junior Faculty in Academic Medicine: An Interview With Experts
Academic medicine plays a crucial role at the crossroads of medical practice, education, and research, influencing the future landscape of healthcare. Many physicians aspire to pursue and sustain a career in academic medicine to contribute to the advancement of medical knowledge, enhance patient care, and influence the trajectory of the medical field.
FEASIBILITY OF SALVAGE ESOPHAGEAL ENDOSCOPIC SUBMUCOSAL DISSECTION FOR REFRACTORY ESOPHAGEAL CANCER WITH PRIOR RADIATION THERAPY
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Indications for Total Gastrectomy in CDH1 Mutation Carriers and Outcomes of Risk-Reducing Minimally Invasive and Open Gastrectomies
Original Investigation September 30, 2020 JAMA Surg. 2020;155(11):1050-1057. doi:10.1001/jamasurg.2020.3356 Key Points Question What is the likelihood of signet ring cell cancer in patients with a germline CDH1 variant who undergo total gastrectomy according to family history?
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