Skip To Main Content
Martin Beck on Muck Rack

Martin Beck

  • Founder,MB Productions and Digital Product Strategist, Claremont McKenna College
Los Angeles
As seen in: Nature, Search Engine Land, BioRxiv, Cell Press, Good Therapy, Better Programming, MarTech, Credit Strategy
Marketing and Communications @SokaUniv. formerly, Claremont McKenna College, @thirddoormedia, @latimes.

Get in touch with Martin

Contact Martin, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Articles

Molecular architecture of heterochromatin at the nuclear periphery of primary human cells

|
By Jan Philipp Kreysing, Sergio Cruz-León, Johannes W. Betz, Carlotta Penzo, Tomas Majtner, Markus Schreiber, Marina Lusic, Gerhard Hummer, Martin Beck
| Nature Verified
Abstract In eukaryotes, meters of DNA are packaged into micrometer scale nuclei. Nucleosomes, as the major organizational unit, have been extensively studied in vitro, yet the elaborate 3D structure of chromatin inside cells and its distinct oligo-nucleosome arrangements remain poorly resolved. Here, we combine cryo-electron tomography with template matching, subtomogram averaging and molecular simulations to visualize nucleosomes and chromatin structure inside human cells.
Open in Who Shared Issue with article?

The small GTPase Ran defines nuclear pore complex asymmetry

|
By Jenny Sachweh, Mandy Börmel, Sven Klumpe, Anja Becker, Reiya Taniguchi, Eva Kaindl, Jürgen Plitzko, Florian Wilfling, Martin Beck, Bernhard Hampoelz, Marta Anna Kubańska, Verena Pintschovius
| Cell Press Verified
Keywords nuclear pore complex in situ structural biology Ran GTPase biogenesis nuclear envelope asymmetry nucleoporins cryo-ET heterogeneity Introduction Eukaryotic cells use nuclear pore complexes (NPCs) to mediate and regulate nucleocytoplasmic transport across the nuclear envelope (NE). NPCs are ∼60–120 MDa macromolecular complexes composed of multiple copies of about 30 nucleoporins (Nups).
Open in Who Shared Issue with article?

In situ evidence for systematic membrane thickness variation across cellular organelles

|
By Stefanie Böhm, Martin Beck, Desislava Glushkova
| BioRxiv
Abstract In eukaryotes, membrane-bound organelles create distinct molecular environments. The compartmentalizing lipid bilayer is a dynamic composite material, whose thickness and curvature modulate the structure and function of membrane proteins. In vitro, bilayer thickness correlates with lipid composition. Cellular membranes in situ, however, are continuously remodeled and the spatial variation of their biophysical properties remains understudied.
Open in Who Shared Issue with article?
See all 789 articles