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Michael Barnes on Muck Rack

Michael Barnes

London
As seen in: Nature, Memory Studies, BMJ Open, MDPI, BioRxiv, Cell Press, Berkeleyside, medRxiv, Scientific Research Publishing (SCIRP), InsideSources and
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Articles

The SjD Map: an interactive pathway tour into Sjögren’s disease signalling mechanisms

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By Sacha E Silva-Saffar, Xavier Mariette, Jacques-Eric Gottenberg, Michele Bombardieri, Divi Cornec, Marta Alarcon-Riquelme, Michael Barnes, Sandra Ng, Wan-Fai Ng, Gaetane Nocturne, Anna Niarakis
| Nature Verified
Abstract Sjögren’s disease (SjD) remains a major unmet medical challenge, characterised by biological complexity, patient heterogeneity, and the absence of curative treatments. To advance mechanistic understanding and support therapeutic discovery, we developed a comprehensive Molecular Interaction Map (MIM).
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Multidisciplinary prediction of running-related injuries using machine learning - npj Digital Medicine

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By Han Wu, Katherine Brooke-Wavell, Michael Barnes, Zainab Awan, Sarabjit Mastana, Sam Allen
| Nature Verified
Abstract The causes of endurance running-related injury (RRI) are multifactorial, yet little research has been conducted which utilizes multidisciplinary risk factors for individualized RRI prediction. This paper presents a machine learning (ML)-ready RRI weekly prediction dataset using evidence-based multidisciplinary risk factors.
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Transcriptomic profiling and machine learning uncover gene signatures of psoriasis endotypes and disease severity - Communications Medicine

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By Henry J Grantham, Graham Smith Verified, David Watson, Simon Cockell, Rafael Henkin, Tom Ewen, Shoba Amarnath, Sandra Ng, Paolo Zuliani, Nick Dand, Kathleen Smith, Paola Di Meglio, Catherine Smith, Michael Barnes, Nick Reynolds
| Nature Verified
Abstract Despite increased understanding of psoriasis pathogenesis, molecular classification of clinical phenotypes and disease severity is poorly defined. Knowledge gaps include whether molecular endotypes of psoriasis underlie distinct clinical phenotypes and the positive and negative molecular regulators of disease severity across tissue compartments.
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