Na Lin
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Articles by Na Lin
Distribution Patterns and Community Assembly of Soil Nematodes Along Elevation Gradients in a Dry-Hot Valley
1 Introduction Arid ecosystems are highly vulnerable to climate change due to poor soil fertility and sparse vegetation (Bradford et al. 2020). At the same time, climate models predict that the frequency, intensity, and geographic extent of droughts will continue to increase across the globe (Masson-Delmotte et al. 2021). This trend underscores the growing importance of understanding the interactions among organisms inhabiting drought ecosystems.
Metabolomics reveals how culture cycles affect muscle quality changes in offshore vessel-farmed Larimichthys crocea
Abstract To explore the correlation between culture cycles and quality of offshore vessel-farmed Larimichthys crocea (initial weight: 505.32 ± 35.34 g), this study analyzed muscle quality changes at 0 (TK0, control group), 1 (TK1), 2 (TK2), 3 (TK3) and 4 (TK4) months via metabolomics.
Heritability, pregnancy determination, and clinical follow-up in fetal copy number variation: an eight-year single-center retrospective study
Abstract Copy number variation (CNV) is defined as a > 1-kb-long DNA fragment copy number increase or decrease, with fetal CNV judgment and genetic counseling posing difficulties. We tested and retrospectively analyzed fetuses using chromosomal microarray analysis (CMA), 169 with abnormal CNV being completely verified and followed up for pregnancy and postnatal outcomes. Among the 169 fetuses, 103 and 66 exhibited inherited and de novo CNV.
TMC8 is associated with a paradoxical immune landscape and promotes clear cell renal cell carcinoma progression
Abstract Background: Clear cell renal cell carcinoma (ccRCC) progression is closely linked to a complex tumor microenvironment (TME), yet key regulators remain unclear. This study aimed to systematically investigate the roles of TMC8 in ccRCC, focusing on its immunological and biological potential. Methods: Multi-cohort transcriptomic data were integrated to analyze TMC8 expression and prognostic value.
Dual Roles of Free Fatty Acids in Gout Pathogenesis: Inflammatory Drivers and Metabolic Mediators
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions. References 1, , and , “Global Epidemiology of Gout: Prevalence, Incidence, Treatment Patterns and Risk Factors,” Nature Reviews Rheumatology 16, no. 7 (2020): 380–390. 2, , , et al., “Gout,” Lancet 397, no.
Association between free fatty acids and vascular calcification in CKD patients
Abstract Purpose: As an independent risk factor for cardiovascular events in patients with chronic kidney disease (CKD), the mechanism of vascular calcification (VC) remains unclear, and current treatments targeting known mechanisms have still failed to reduce its occurrence. The relationship between free fatty acids (FFAs) and vascular calcification has been confirmed in general population in recent years, but not in CKD patients.
Nitrous Oxide-Plasma Silicon Oxide Coupled with Carbon-Incorporated Polycrystalline Silicon Enables Highly Passivated TOPCon Solar Cells Click to copy article link Article link copied!
Functional Inorganic Materials and DevicesMay 25, 2026 Zunke Liu Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences (CAS), Ningbo 315201, China Ruoyi Wang Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences (CAS), Ningbo 315201, China Na Lin Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences (CAS), Ningbo 315201, China Hongkai Zhou Ningbo Institute of Materials Technology and Engineering,...
Engineering waxy wheat with customized starch properties by integrated breeding and identification of key residues governing Granule-bound starch synthase I TaGBSSI function
DATA AVAILABILITY STATEMENT The data supporting the findings of this study are available within the article and its supplementary information files. Supporting Information Filename Description jsfa70732-sup-0001-Supplementary_Figures and Table.docxWord 2007 document , 1.3 MB Figure S1. Tissue culture and rapid generation advancement process for backcross progenies. (A) Hybridization between SM133 and WN15 under greenhouse conditions. (B) Embryo excision under sterile conditions.
Carbon-incorporated polysilicon interconnection layer enables robust self-assembled monolayer anchoring for perovskite/TOPCon tandem solar cells
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Abstract Due to the deficiency of anchoring sites (i.e., hydroxyl groups), self-assembled monolayers (SAMs) pose a significant challenge for achieving dense and uniform coverage on textured substrates, thereby hindering the development of perovskite/silicon tandem solar cells. Here, we develop an in-situ carbon incorporation strategy for polysilicon-based tunnel recombination interconnection layers to enhance SAM adsorption and anchoring.
By Haojiang Du, Huan Li, Zedong Lin, Zhenhai Yang, Xin Li Verified, Haofan Ma, Meili Zhang, Weichuang Yang, Na Lin, Xuefeng Hu, Wei Liu, Zhen Jia, Zhiqin Ying, Yuheng Zeng, Jichun Ye, Chenxu He
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Nature
Verified
Highland environment and genetic background are associated with myopia risk in Tibetans and Hans
Abstract This study aimed to investigate the relationship of high-altitude environmental features and ethnic Tibetan background with myopia. This cross-sectional study was conducted at highland and lowland sites. The highland sites were located on the Chinese Tibetan Plateau, approximately 4000 m above sea level. A total of 3634 Tibetans and 377 Hans were included in the highland group.
Clinical Outcomes of Fetal Ventriculomegaly: A Retrospective Analysis from a Tertiary Referral Center
Danhua Guo,1,2 Shuqiong He,1,2 Na Lin,1,2 Yifang Dai,1,2 Ying Li,1,2 Liangpu Xu,1– 3 Xiaoqing Wu1– 4 1Department of Medical Genetic Diagnosis and Therapy Center, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian, People’s Republic of China; 2Fujian Provincial Key Laboratory of Prenatal Diagnosis and Birth Defect, Fuzhou, Fujian, People’s Republic of China; 3Department of Laboratory...
Genetic etiology and pregnancy outcomes of abnormal fluid accumulation in fetus: A retrospective cohort study
Loading metrics Open Access Peer-reviewed Research Article Citation: Cai M, Lin N, Su L, Fu M, Huang H, Xu L (2025) Genetic etiology and pregnancy outcomes of abnormal fluid accumulation in fetus: A retrospective cohort study. PLoS One 20(12): e0337437.
Identification of a Novel MTM1 Mutation Associated with X-Linked Myotubular Myopathy: Clinical and Molecular Insights for Prenatal Diagnosis
Back to Journals » International Journal of Women's Health » Volume 18 Authors Chen S , Liang B , Lin N, Pan M , Li L Received 2 December 2025 Accepted for publication 12 March 2026 Published 18 March 2026 Volume 2026:18 Pages 1—8 DOI https://doi.org/10.2147/IJWH.S585909 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Matteo Frigerio Shixin Chen,1,* Bin Liang,1,* Na Lin,1 Mian Pan,2 Li Li2 1Medical Genetic...
Distributed Fusion Filtering for Multi‐Sensor Multi‐Rate Systems With Packet Disorders Under Hybrid Cyber Attacks
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement Data sharing is not applicable to this article as no datasets were generated or analyzed during the current study. References 1, , , et al., “Multi-Sensor Fusion and Cooperative Perception for Autonomous Driving: A Review,” IEEE Intelligent Transportation Systems Magazine 15, no. 5 (2023): 36–58.
Frontiers | Optimizing pediatric AKI diagnosis: a patient-tailored meta-analysis of urinary TIMP-2/IGFBP7 performance across clinical scenarios and assay platforms
1Youjiang Medical University for Nationalities Department of Pediatrics, Affiliated Hospital of Youjiang Ethnic Medical College, Baise, China 2Youjiang Medical University for Nationalities, Baise, China Objective: To systematically evaluate the diagnostic value of urinary cell cycle arrest biomarkers, tissue inhibitor of metalloproteinases-2 (TIMP-2) and insulin-like growth factor binding protein 7 (IGFBP7), for the early diagnosis of acute kidney injury (AKI) in children using a meta-analysis.
Mesothelin as a biomarker and potential therapeutic target in rheumatoid arthritis bone destruction
The TET3/GATA6 Axis Drives Lipid Metabolism and Therapeutic Vulnerabilities in Pancreatic Ductal Adenocarcinoma (Adv. Sci. 37/2025)
Graphical Abstract Pancreatic Ductal Adenocarcinoma In article number 2501774, Ruiyu Xie and co-workers demonstrate that TET3 plays a non-canonical role in regulating lipid metabolism in pancreatic ductal adenocarcinoma (PDAC) by recruiting histone deacetylases (HDACs) to repress GATA6. This repression sustains the expression of lipogenic enzymes (SCD, FASN, ACSL3) and promotes resistance to ferroptosis.
Dual‐Layer Transcriptional‐Protein Regulation by HvAP2‐12 Represses HvAP2‐18 Activity to Fine‐Tune Barley Starch Synthesis
1 Introduction Barley (Hordeum vulgare L.) is the world's fourth-largest crop and is widely used in beer brewing and feed production. Starch is the major storage component of barley grains, constituting 50%–70% of the grain dry weight (Hu et al. 2021; Zhou 2009). Therefore, starch content directly influences grain weight, which is a critical component of yield.
Proteolysis Targeting Chimera (PROTACs) in Cancer: From Molecular Mechanisms to Therapeutic Opportunities
Conflicts of Interest The authors declare no conflicts of interest. References 1, , , et al., “Targeting SOX13 Inhibits Assembly of Respiratory Chain Supercomplexes to Overcome Ferroptosis Resistance in Gastric Cancer,” Nature Communications 15 (2024): 4296. 2, , , et al., “Enhancing Panvascular Medicine: Unveiling the Nexus of Pan-Cardio-Oncology and Expanding Therapeutic Frontiers,” Science Bulletin 70 (2025): 798–800.
Influence of operating speed, load and mileage on the lubricating performance of self-lubricating rolling linear guide
Citation: Wu H, Lin N, Shen B, Liu L, Lu E, Xu G, et al. (2025) Influence of operating speed, load and mileage on the lubricating performance of self-lubricating rolling linear guide. PLoS One 20(7): e0328534. https://doi.org/10.1371/journal.pone.0328534 Editor: Antonio Riveiro Rodríguez, University of Vigo, SPAIN Received: February 11, 2025; Accepted: July 2, 2025; Published: July 21, 2025 Copyright: © 2025 Wu et al.
Ultrasound Phenotype, Genetic Analysis, and Pregnancy Outcomes of Fetuses With 1p36 Deletion Syndrome
1 Introduction A deletion in chromosome 1 at position 1p36, at the end of the short arm, is referred to as 1p36 deletion syndrome or 1p36 monomer syndrome. This is the most common chromosome deletion syndrome and has an incidence of approximately 0.1% in newborns and a detection rate of approximately 1% in patients with intellectual disability (Kang et al. 2016; Valerie et al. 2015).
Lycium barbarum Polysaccharide-Stabilized Selenium Nanoparticles Deliver Triptolide to Induce Apoptosis for Pancreatic Cancer In Vitro and In Vivo
1. Introduction Click to copy section linkSection link copied! Pancreatic cancer (PC) is a common digestive system tumor with the highest mortality rate. (1) Surgical resection is the most effective therapeutic method in clinical practice; however, the 5-year survival rate of PC is less than 5%. The lack of early diagnosis and high metastasis rate cause significant difficulties for surgical treatment, making the resection rate to be lower than 20%.
Müller-Lyer illusion in adults increases with age but is not affected
Bichi Chen,* Na Lin,* Li Tian, Jieli Mao, Maoyuan Yang, Xueqin Sun, Fan Lu, Ruzhi Deng National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, People’s Republic of China *These authors contributed equally to this work Correspondence: Ruzhi Deng, National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, People’s Republic of China, Email [email protected] Fan Lu, National Clinical...
Both Proteins/Peptides and Non‐Proteins/Peptides in Larval Oral Secretions of a Chewing Herbivore Function as Elicitors That Induce Plant Defenses
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description pce15523-sup-0001-SSB_OS_SI_0313R.docx1.9 MB SSB OS-SI-0313. References , , , , and . 2015. “Cues From Chewing Insects— the Intersection of DAMPs, HAMPs, MAMPs and Effectors.” Current Opinion in Plant Biology 26: 80–86. , , , et al. 2016. “Systematic Analysis of Rice (Oryza sativa) Metabolic Responses to Herbivory.” Plant, Cell & Environment 39: 453–466. , , , et al. 2007.
"Ectoine Enhances Mucin Production Via Restoring IL-13/IFN-γ Balance in" by Na Lin, Xin Chen et al.
PURPOSE: This study aimed to explore protective effects and potential mechanism of ectoine, a natural osmoprotectant, on ocular surface mucin production in dry eye disease. METHODS: A dry eye model was established in C57BL/6 mice exposed to desiccating stress (DS) with untreated (UT) mice as controls. DS mice were topically treated with 2.0% ectoine or PBS vehicle. Corneal epithelial defects were assessed by Oregon Green Dextran (OGD) fluorescent staining.
"Ectoine, from a Natural Bacteria Protectant to a New Treatment of Dry " by Xin Chen, Na Lin et al.
Keywords cornea, dry eye, ectoine, inflammation, murine model Abstract Ectoine, a novel natural osmoprotectant, protects bacteria living in extreme environments. This study aimed to explore the therapeutic effect of ectoine for dry eye disease. An experimental dry eye model was created in C57BL/6 mice exposed to desiccating stress (DS) with untreated mice as controls (UT). DS mice were dosed topically with 0.5-2.0% of ectoine or a vehicle control.
Patient‐Derived Bladder Cancer Organoids as a Valuable Tool for Understanding Tumor Biology and Developing Personalized Treatment
1 Introduction Bladder cancer includes two main disease conditions, non-muscle invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC). For patients with NMIBC, the standard treatment approaches include transurethral resection of bladder tumor (TURBT) operation, single-dose intravesical chemotherapy, and Bacillus Calmette-Guérin (BCG) treatment.
Comparison of Volatile and Non-Volatile Compounds of Ice-Stored Large Yellow Croaker (Larimichthys crocea) Affected by Different Post-Harvest Handling Methods
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
A Study on Device Physics of Deep Ultraviolet Light Emitting Diodes Leveraging Machine Learning
A Study on Device Physics of Deep Ultraviolet Light Emitting Diodes Leveraging Machine Learning Aluminum gallium nitride (AlGaN)-based deep ultraviolet (DUV) light-emitting diodes (LEDs) hold tremendous potential and application prospects. However, DUV LEDs face challenges such as low internal quantum efficiency (IQE) and degraded luminous performance because of properties intrinsic to aluminum-rich group III- nitride materials.
Zero-dimensional cuprous halide scintillator with ultra-high anti-water stability for X-ray imaging
Zero-dimensional cuprous halide scintillator with ultra-high anti-water stability for X-ray imaging† Zero-dimensional (0D) cuprous organic–inorganic hybrid halides have emerged as a new kind of scintillator due to their high light yield and adjustable emission properties in the whole visible spectral range. However, their practical application in the radiation industry is seriously hindered by the instability of CuI ions under humid atmospheres and oxidizing environments.
YOLO-Vehicle-Pro: A Cloud-Edge Collaborative Framework for Object Detection in Autonomous Driving under Adverse Weather Conditions
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Broadband Blue Light Emissions of One-Dimensional Hybrid Cu(I) Halides with Ultrahigh Anti-Water Stability
Broadband Blue Light Emissions of One-Dimensional Hybrid Cu(I) Halides with Ultrahigh Anti-Water Stability Low-dimensional organic-inorganic hybrid lead halide perovskites have attracted numerous interests in solid state lighting and displays, but the toxic and instability of lead halide are obstacles of industrial applications which must be overcame.
Identification and knockout of a herbivore susceptibility gene enhances planthopper resistance and increases rice yield - Nature Food
Abstract Brown planthoppers (Nilaparvata lugens) and white-backed planthoppers (Sogatella furcifera) are among the most destructive pests on rice. However, plant susceptibility genes have not yet been exploited for crop protection. Here we identified a leucine-rich repeat protein, OsLRR2, from susceptible rice varieties that facilitates infestation by brown planthopper N. lugens.
Circulating tumor DNA mutation analysis: advances in its application for early diagnosis of hepatocellular carcinoma and therapeutic efficacy monitoring | Aging
Review Volume 16, Issue 14 pp 11460—11474 1 Department of Clinical laboratory, Fourth People’s Hospital of Jinan, Jinan 250031, China https://doi.org/10.18632/aging.205980 How to Cite Cite this Article Select the format you require from the list below Click to copy this citation from the text box above or download the citation: Citation | This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use,...
Foods | Free Full-Text | Notch Signaling Inhibition Alleviates Allergies Caused by Antarctic Krill Tropomyosin through Improving Th1/Th2 Imbalance and Modulating Gut Microbiota
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Effects of Thinning on Carbon Storage in a Mixed Broadleaved Plantation in a Subtropical Area of China Original
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Characteristics and Conductivity of Emamectin Benzoate-Inclusive Nanocapsule in Pinus massoniana Lamb.
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
The prognosis, chemotherapy and immunotherapy efficacy of the SUMOylation pathway signature and the role of UBA2 in lung adenocarcinoma
Research Paper Volume 16, Issue 5 pp 4378—4395 1 Central Laboratory, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian 362000, China 2 Department of Pathology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian 362000, China 3 Jiangxi Health Commission Key Laboratory of Leukemia, The Affiliated Ganzhou Hospital of Nanchang University, Ganzhou, Jiangxi 341000, China 4 Laboratory Animal Center, The Second Affiliated Hospital of Fujian...
The prognosis, chemotherapy and immunotherapy efficacy of the SUMOylation pathway signature and the role of UBA2 in lung adenocarcinoma
Research Paper Volume 16, Issue 5 pp 4378—4395 1 Central Laboratory, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian 362000, China 2 Department of Pathology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian 362000, China 3 Jiangxi Health Commission Key Laboratory of Leukemia, The Affiliated Ganzhou Hospital of Nanchang University, Ganzhou, Jiangxi 341000, China 4 Laboratory Animal Center, The Second Affiliated Hospital of Fujian...
Ectoine, from a Natural Bacteria Protectant to a New Treatment of Dry Eye Disease
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Respiratory effects of pressure support ventilation in spontaneously breathing patients under anaesthesia: Randomised controlled trial
DATA AVAILABILITY STATEMENT The data that support the findings of this study are available from the corresponding author upon reasonable request.
Fetal mosaicism, should conventional karyotype always be performed?
The application of classical cytogenetic and DNA-based molecular techniques to detect cell lineages of mosaicism derived from cultured or noncultured fetal cells may result in discordant results. This retrospective study aimed to assess the inconsistent diagnostic outcomes, technical availability, and limitations of chromosomal microarray analysis (CMA) and karyotyping for mosaicism.
Urban Vegetation Extraction from High-Resolution Remote Sensing Imagery on SD-UNet and Vegetation Spectral Features
1. Introduction In urban areas, vegetation holds a crucial position within the urban ecosystem, assuming multifaceted and considerable important roles [1,2], including alleviating environmental pollution [3,4,5], protecting biodiversity [6,7], regulating the ecosystem [8], reducing the urban heat island effect [9,], and improving the overall quality of life [].
Regionalizing Nitrogen Doping of Polysilicon Films Enabling High‐Efficiency Tunnel Oxide Passivating Contact Silicon Solar Cells
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description smll202304348-sup-0001-SuppMat.pdf1.8 MB Supporting Information smll202304348-sup-0002-VideoS1.mp42.2 MB Supporting Information Video 1 smll202304348-sup-0003-VideoS2.mp42.3 MB Supporting Information Video 2 References 1, , , , , Nat. Energy 2019, 4, 914. 2, , , , , in 28th European PV solar energy conference and exhibition, Paris, France 2013. 3, , , , , Sol. Energy Mater. Sol.
0D Hybrid Cuprous Halide as an Efficient Light Emitter and X‐Ray Scintillator
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description lpor202300427-sup-0001-SuppMat.pdf1.8 MB Supporting Information References 1a) , , , , , , , , , , , , Adv. Funct. Mater. 2022, 33, 2210481; b) , , , , , , Angew. Chem., Int. Ed. 2022, 61, e202113450; c) , , , , Adv. Funct. Mater. 2022, 32, 2206459. 2a) , , , , , , Chem. Mater. 2020, 32, 1667; b) , , , , , , , , , , , , , , , , , , Adv. Mater.
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