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Nabeel Bardeesy on Muck Rack

Nabeel Bardeesy

As seen in: Nature, Wiley, MDPI, Science Magazine, Cell Press, Genes and Development Journal
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Articles

Inflammatory cytokines induce new cancer dependencies

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By Collins K. Cheruiyot, Sarah Kim, Juan Dubrot, Sarah K. Lane-Reticker, Alex Miranda Verified, Ashwin V. Kammula, Jonathan Perera, Peter Du, Cun Lan Chuong, Rachel Fetterman, Nelson H. Knudsen, Aiping Jiang, Lomax F. Pass, Cong Fu, Meng-Ju Wu, Seth Anderson, Audrey J. Muscato, Omar Ávila, Ian Kohnle, Emily A. Kessler, Hans W. Pope, Sarah Noel, Kira E. Olander, Jooho Chung, Kayla J Colvin, Nabeel Bardeesy, Kathleen B. Yates, Robert T. Manguso, Juliette S. M. T. Suermondt
| Nature Verified
Abstract Tumor cells respond and adapt to environmental stresses that facilitate growth in hostile environments, including cytokine-mediated inflammation elicited by antitumor immunity and enhanced by immune checkpoint blockade (ICB). However, cytokine responses also induce transcriptional and cell-state changes that may predispose tumor cells to new vulnerabilities, which remain poorly explored.
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Claudin-1 targeting suppresses tumor growth, invasion, and metastasis in patient-derived cholangiocarcinoma models

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By Zeina Nehme, Yosuke Sakamachi, Peina Wang, Marion Müller, Emilie Crouchet, Frank Jühling, Mélissa Messé, Julien Moehlin, Romain Désert, Fabio Del Zompo, Christine Thumann, Joachim Lupberger, Natascha Roehlen, Emanuele Felli, Patrick Pessaux, Aïna Venkatasamy, Patrice Marchand, Roberto Iacone, Markus Meyer Verified, Alberto Toso, Nabeel Bardeesy, Daniela Sia, Jade Brochon, Laura Meiss-Heydmann, Mihaela Alina Onea
| Science Magazine Verified
Editor’s summary Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Editor’s summary Cholangiocarcinoma (CCA) is an aggressive adenocarcinoma that arises from the bile ducts and has limited treatment options. To explore potential therapeutic targets, Nehme et al. investigated the role of claudin-1 (CLDN1), a transmembrane protein expressed in tight junctions, as an oncogenic driver in CCA.
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Author Correction: Discovery of chirally dependent protein modifications by D- and L-2-hydroxyglutarates

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By Zheng Zhang, Yi-Kai Liu, Zhuojun Luo, Meng-Ju Wu, Claudia N. Evans, Zihan Qu, Fanglei Xue, Zhijian Wang, Lia Stanciu, Zhong-Yin Zhang, Elizabeth I. Parkinson, Nabeel Bardeesy, W. Tao
| Nature Verified
Correction to: Nature Chemistry https://doi.org/10.1038/s41557-026-02093-x, published online 17 March 2026. In the version of this article initially published, there was an error in the spelling of Zhijian Wang’s first name (Zijian) which is now amended in the HTML and PDF versions of the article.
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