Nicholas D. Socci on Muck Rack

Nicholas D. Socci

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Articles

Clinicogenomic analysis of EGFR -mutant lung tumors identifies Rb pathway inactivation as a hallmark of squamous transformation

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By Melis N. Anahtar, Dimitra Karagkouni, Youssif M. Ali, Mark Jeng, Arielle Elkrief, Harshita Mehrotra, Soo-Ryum Yang, Christina Wilson, Natasha Rekhtman, Irina Linkov, Amanda Pupo, Christina J. Falcon, Clare Wilhelm, Parvathy Manoj, Hong Zhong, Harsha Sridhar, Mark G. Kris, Nicholas D. Socci, Juan Qiu, Elisa de Stanchina, Allison Richards, Charles M. Rudin, Helena A. Yu, Alexandria Dymun, Mark T. A. Donoghue
| Science Magazine Verified
Editor’s summary Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Editor’s summary Non–small cell lung cancer (NSCLC) can develop resistance to targeted therapy by transforming into small cell lung cancer (SCLC) or lung squamous cell carcinoma (LUSC). Here, Dymun et al.
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Role of clonal inflammatory microglia in histiocytosis-associated neurodegeneration

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By Rocio Vicario, Stamatina Fragkogianni, Maria Pokrovskii, Carina Meyer, Estibaliz Lopez-Rodrigo, Yang Hu, Masato Ogishi, Araitz Alberdi, Ann Baako, Oyku Ay, Isabelle Plu, Véronique Sazdovitch, Sébastien Heritier, Fleur Cohen-Aubart, Natalia Shor, Makoto Miyara, Florence Nguyen-Khac, Agnes Viale, Ahmed Idbaih, Zahir Amoura, Marc K. Rosenblum, Haochen Zhang, Elias-Ramzey Karnoub, Palash Sashittal, Akhil Jakatdar, Christine A. Iacobuzio-Donahue, Omar Abdel-Wahab Verified, Viviane Tabar, Nicholas D. Socci, Olivier Elemento, Eli L. Diamond, Bertrand Boisson, Jean-Laurent Casanova Verified, Danielle Seilhean, Julien Haroche, Jean Donadieu, Frederic Geissmann
| Cell Press Verified
Keywords Neurodegeneration MAPK pathway microglia hippocampus brainstem resident macrophages Introduction Langerhans cell histiocytosis (LCH)1 and Erdheim-Chester disease (ECD)2,3 are rare clonal myeloid disorders, with an estimated incidence of ∼5 cases per million people per year.4 They are sometimes co-diagnosed in the same patients,5 and both associated with a high prevalence of the BRAFV600E mutation1,2,3,6,7,8 as well as an increased risk of neurodegenerative disease...
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By Jing Pan Verified, Seoyoung C. Kim, Xuan Zhu, Nicholas D. Socci, Maria Jasin, Scott Keeney, Julian Lange, Shintaro Yamada, Sam E. Tischfield
| secure.jbs.elsevierhealth.com
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