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Jean-Laurent Casanova on Muck Rack

Jean-Laurent Casanova

Verified
New York
As seen in: Journal of Clinical Immunology, Nature, Wiley Online Library, PNAS, The Conversation, Science Magazine, The New England Journal of Medicine, BioRxiv, Cell Press, The American Journal of Human Genetics, Mary Ann Liebert, Inc. and
We're a research lab at UT Southwestern (Texas) and Necker Hospital (Paris) studying human genetic and immunological determinants of infectious diseases.
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Articles

Pyoderma gangrenosum caused by the molecular uncoupling of OTULIN catalytic activity and LUBAC binding

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By Barathram Swaminathan, Hwi M. Gil, Sagar Bhattad, Jyothi Janardhanan, Gerardo Baltodano, Christine Mariskanish, Shamel Basaria, Joseph Choi Verified, Qi Liu, Lisette M. Scheepmaker, Mohamud Awil Mohamed, Bertrand Boisson, Jean-Laurent Casanova Verified, Ivona Aksentijevich, András N. Spaan, Janet G. Markle
| Nature Verified
Abstract The pathogenic mechanisms underlying pyoderma gangrenosum (PG) remain unclear. Here we report three patients with PG from two unrelated kindreds with homozygous R57C mutation of the linear deubiquitinase OTULIN. The patients have isolated, pediatric-onset, OTULIN-related PG (ORP).
Open in Who Shared Issue with article?

Autoantibodies against Cytokines — From Infection to Inflammation

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By Jean-Laurent Casanova Verified
| nej.md
Are you a member of an institution such as a university or hospital?Learn more about Institutional Access Notes Disclosure forms provided by the authors are available with the full text of this editorial at NEJM.org. Supplementary Material Disclosure Forms (nejme2603635_disclosures.pdf)
Open in Who Shared View Duplicates (2) Issue with article?

Autoantibodies against Cytokines — From Infection to Inflammation

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By Jean-Laurent Casanova Verified
| The New England Journal of Medicine Verified
Are you a member of an institution such as a university or hospital?Learn more about Institutional Access Notes Disclosure forms provided by the authors are available with the full text of this editorial at NEJM.org. Supplementary Material Disclosure Forms (nejme2603635_disclosures.pdf)
Open in Who Shared View Duplicates (3) Issue with article?
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