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Ning Xin

As seen in: Nature, Wiley Online Library, Voice of America (VOA), Science Magazine
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Articles by Ning Xin

An adaptive autoregressive integration model for multi-variate time series analysis of extreme climate events

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By Ning Xin, Jionglong Su, Maruf Hasan
| Nature Verified
Abstract Summer droughts are becoming increasingly severe under climate change, posing significant threats to global food security and ecosystem stability. While multivariate time series (MTS) analysis has emerged as a powerful tool for environmental modeling, it suffers from two limitations: (1) failure to account for temporal volatility patterns, and (2) difficulty in capturing non-stationary relationships among meteorological variables.
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Epithelial plasticity shapes intratumoral heterogeneity and cell lineages in early-stage lung cancer

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By Yu Xiao, Yatian Chen, Yoshihiro Okamura, Xiaofang Wang, Kai Yan, Ning Xin, Weiqing Li, Zhengwei Zhang, Chunling Zeng, Yuxiang Luo, Xiaoxiao Liu, Xiaojing Lu, Yue Dong, Xu Lin, Ying Li, Xiaona Jia, Simin Wang, Hua Tang, Yuexiang Wang, Yangjie Xiong, Yumei Cheng, Xinhui Yan, Haoqi Lan, Tanwen Wu
| Science Magazine Verified
Abstract Intratumoral heterogeneity (ITH) has been investigated primarily in locally advanced or metastatic cancer; however, much less is known about ITH in early-stage cancer, and the origins of ITH are poorly understood. Through single-cell and spatial transcriptomics of early-stage ground-glass opacity (GGO)–like lung adenocarcinoma (LUAD) (14 patients; 103,375 cells), we systematically define tumor states and demonstrate that pervasive transcriptional ITH exists in early-stage LUAD.
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Long‐Term Minocycline Treatment Exhibits Enhanced Therapeutic Effects on Ischemic Stroke by Suppressing Inflammatory Phenotype of Microglia Through the EMB/MCT4/STING Pathway

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By Shangqi Liu, Ling Gao, Ning Xin, Zhenying Shang
| Wiley Online Library Verified
1 Introduction Stroke is the second leading cause of adult mortality worldwide, with ischemic stroke accounting for approximately 84% of all strokes [1]. Excessive activation of microglia after stroke exacerbates neuroinflammatory damage [1, 2]. Current treatments for ischemic stroke mainly rely on thrombolysis with drugs such as rt-PA and physical thrombectomy [3, 4], with limited options to alleviate poststroke neuroinflammatory damage, significantly affecting patient prognosis [5].
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China May Resurrect Title of ‘Chairman,’ Unused Since Mao’s Death

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By Ning Xin
| Voice of America (VOA) Verified
There is but one chairman in China, and that is Chairman Mao Zedong. He served as chairman of the central committee of the Communist Party of China, a position so absolutely powerful that party leaders retired it within years of his death in 1976. But is the title truly retired? Maybe not, given hints this summer that President Xi Jinping may be angling to resurrect it.
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