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Per Ludvik Brattås on Muck Rack

Per Ludvik Brattås

As seen in: Nature, The Conversation, Rappler, Cell Press, Cell Stem Cell, Singularity Hub, RealClear Science, Science X
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Articles

A cis-acting structural variation at the ZNF558 locus controls a gene regulatory network in human brain development

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By Pia Johansson, Per Ludvik Brattås, Christopher Douse
| Cell Stem Cell Verified
Highlights • ZNF558 is uniquely expressed in human but not chimpanzee forebrain progenitors • ZNF558 has been co-opted to control the expression of a single gene, SPATA18 • ZNF558 plays a role in mitochondrial homeostasis and brain development • ZNF558 expression is controlled by the size of a downstream VNTR Summary The human forebrain has expanded in size and complexity compared to chimpanzees despite limited changes in protein-coding genes, suggesting that gene expression regulation is an...
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Lab-Grown 'Mini Brains' Suggest One Mutation Might Have Rewired the Human Mind

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By Itzia Ferrer, Per Ludvik Brattås
| Singularity Hub Verified
How we humans became what we are today is a question that scientists have been trying to answer for a long time. How did we evolve such advanced cognitive abilities, giving rise to complex language, poetry, and rocket science? In what way is the modern human brain different from those of our closest evolutionary relatives, such as Neanderthals and Denisovans?
Open in Who Shared Issue with article?

Lab-grown 'mini brains' suggest one mutation might have rewired the human mind

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By Itzia Ferrer, Per Ludvik Brattås
| Science X Verified
How we humans became what we are today is a question that scientists have been trying to answer for a long time. How did we evolve such advanced cognitive abilities, giving rise to complex language, poetry and rocket science? In what way is the modern human brain different from those of our closest evolutionary relatives, such as Neanderthals and Denisovans?
Open in Who Shared Issue with article?
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