In recent years, the rise of the “online-informed” patient has transformed visits to dermatology practices, with clinicians increasingly encountering patients who greet them armed with TikTok skincare advice, Reddit-informed treatment data, AI-generated differential diagnoses, and screenshots from ChatGPT inquiries. In this feature, interviews between 4 leaders in dermatology and HCPLive highlight this trend as being simultaneously empowering to patients and potentially hazardous.