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Articles by Peter Lio
Q&A: Precision Medicine's Next Steps in Atopic Dermatitis, With Peter Lio, MD
Atopic dermatitis treatment continues to expand beyond injectable biologics, even as clinicians still lack tools to match patients with the right therapy up front. Response rates with current interleukin (IL)-4 and IL-13 blockade remain good but not complete, leaving a meaningful share of patients under-treated despite an increasingly crowded pipeline.
Q&A: SKiN Angels and AI's Growing Role in Dermatology, With Peter Lio, MD
Published on: Peter Lio, MD, discusses SKiN Angels dermatology investing and AI's growing role in patient care and clinician education. Artificial intelligence (AI) is moving quickly from novelty to clinical tool in dermatology.
The Present and Future of Precision Medicine in Dermatology, With Peter Lio, MD
Precision medicine in dermatology continues to evolve through incremental refinement rather than a single defining breakthrough, according to Peter Lio, MD, speaking at the 2026 LEADderm conference following his sessions.1,2 Lio, clinical assistant professor of dermatology and pediatrics at Northwestern University Feinberg School of Medicine and founding director of the Chicago Integrative Eczema Center, described the process as a virtuous cycle in which new medicines deepen understanding of...
Dermatologists Comment on the 2026 American Academy of Dermatology Pediatric Atopic Dermatitis Guidelines
In April, the first American Academy of Dermatology (AAD) guidelines for pediatric atopic dermatitis (AD) were released in two separate publications in the Journal of the American Academy of Dermatology. One focuses on the management of AD with topical and systemic treatments, and phototherapy, and 27 evidence-based recommendations with "strong" or "conditional" recommendations based on the certainty of evidence.
Skin Angels and the Atopic Dermatitis Pipeline, With Peter Lio, MD
At LEADderm 2026, held August 29-30 in Newport Beach, California, Peter Lio, MD, clinical assistant professor of dermatology and pediatrics at Northwestern University Feinberg School of Medicine and founding director of the Chicago Integrative Eczema Center, previewed his session introducing Skin Angels, the Strategic Knowledge and Investment Network Group.
Illuminating Connections: Exploring the Dynamic Relationship Between Phototherapy and the Skin
AD atopic dermatitis AMP antimicrobial peptide BLP blue light phototherapy LED light-emitting diode SINGE skin-immune-neuro-gastro-endocrine TEWL transepidermal water loss TLR toll-like receptors 1 Introduction The neonatal period represents a critical window of rapid adaptation. As the newborn transitions from the sterile, aqueous environment of the uterus, it encounters the dry, microbe-rich outside world.
Association Between Household Endotoxin Exposure and Atopic Dermatitis: A Cross-Sectional U.S.-Based Population Study
Keywords allergy atopic dermatitis eczema endotoxins skin microbiome Abbreviations AD (atopic dermatitis) NCHS (National Center for Health Statistics) NHANES (National Health and Nutrition Examination Survey) NHW (Non-Hispanic White) Th (T helper type) Get full text access Log in, subscribe or purchase for full access. References 1. Akdis, C.A. Does the epithelial barrier hypothesis explain the increase in allergy, autoimmunity and other chronic conditions? Nat Rev Immunol.
Discussing Current Treatment Options for Atopic Dermatitis, With Peter Lio, MD
This segment of Lio's RAD Conference interview in Nashville highlights the growing number of therapeutics and an increasingly personalized approach.
Upcoming AAD Pediatric Guidelines and Tips for Kids in Dermatology, With Peter Lio, MD
HCPLive’s editorial team spoke on-site with Peter Lio, MD, clinical assistant professor of dermatology and pediatrics at Northwestern University Feinberg School of Medicine, following his session presented at the Revolutionizing Atopic Dermatitis (RAD) Conference 2026 in Nashville.
Wearable technology saves lives through early detection
I am a 94-year-old physician who would like to share a recent experience in which my Apple Watch played a critical role in the detection of a life-threatening event. Over the course of my career, I focused on early detection and prevention in medicine, particularly in colorectal cancer. This made my recent personal experience with early detection of a cardiac event and prevention of its serious consequences through wearable technology especially meaningful.
How Online-Informed Patients Are Changing Dermatology Visits
In recent years, the rise of the “online-informed” patient has transformed visits to dermatology practices, with clinicians increasingly encountering patients who greet them armed with TikTok skincare advice, Reddit-informed treatment data, AI-generated differential diagnoses, and screenshots from ChatGPT inquiries. In this feature, interviews between 4 leaders in dermatology and HCPLive highlight this trend as being simultaneously empowering to patients and potentially hazardous.
Medical relevance and evolution: Why physicians must reinvent themselves
Medicine is a field defined by constant evolution. Advances in technology, groundbreaking research, and shifting patient expectations continually reshape the landscape of health care. As physicians, we are entrusted with providing excellent care. But we must also ensure that our knowledge, skills, and approaches remain at the forefront of this ever-changing environment.
Inpatient Psychiatric Burden in Adolescents With Atopic Dermatitis
Conflicts of Interest P.A.L. reports being on the speaker's bureau for AbbVie, Arcutis, Eli Lilly, Galderma, Hyphens Pharma, Incyte, La Roche-Posay/L'Oreal, Pfizer, Pierre-Fabre Dermatologie, Regeneron/Sanofi Genzyme, Verrica; reports consulting/advisory boards for Alphyn Biologics, AbbVie, Almirall, Amyris, Apogee, Arcutis, ASLAN, Astria Therapeutics, Boston Skin Science, Bristol-Myers Squibb, Burt's Bees, Castle Biosciences, Codex Labs, Concerto Biosci, Dermavant, Eli Lilly, Galderma,...
The Inpatient Burden of Pediatric Dermatology in the United States: A National Analysis of the 2022 Kids' Inpatient Database
1 Introduction Inpatient care represents a substantial proportion of U.S. healthcare expenditures, and dermatologic conditions continue to account for a meaningful share of pediatric hospitalizations [1, 2]. Although most pediatric skin diseases are managed in the outpatient setting, certain infections, congenital disorders, and inflammatory conditions require inpatient admission and generate significant costs [3].
VIDEO: ‘An abundance of therapies’ are currently available for atopic dermatitis
Editor’s note: This is an automatically generated transcript. Please notify editor@healio.com if there are concerns regarding accuracy of the transcription. Hi, I'm Dr. Peter Lio. I'm a clinical assistant professor of dermatology at Northwestern University Feinberg School of Medicine in Chicago, Illinois. It has been an incredible time for atopic dermatitis therapies.
VIDEO: Managing comorbidities in atopic dermatitis
Editor’s note: This is an automatically generated transcript. Please notify editor@healio.com if there are concerns regarding accuracy of the transcription. There are a lot of comorbidities for atopic dermatitis and that makes it particularly challenging, right? It's not just a skin problem and it's super insulting, right? When people outside of dermatology, of course, because we know, but people outside will say, "Oh, it's just a skin thing, it's just a rash. Why do you care?" Why do we care?
VIDEO: Preventing flares is ‘the goal’ in atopic dermatitis
Editor’s note: This is an automatically generated transcript. Please notify editor@healio.com if there are concerns regarding accuracy of the transcription. We feel very strongly that our goal is not to treat flares. Obviously, we will do that if someone's in a flare, and we want to empower people to be able to do that, but exactly right. The goal is that we want to prevent them in the first place.
VIDEO: Various biologic, topical treatments being studied for atopic dermatitis
Editor’s note: This is an automatically generated transcript. Please notify editor@healio.com if there are concerns regarding accuracy of the transcription. There are a lot of things that are in the pipeline now. Last time I counted, it was over 100 different treatments are actually actively being studied. So, I'm officially, and even as an eczema nerd, I'm officially overwhelmed trying to follow all these different paths. But that being said, this is a wonderful problem to have.
Urbanization, Lifestyle, and Skin Barrier Damage in Atopic Dermatitis
Videos Dr Peter Lio discusses how urbanization, modern lifestyles, and shifting environmental exposures may be driving rising rates of allergic rhinitis, food allergy, and atopic dermatitis—and which exposures should most concern clinicians. Peter Lio, MD is a Clinical Assistant Professor of Dermatology & Pediatrics at Northwestern University Feinberg School of Medicine.
Chemical Exposures, Pollen Flares & the Microbiome in Atopic Dermatitis
Videos Learn how household chemicals, airborne pollutants, and seasonal pollen surges drive atopic dermatitis flares. Dr Peter Lio examines environmental triggers and microbiome disruption in AD for allergists and immunologists. Peter Lio, MD is a Clinical Assistant Professor of Dermatology & Pediatrics at Northwestern University Feinberg School of Medicine.
Barrier Support & Environmental Interventions in Atopic Disease
Videos Dr Peter Lio reviews the role of barrier-support strategies, environmental interventions like air and water modifiers, and emerging research and therapies for environmentally driven atopic disease, with practical takeaways for allergists and immunologists. Peter Lio, MD is a Clinical Assistant Professor of Dermatology & Pediatrics at Northwestern University Feinberg School of Medicine.
Environmental Triggers of Atopic Dermatitis & Seasonal Allergies
Videos In this interview, Peter Lio, MD, explores how modern environmental exposures—from pollution to lifestyle shifts—are accelerating type 2 inflammation and fueling atopic dermatitis and seasonal allergies in today’s patients. Peter Lio, MD is a Clinical Assistant Professor of Dermatology & Pediatrics at Northwestern University Feinberg School of Medicine.
Topical Steroid Withdrawal: Inside the Controversy Over TSW in Dermatology
Topical steroid withdrawal (TSW) is a controversial topic in the field of dermatology, precisely because it exposes the fault lines between patient experience and clinical consensus. Long discussed in patient communities found online, a wider acknowledgement of TSW has largely remained unseen. TSW is often a contested diagnosis, recognized by some dermatologists as a distinct entity but dismissed by others as simply a severe or undertreated atopic dermatitis flare.
Discussing New Topical Drugs for Atopic Dermatitis in Younger Patients, With Peter Lio, MD
An interview was conducted at the 2025 Fall Clinical Dermatology Conference in Las Vegas, featuring Peter A. Lio, MD, a clinical professor of Dermatology at the Icahn School of Medicine at Mount Sinai and clinical assistant professor of Dermatology & Pediatrics at Northwestern University’s Feinberg School of Medicine.
The Critical Value of Remission in Dermatologic Care
In the evolving world of dermatologic care, the goal of treatment is no longer simply to manage symptoms or slow disease progression. For several conditions, achieving remission is now a realizable goal. If prevention would be the best of all goals, curing a disease second best, then remission — in any of its forms — would not be far behind.
How to Approach Integrative Medicine
Skip to main content Contact Sign in Clinical Pearls Integrative medicine bridges conventional treatments with complementary approaches, offering a holistic, patient-centered strategy for dermatologic care. By combining evidence-based therapies with practical, safe, and innovative methods, clinicians can address unique patient needs while fostering hope and balanced healing.
Complementary and Alternative Approaches to Skin Cancer
Introduction Complementary and alternative medicine (CAM) has gained increasing attention within dermatology and oncology as patients seek holistic and less invasive approaches to managing skin cancers. From 2016-2018 some 6.1 million American adults were treated for skin cancer, which resulted in $8.9 billion in cumulative treatment costs.1 The high prevalence of skin cancer and associated medical expenditures incentivize many patients to explore alternative therapies.
Response to: Pediatric Topical Steroid Withdrawal Syndrome: What Is Known, What Is Unknown
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Why holding a patient’s hand matters more than technology
I was on another overnight shift in the OB/GYN emergency department. The air was thick with tension, as it always is when the night is full of contractions, cries, and codes. One woman arrived in active labor — her first baby, frightened eyes, and no family by her side. Everyone rushed to prepare for the delivery. Monitors beeped. Gloves snapped. Orders flew around the room. The focus was on the baby. Get the fetal heart tones. Check cervical dilation. Prepare the warmer. But no one looked her in the eyes.
Mastering medical presentations: Elevating your impact
As health care professionals, we are constantly immersed in data, intricate details, and complex ideas. Whether presenting at grand rounds, sharing research at conferences, or explaining treatment plans to patients, your PowerPoint slides can either amplify your message or obscure it in a deluge of information. Let’s be clear: Effective communication is not merely a desirable trait; it is a clinical necessity.
Addressing Doubts About Topical Steroid Withdrawal (TSW), with Peter Lio, MD
In another segment of his HCPLive interview at the 2025 Revolutionizing Atopic Dermatitis (RAD) Conference, Peter Lio, MD, spoke about topical steroid withdrawal at the atopic dermatitis-focused meeting. Lio, who works at Northwestern University's Feinberg School of Medicine as a clinical assistant professor of dermatology and pediatrics, touched on the topic following his shared session about topical steroid withdrawal and its relationship to atopic dermatitis.
Precision Medicine in Today’s Atopic Dermatitis Landscape, with Peter Lio, MD
Peter Lio, MD, provided an on-site interview with the HCPLive editorial team during the 2025 Revolutionizing Atopic Dermatitis (RAD) Conference in Nashville, and in this segment he spoke about the prospect of personalized medicine as well as other takeaways from one of his sessions on pediatric atopic dermatitis. Lio serves as a clinical assistant professor of dermatology and pediatrics at Northwestern University's Feinberg School of Medicine.
Tips for Communicating with Caregivers for Pediatric Atopic Dermatitis, with Peter Lio, MD
In a new interview at the 2025 Revolutionizing Atopic Dermatitis (RAD) Conference in Nashville, Peter Lio, MD, spoke about some of the most notable takeaways from his talk titled ‘Pediatric AD: Patient, Provider, Caregiver Connection.’ Lio—known for his role as a clinical assistant professor of dermatology and pediatrics at Northwestern University's Feinberg School of Medicine—focused on the complex dynamics of care in pediatric dermatology, emphasizing the role of caregivers in addition to...
Previewing Revolutionizing Atopic Dermatitis 2025, with Peter Lio, MD
As the field of dermatology continues to evolve at a rapid pace, the Revolutionizing Atopic Dermatitis (RAD) Annual Meeting remains a cornerstone for education, collaboration, and progress in patient care. Atopic dermatitis has seen an explosion in interest and therapeutic advancement in recent years. There are more options than ever but figuring out how to use them in real life with real patients has made clinician education on the topic more important than ever.
VIDEO: AAD research indicates dermatologists are in ‘the decade of atopic dermatitis’
Source: Healio interviews Disclosures: Lio reports having financial relationships with AbbVie, Almirall, Altus Labs, Amyris, AOBiome, Arbonne, ASLAN Pharmaceuticals, Bodewell, Burt’s Bees, Castle Biosciences, Dermavant, Eli Lilly, Exeltis, Galderma, IntraDerm, Johnson & Johnson, Kimberly Clark, KP Away, L’Oreal, LearnSkin, LEO Pharma, Level Ex, Menlo Therapeutics, Micreos, My-OR Diagnostics, Pfizer, Pierre-Fabre, Regeneron/Sanofi Genzyme, Theraplex, Unilever, Verrica and Yobee Care.
VIDEO: State of the pipeline, drug updates in atopic dermatitis
In this video, Peter Lio, MD, discussed updates on topical agents, biologics and drugs in the pipeline in atopic dermatitis from presentations at the American Academy of Dermatology meeting. Lio highlighted the four AD biologics: dupilumab, lebrikizumab, tralokinumab and nemolizumab, each of which had new data presented at the meeting. He also highlighted upadacitinib and abrocitinib, the oral Janus kinase inhibitors for AD.
An Updated Scoping Review of Disparities in Pediatric Atopic Dermatitis
1 Introduction Health disparities are preventable differences in aspects of health experienced by marginalized patient populations [1]. These disparities can be seen across demographics, income levels, and regions. Addressing health disparities is essential to ensure equitable care for all patients.
Diet represents ‘one piece of the puzzle’ in managing atopic dermatitis
Key takeaways: Clinicians should discuss the role of diet with patients looking for nutritional solutions for atopic dermatitis. While certain diets can be harmful, evidence suggests anti-inflammatory diets are beneficial. ORLANDO — Nutrition plays a role in the management of atopic dermatitis, according to research presented at the American Academy of Dermatology Annual Meeting.
‘Will make life better’: FDA advances Zoryve cream 0.05% for pediatric atopic dermatitis
Key takeaways: If approved, this topical will offer a nonsteroidal option for caregivers and their children with atopic dermatitis. The FDA has set a target action date of Oct. 13. Editor’s note: This is a developing news story. Please check back soon for updates. The FDA has accepted the supplemental new drug application for Zoryve cream 0.05% to treat mild to moderate atopic dermatitis in children aged 2 to 5 years, according to a press release from the manufacturer.
Environmental Impact on Atopy
Skip to main content Contact Sign in Clinical Pearls Dr Peter Lio explores the link between environmental factors, such as pollution and lifestyle changes, and the rise of atopic dermatitis and type 2 inflammation. He emphasizes the importance of barrier protection, skin microbiome health, and effective moisturization in managing and preventing these conditions.
VIDEO: Environmental changes may be to blame for rise of atopy, atopic dermatitis
MIAMI BEACH, Fla. — The production of isocyanate compounds from the environment may explain the increasing prevalence of atopic dermatitis, according to a speaker at Masters of Pediatric Dermatology. “We understand that the rate of allergies in general, but in particular atopic dermatitis, has gone up and up and up over the past few decades — far outpacing any kind of a specific genetic explanation,” Peter A.
VIDEO: Understanding topical steroid withdrawal syndrome important for treating patients
MIAMI BEACH, Fla. — Topical steroid withdrawal syndrome may signal a reminder to clinicians to be good stewards of topical treatments, according to a speaker at Masters of Pediatric Dermatology. “This is really important because it is a controversial entity,” Peter A. Lio, MD, clinical assistant professor of dermatology and pediatrics at Northwestern University Feinberg School of Medicine, told Healio in an interview about his presentation.
a program coordinator's guide [PODCAST]
Subscribe to The Podcast by KevinMD. Watch on YouTube. Catch up on old episodes! A dermatology program coordinator, Christina Iwanik, discusses the KevinMD article, “Ways that one can succeed in dermatology residency: words of wisdom from a program coordinator.” She explores the importance of efficiently managing administrative tasks, staying proactive with surgical logs, and seeking supportive mentorship throughout residency.
Treatment of Topical Steroid Withdrawal Syndrome with Traditional Chinese Medicine: A Case Series of 5 Adults
Introduction Topical corticosteroids (TCS) play a major role in the management of inflammatory skin diseases such as atopic dermatitis, allergic contact dermatitis, and psoriasis.1 While they are generally considered safe and effective, topical steroid withdrawal syndrome (TSW) can emerge after patients stop the use of topical steroids or even with concomitant use.2 Patients can present with burning, stinging, painful skin; oozing, purulent rashes; confluent or general redness sometimes in a...
Why dermatology deserves respect: a medical student’s perspective
As a medical student pursuing dermatology, I was disheartened at the recent Wall Street Journal article’s misrepresentation of dermatology. Describing the field as a superficial, cosmetically focused pseudo-science is a disservice to both dermatologists and the patients they treat; representations such as this one erase the true scope of dermatologic care. Based on the patients I’ve seen so far, dermatology and its physicians deserve more respect.
Ways that one can succeed in dermatology residency: words of wisdom from a program coordinator
With sixteen years of experience working with dermatology residents, my role as a program coordinator has evolved immensely. Within the auspices of graduate medical education (GME), I manage the dermatology residency program, projects, and program budgets, assist in determining policies and procedures, and work closely with the program director with any and all directives given.
Pediatric Topical Steroid Withdrawal Syndrome: What Is Known, What Is Unknown
1 Introduction Topical steroid withdrawal syndrome (TSW) is a controversial condition characterized by erythema, burning, and/or itching generally seen after discontinuation of chronically used mid-to-high potency (typically class III and above) topical corticosteroids (TCS) [1-4]. TSW has colloquially been known as red skin syndrome and “elephant skin” [1-4].
Treatment Breaks and Rescue Treatments in Atopic Dermatitis
Advances in Oral Systemic Treatments for Management of Atopic Dermatitis - Episode 11 Published on: , , , Medical experts discuss how often patients with atopic dermatitis request treatment breaks, their monitoring approach during these breaks, and how to educate and counsel patients about treatment breaks and rescue treatments, including identifying suitable candidates.
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