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Rushil Chakrabarty on Muck Rack

Rushil Chakrabarty

As seen in: Nature, Cell Press, Cell Reports
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Articles

Technical and biological sources of noise confound multiplexed enhancer AAV screening

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By Avery C. Hunker, John K. Mich, Naz Taskin, Amy Torkelson, Trangthanh Cardenas, Jean-Benoît Lalanne, Joseph Mahoney, Darren Bertagnolli, Anish Bhaswanth Chakka, Rushil Chakrabarty, Nicholas Donadio, Rebecca A Ferrer, Molly J Gasperini, Jeff Goldy, Junitta B. Guzman, Kelly Jin, Shannon Khem, Rana Kutsal, Refugio Martinez, Dakota Newman, Nick Pena, Christine Rimorin, Dana Rocha, Nadiya Shapovalova, Michael Tieu, Natalie Weed, Thomas Zhou, Rebecca A Hodge, Shenqin Yao, Jay Shendure, Kimberly Smith, Ed Lein, Bosiljka Tasic, Boaz P. Levi, Jonathan T. Ting
| Nature Verified
Abstract Cis-acting regulatory enhancer elements are powerful tools for achieving cell type-specific genetic access in adeno-associated virus (AAV) delivery platforms. However, a significant bottleneck in enhancer discovery remains the accurate characterization of their in vivo expression patterns, which currently relies on labor-intensive, gold-standard one-by-one validation.
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Continuous cell-type diversification in mouse visual cortex development - Nature

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By Emma Thomas, Angela Ayala, Jazmin Campos, Rushil Chakrabarty, Michael Clark, Nathan Guilford, Zoe Juneau, Rachel McCue, thuc Nguyen, Paul Olsen, Jacob Quon, Augustin Ruiz, Amy Torkelson, Justin Wang, Jack Waters, Michael Kunst, Boaz P. Levi, Michael J. Hawrylycz, Chelsea Pagan, Kimberly Smith Verified, Bosiljka Tasic, Zizhen Yao
| Nature Verified
Abstract The mammalian cortex is composed of a highly diverse set of cell types and develops through a series of temporally regulated events1,2,3. Single-cell transcriptomics enables a systematic study of cell types across the entire timeline of cortical development. Here we present a comprehensive and high-resolution transcriptomic and epigenomic cell-type atlas of the developing mouse visual cortex.
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Transcriptomic and spatial organization of telencephalic GABAergic neurons - Nature

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By Michael Kunst, Delissa McMillen, Michael Clark, Rushil Chakrabarty, Scott Daniel, Emma Thomas, Amy Torkelson, Chelsea Pagan, Lauren Kruse, Jack Waters, Kimberly Smith Verified, Bosiljka Tasic, Zizhen Yao, Trangthanh Cardenas
| Nature Verified
Abstract The telencephalon of the mammalian brain contains multiple regions and circuits that have adaptive and integrative roles in a variety of brain functions. GABAergic neurons in the telencephalon are diverse; they have many circuit functions, and dysfunction of these neurons has been implicated in various brain disorders1,2,3.
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