Scott Boyd
Stanford
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Articles by Scott Boyd
Human lung organoid modelling of tissue-resident antiviral T cell responses
Abstract Tissue-resident immunity constitutes a first line of defence against pathogens and enables rapid innate and adaptive memory responses1,2,3. However, experimental studies have been hindered by a lack of holistic human in vitro models that enable epithelial infection in the context of tissue-resident immune subsets.
Immunoglobulin heavy chain locus duplication in bats
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Bats are major reservoirs of viruses that can be transmitted to humans in zoonotic outbreaks. Antibody-mediated immunity plays an important role in shaping viral evolution and immune evasion but remains understudied in bats.
Multiplexed antigen panel analysis identifies B cell phenotype and receptor genetic contributions to antibody breadth
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Keywords SARS-CoV-2 B cell mRNA vaccination infection COVID-19 antibody B cell receptor antigen-specific B cell atypical B cell viral variants single-cell transcriptome Introduction The appearance and global spread of SARS-CoV-2 (CoV-2) and its variants selected for their immune evasiveness has been well-documented.1,2,3 The spread of a novel virus in initially immunologically naive hosts provided a unique opportunity to study the formation of new B cell and T cell memory pools.4,5,6 The...
By Oliver Wirz, Prasanti Kotagiri, Emily Haraguchi, Katharina Röltgen, Molly Hunter, Erin Craig, Jumana Afaghani, Ji-Yeun Lee, Sandra C.A. Nielsen, Ramona A. Hoh, Taylor Pursell, Prabhu S Arunachalam, Monali Manohar, Iris Chang, Jackson Schuetz, Brandon Lam, Andréa Fernandes, Donna Smith, Brian Ha, Linda M. Liao, Javaria Najeeb, Chandler C. Ho, George B. Sigal, Theodore S. Jardetzky, Stuart Scott, Mark Davis, Benjamin A. Pinsky, Kari C. Nadeau, Fan Yang, Scott Boyd, Evan Do, Ana R. Otrelo-Cardoso, Jacob N. Wohlstadter, Sean Van Slyck, Jeremy Minshull, Claus U. Niemann
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Cell Press
Verified
Multi-omics reveal vitamin D regulation of immune-gut microbiome interactions and tolerogenic pathways in inflammatory bowel disease
Forty-eight patients with IBD completed the clinical trial and provided a full set of pre- and post-vitamin D treatment blood and stool samples (study schematic summarized in Figure 1A) and are included in the final analysis. Table 1 summarizes the baseline clinical characteristics of patients in the clinical trial. The mean age of patients was 38.96 years, and 45.8% were male and 54.2% were female. About 56.3% of patients had ulcerative colitis (UC), whereas 43.7% had Crohn disease (CD).
Turning a single-family into a multi family in Seattle Wa
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Mouse lemur cell atlas informs primate genes, physiology and disease - Nature
Abstract Mouse lemurs (Microcebus spp.) are an emerging primate model organism, but their genetics, cellular and molecular biology remain largely unexplored. In an accompanying paper1, we performed large-scale single-cell RNA sequencing of 27 organs from mouse lemurs. We identified more than 750 molecular cell types, characterized their transcriptomic profiles and provided insight into primate evolution of cell types.
Antibiotic-induced gut microbiome perturbation alters the immune responses to the rabies vaccine
Keywords systems biology systems vaccinology systems immunology microbiome innate immunity rabies vaccine antibody T cells metabolism Get full text access Log in, subscribe or purchase for full access. References 2. Hallander, H.O. ∙ Paniagua, M. ∙ Espinoza, F. ... Calibrated serological techniques demonstrate significant different serum response rates to an oral killed cholera vaccine between Swedish and Nicaraguan children Vaccine. 2002; 21:138-145 3. Dbaibo, G. ∙ Amanullah, A. ∙ Claeys, C. ...
Disease-specific B cell clones are shared between patients with Crohn’s disease - Nature Communications
Abstract B cells have important functions in gut homeostasis, and dysregulated B cell populations are frequently observed in patients with inflammatory bowel diseases, including both ulcerative colitis (UC) and Crohn’s disease (CD). How these B cell perturbations contribute to disease remains largely unknown. Here, we perform deep sequencing of the B cell receptor (BCR) repertoire in four cohorts of patients with CD, together with healthy controls and patients with UC.
Scott Boyd: High-density developments near Main Street threaten Bozeman's very soul
Bozeman is a city at a turning point. It has long held a reputation as one of the most livable cities in the West. But its defining character — its historic neighborhoods, architectural legacy, and cohesive sense of place — is now under pressure from the very growth that has made it so attractive. Since 1991, Bozeman has protected its heritage through a bold and forward-thinking tool: the Neighborhood Conservation Overlay District (NCOD).
Scott Boyd: One weird trick to change Bozeman forever - keep silent!
Keep silent! That’s all it will take for you to allow our commission to irrevocably change Bozeman. Though you may think that’s already happened with all of the changes we see around our downtown, there are more in store. Just for reference, the tallest downtown building, is currently the Armory Hotel, at 110 feet. Not only are they planning to change our skyline and density dramatically, but those changes won’t necessarily benefit the folks needing housing assistance directly or immediately.
Epstein-Barr virus‐associated post‐transplant lymphoproliferative disorders in pediatric transplantation: A prospective multicenter study in the United States - Tajima - 2024 - Pediatric Transplantation - Wiley Online Library
CMV cytomegalovirus CTOTC-06 Clinical Trials in Organ Transplantation in Children 06 D donor EA-D early antigen diffuse component EBNA-1 Epstein–Barr virus nuclear antigen-1 EBV Epstein–Barr virus IQR interquartile range LMP1 latent membrane protein 1 PTLD post-transplant lymphoproliferative disorders R recipient SHR sub-hazard ratio VCA viral capsid antigen WHO World Health Organization 1 INTRODUCTION Post-transplant lymphoproliferative disorders (PTLD) is characterized by abnormal...
Air Force to release tanker recapitalization requirements next month
DAYTON, OH -- The Air Force will release a draft request for information with formal requirements for the KC-135A recapitalization by this September, Scott Boyd, deputy program executive officer for mobility aircraft, said yesterday. Unlike the traditional draft documents or draft requirements, this will be the first time industry will see the formal Air Force requirements and have an opportunity to respond, Boyd said during the Air Force Life Cycle Industry Day.
Space-Based Technocracy: Asgardia Exceeds 1,000,000 Citizens
Posted By: Scott Boyd February 9, 2019 The space cult is run by billionaires at the top level of the United Nations and global elite, and yet they now have over 1 million ‘signups’ who have sword allegiance to the new constitution, which touts Technocracy. No, this isn’t a joke! ⁃ TN Editor A video came out about five months ago that detailed the nation of Asgardia, a newly formed technocracy that is based in space.
Partnership LTC: The Impact and Implications of Exchange Offers
Since 2006, Partnership LTCI has spread across the nation. There have been isolated partnership sales in New York, California, Indiana and Connecticut for over 20 years; however, the Deficit Reduction Act (DRA) passage opened the door for national expansion of the Partnership program. To date, all states with the exception of Alaska, Hawaii, New Mexico and Mississippi have embraced this new DRA Partnership opportunity. What is Partnership LTCI?
LTCI: A Changing Market
Change is difficult to accept, whether you are being forced to take an unfamiliar street due to road construction or forced to alter how you conduct your business. However, it is undeniable that change is going to impact our lives and our business, whether we like it or not. The attitude of “Because that’s the way we’ve always done it here” just can’t rule our business lives. Are you ready to change?
The 3 Levels of "Risk Tolerance" in Long Term Care Planning
Most financial service advisors are accustomed to reviewing a portfolio with an eye for whether an investment recommendation will meet the clients risk tolerance. We contend that long term care planning is no different – both for the consumer and the advisor – and risk tolerance should be able to be used to make the best recommendations in this arena, as well.
Selling Long Term Care Insurance to Affluent Clients: A 3-Step Formula
As a financial planner, it can be difficult to know whether to recommend long term care insurance to your wealthier clients. Many articles have been published suggesting that those with significant assets don’t need long term care insurance in their financial planning because of their ability to self-insure. These articles argue that individuals who are financially capable of self-insuring their long term care risks should do so, rather than purchasing long term care insurance.
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