Keywords Arrhythmia, Anderson-Fabry disease/complications, cardiopulmonary exercise test, echocardiography, electrocardiography, exercise tolerance, heart rate recovery, heart rate response Abstract Patients with Anderson-Fabry disease (AFD) have an elevated incidence of resting arrhythmias and ischemic heart disease, but their exercise arrhythmia burden and ischemic changes are not well understood. In addition, little research has been done on heart rate recovery in these patients.