Shih-Ying Wu
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MyD88-mediated chimaeric antigen receptor macrophages suppress brain metastasis using target-specific phagocytosis - Nature Biomedical Engineering
Abstract Metastatic brain disease occurs in up to 30% of patients with lung, melanoma and breast cancers, and the median survival time remains less than a year. Treating these patients is a challenge because surgical approaches are limited and most chemotherapeutic drugs and immunotherapies are ineffective at crossing the blood–brain barrier (BBB).
Single cell transcriptome profile of mouse skin undergoing antigen driven allergic inflammation recapitulates findings in atopic dermatitis skin lesions
This paper is only available as a PDF. To read, Please Download here. Abstract Background Allergic skin inflammation elicited in mice by epicutaneous (EC) sensitization with antigen shares characteristics with human atopic dermatitis (AD). Objective To characterize gene expression by single cells in mouse skin undergoing antigen-driven allergic inflammation and compare the results with findings in AD skin lesions.
Correction: Loss of XIST in Breast Cancer Activates MSN-c-Met and Reprograms Microglia via Exosomal miRNA to Promote Brain Metastasis
Correction: Loss of XIST in Breast Cancer Activates MSN-c-Met and Reprograms Microglia via Exosomal miRNA to Promote Brain Metastasis Fei Xing, Yin Liu, Shih-Ying Wu, Kerui Wu, Sambad Sharma, Yin-Yuan Mo, Jiamei Feng, Stephanie Sanders, Guangxu Jin, Ravi Singh, Pierre-Alexandre Vidi, Abhishek Tyagi, Michael D. Chan, Jimmy Ruiz, Waldemar Debinski, Boris C. Pasche, Hui-Wen Lo, Linda J. Metheny-Barlow, Ralph B.
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