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Editorial Expression of Concern: CDK4 coexpression with Ras generates malignant human epidermal tumorigenesis
Addendum to: Nature Medicine https://doi.org/10.1038/nm779, published online 23 September 2002. The Editors would like to alert the readers that concerns have been raised about some of the blots presented in this article. Specifically: Fig. 1b, Actin lanes 1, 2 and 4 appear to be similar to Fig. 1d, p14ARF, lanes 1, 2 and 4 and to Fig. 4a, P21CIP1 (IP:p21CIP1), lanes 1,2 and 4; Fig. 1b, Actin and Fig. 4a, P21CIP1 (IP:p21CIP1) appear to be similar; Fig.
DDX50 cooperates with STAU1 to effect stabilization of pro-differentiation RNAs
Keywords RNA helicase DDX50 tissue differentiation glucose STAU1 mRNA stability Research topic(s) CP: Molecular biology Introduction RNA-binding proteins (RBPs) can promote either RNA stability or decay to mediate post-transcriptional control of RNA expression in ways important for cell fate.1,2 The DExD/H-box RNA helicases comprise a family of RBPs that exert diverse impacts on RNA, including on RNA translation, folding, and subcellular localization,3 but their impacts on RNA stability are...
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