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Taekjip Ha on Muck Rack

Taekjip Ha

Boston
As seen in: Nature, Science Magazine, BioRxiv, Cell Press, Cell Reports, Physical Review B, Chemistry World, The Journal of Biological Chemistry
Biophysicist. Howard Hughes Medical Institute. Harvard Medical School. Boston Children’s Hospital. Father of three dragons. Occasional manuscript reviewer.
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Articles

Folding a broken genome: the versatile roles of cohesin in genome maintenance

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By Alberto Marin-Gonzalez, Taekjip Ha
| Nature Verified
Abstract Cohesin is a protein complex that shapes 3D genome organization through two distinct mechanisms. First, cohesin tethers replicated chromatids from DNA replication until mitosis. This process, known as sister chromatid cohesion, ensures accurate chromosome segregation and enables high-fidelity DNA repair through homologous recombination between the sister chromatids.
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Cellular replisomes are powered by flex-fuel motors for unwinding DNA

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By Fahad Rashid, Sushil Pangeni, Chuan Liu, Harish Kumar, Qianyun Yan, Taekjip Ha, James Berger, Gyeongtae Sun Moon
| Nature Verified
Abstract DNA replication relies on hexameric, ring-shaped helicases to unwind parental DNA for supporting fork progression over tens of thousands of base pairs. Oddly, biochemical studies have suggested that, on their own, replicative helicases are rather limited motors that struggle to couple rapid movement to nucleotide turnover (typically believed to be solely ATP). Here, single-molecule studies reveal that when properly loaded, the Escherichia coli (E.
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Bringing the genetically minimal cell to life on a computer in 4D

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By Zane R. Thornburg, Andrew Maytin, Jiwoong Kwon, Troy A. Brier, Benjamin Gilbert, Enguang Fu, Yang-le Gao, Jordan Quenneville, Tianyu Wu, Henry Li, Talia Long, Weria Pezeshkian, Lijie Sun, John I. Glass, Angad P. Mehta, Taekjip Ha, Zaida Luthey-Schulten
| Cell Press Verified
Main text (Cell 189, ▪▪▪–▪▪▪.e1–e21; April 30, 2026) Since the online publication of the article, we, the authors, have become aware of three errors. (1) An additional author was unintentionally omitted in the author list. Following the protocol by co-author Lijie Sun in the STAR Methods, the JCVI staff scientist Daniela Matias de C. Bittencourt made the JCVI-syn3B+FtsZ:mCherry cells that were imaged for the manuscript.
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